Skin science article
Clarins Lip Perfector Versus rhode Peptide Lip Tint
Clarins Lip Perfector Versus rhode Peptide Lip Tint What's inside Key Ingredients Benefits Concerns Ingredients Side-by-side Paraffinum Liquidum Diisostearyl Malate Hydrogenated Styrene/Isoprene Copolymer Paraffin Butyrospermum Parkii Butter Dipentaerythrityl
Clarins Lip Perfector Versus rhode Peptide Lip Tint
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Paraffinum Liquidum
Diisostearyl Malate
Hydrogenated Styrene/Isoprene Copolymer
Paraffin
Butyrospermum Parkii Butter
Dipentaerythrityl Tetrahydroxystearate/Tetraisostearate
Polyethylene
Hydrogenated Polyisobutene
Octyldodecanol
Caprylic/Capric Triglyceride
Synthetic Wax
Nylon-12
Butyrospermum Parkii Butter Unsaponifiables
Irvingia Gabonensis Kernel Butter
Ethylhexyl Palmitate
Parfum
Hydrogenated Coco-Glycerides
Hydrogenated Microcrystalline Wax
Cetyl PEG/PPG-10/1 Dimethicone
Hexyl Laurate
Polyglyceryl-4 Isostearate
Oryzanol
Tribehenin
CI 45380
Ammonium Glycyrrhizate
Tocopheryl Acetate
Sorbitan Isostearate
Triethoxycaprylylsilane
Isopropyl Titanium Triisostearate
Lactic Acid
Palmitoyl Tripeptide-1
BHT
Tocopherol
Mica
Tin Oxide
Silica
Calcium Aluminum Borosilicate
Calcium Sodium Borosilicate
Synthetic Fluorphlogopite
CI 77891
CI 77491
CI 15850
CI 15985
CI 42090
CI 75470
CI 19140
CI 45410
CI 73360
CI 17200
CI 77742
Paraffinum Liquidum, Diisostearyl Malate, Hydrogenated Styrene/Isoprene Copolymer, Paraffin, Butyrospermum Parkii Butter, Dipentaerythrityl Tetrahydroxystearate/Tetraisostearate, Polyethylene, Hydrogenated Polyisobutene, Octyldodecanol, Caprylic/Capric Triglyceride, Synthetic Wax, Nylon-12, Butyrospermum Parkii Butter Unsaponifiables, Irvingia Gabonensis Kernel Butter, Ethylhexyl Palmitate, Parfum, Hydrogenated Coco-Glycerides, Hydrogenated Microcrystalline Wax, Cetyl PEG/PPG-10/1 Dimethicone, Hexyl Laurate, Polyglyceryl-4 Isostearate, Oryzanol, Tribehenin, CI 45380, Ammonium Glycyrrhizate, Tocopheryl Acetate, Sorbitan Isostearate, Triethoxycaprylylsilane, Isopropyl Titanium Triisostearate, Lactic Acid, Palmitoyl Tripeptide-1, BHT, Tocopherol, Mica, Tin Oxide, Silica, Calcium Aluminum Borosilicate, Calcium Sodium Borosilicate, Synthetic Fluorphlogopite, CI 77891, CI 77491, CI 15850, CI 15985, CI 42090, CI 75470, CI 19140, CI 45410, CI 73360, CI 17200, CI 77742
Polybutene
Microcrystalline Wax
Polyglyceryl-2 Triisostearate
Hydrogenated Poly(C6-14 Olefin)
Tetrahexyldecyl Ascorbate
Orbignya Oleifera Seed Oil
Theobroma Grandiflorum Seed Butter
Phytosteryl/Isostearyl/Cetyl/Stearyl/Behenyl Dimer Dilinoleate
Diethylhexyl Syringylidenemalonate
Disteardimonium Hectorite
Hydrogenated Polyisobutene, Diisostearyl Malate, Butyrospermum Parkii Butter, Polybutene, Microcrystalline Wax, Synthetic Wax, Octyldodecanol, Polyglyceryl-2 Triisostearate, Hydrogenated Poly(C6-14 Olefin), Tocopherol, Tocopheryl Acetate, Tetrahexyldecyl Ascorbate, Palmitoyl Tripeptide-1, Orbignya Oleifera Seed Oil, Theobroma Grandiflorum Seed Butter, Lactic Acid, Tribehenin, Caprylic/Capric Triglyceride, Phytosteryl/Isostearyl/Cetyl/Stearyl/Behenyl Dimer Dilinoleate, Ethylhexyl Palmitate, Diethylhexyl Syringylidenemalonate, Sorbitan Isostearate, Disteardimonium Hectorite, CI 77891, CI 15850, CI 19140, CI 42090
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
This ingredient is also known as shea butter. It is a plant-derived extract from the nuts of the Africa shea tree and one of the most well-studied emollients.
Because it has a high concentration of fatty acids (primarily oleic, stearic, and linoleic) it is able to form a protective barrier on the skin's surface. This helps seal in moisture and prevents transepidermal water loss (TEWL).
In vitro research found an increase in skin hydration by 58% and a decrease in TEWL by 37.8% after 24 hours of applying this ingredient (pretty impressive for a single ingredient!).
Besides hydration, shea butter also contains triterpenes that have anti-inflammatory potential. In particule, lupeol cinnamate has shown the highest anti-inflammatory activity in vivo.
Shea butter also contains vitamins A and E which may contribute to antioxidant activity.
While Shea Butter has an SPF rating of about 3-4, it is not a sunscreen replacement.
This ingredient may not be fungal acne safe because its fatty acids fall within the C11-C24 range that the Malassezia yeast can metabolize.
Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.
Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.
In practice, that translates to a long shelf life and a consistently elegant skin feel.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.
Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.
This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.
This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.
Ci 15850 is the pigment color red. It is an azo dye and created synthetically.
Azo dyes need to be thoroughly purified before use. This allows them to be more stable and longer-lasting.
This ingredient is common in foundations, lipsticks, and blushes. This color is described as brown/orangey red.
It has many secondary names such as Red 6 and Red 7. According to a manufacturer, Red 6 usually contains aluminum.
CI 19140 is also known as Tartrazine. Tartrazine is a synthetic dye used in cosmetics, foods, and medicine to add a yellow color.
Tartrazine is created from petroleum and is water-soluble.
Some people may experience allergies from this dye, especially asthmatics and those with an aspirin intolerance.
Ci 42090 is a synthetic dye created from petroleum. It is used to give a bright blue color to cosmetics, medicine, and food.
Ci 77891 is a white pigment from Titanium dioxide. It is naturally found in minerals such as rutile and ilmenite.
It's main function is to add a white color to cosmetics. It can also be mixed with other colors to create different shades.
Ci 77891 is commonly found in sunscreens due to its ability to block UV rays.
Diisostearyl Malate is an emollient and most often used in lip products. It comes from isostearyl alcohol, a fatty acid, and malic acid, an AHA.
As an emollient, Diisostearyl Malate helps create a thin film on your skin to trap moisture in. This helps keep your skin soft and smooth.
Ethylhexyl Palmitate, also known as octyl palmitate, is created from 2-ethylhexyl alcohol and palmitic acid.
In cosmetics, it plays many roles:
One thing worth noting: a controlled study found this ingredient applied under occlusion to acne-prone subjects increased microcomedones. Just keep in mind this was under occlusive conditions and don't reflect how most products are used day-to-day.
For most people, this is a well-tolerated and lightweight ingredient.
This ingredient may not be fungal acne safe because it is an ester of palmitic acid, a C16 fatty acid that falls within the C11-24 range that Malassezia can metabolize.
Hydrogenated Polyisobutene is a synthetic polymer. Polymers are compounds with high molecular weight. Hydrogenated Polyisobutene is an emollient and texture enhancer.
In one study, Hydrogenated Polyisobutene showed better skin hydration levels than Caprylic/Capric Triglyceride. As an emollient, it helps keep your skin soft and hydrated by trapping moisture in.
Hydrogenated Polyisobutene is often used as a mineral oil replacement.
Lactic Acid is another well-loved alpha hydroxy acid (AHA). It is gentler than glycolic acid but still highly effective.
Its main role is to exfoliate the surface of the skin by loosening the “glue” that holds dead skin cells together. Shedding those old cells leads to smoother, softer, and more even-toned skin.
Because lactic acid molecules are larger than glycolic acid, they don’t penetrate as deeply. This means they’re less likely to sting or irritate, making it a great choice for beginners or those with sensitive skin.
Like glycolic acid, it can:
Lactic acid also acts as a humectant (like hyaluronic acid). It can draw water into the skin to improve hydration and also plays a role in the skin's natural moisturizing factor (NMF) in the form of sodium lactate.
Studies show it can boost ceramide production to strengthen the skin barrier and even help balance the skin’s microbiome.
To get results, choose products with a pH between 3-4.
Lower strengths (5-12%) focus on surface exfoliation; higher strengths (12% and up) can reach deeper in the dermis (deeper, supportive layer) to improve skin texture and firmness over time.
Though it was originally derived from milk, most modern lactic acid used in skincare is vegan. It is made through non-dairy fermentation to create a bio-identical and stable form suitable for all formulations.
When lactic acid shows up near the end of an ingredient list, it usually means the brand added just a tiny amount to adjust the product’s pH.
Legend has it that Cleopatra used to bathe in sour milk to help reduce wrinkles.
Lactic acid is truly a gentle multitasker: it exfoliates, hydrates, strengthens, and brightens. It's a great ingredient for giving your skin a smooth, glowing, and healthy look without the harshness of stronger acids.
Read more about some other popular AHA's here:
Octyldodecanol is a fatty alcohol sourced from plant oils like coconut or palm (or made synthetically).
It is:
You'll likely see this in many BHA products because this is the go-to solvent for salicylic acid.
This ingredient is typically used at levels between 2-20%.
Regarding fungal acne: In 2019, this ingredient was tested against multiple Malassezia species (the yeast that causes fungal acne) and showed no growth.
Palmitoyl Tripeptide-1 (aka Pal-GHK) is a synthetic signal peptide made of three amino acids attached to palmitic acid.
That fatty acid attachment is the key: it boosts the peptide's ability to penetrate the skin barrier. This puts it closer to the dermal cells where it can actually make a difference.
Once there, it acts as a matrikine, a signaling peptide that prompts fibroblasts to produce more collagen, fibronectin, and hyaluronic acid.
In vitro studies show it can boost collagen production in skin cells even when UV-damaged skin samples were treated with it at a tiny concentration (it almost fully restored dermal collagen at 5ppm). It achieved this at 100x lower concentration than retinoic acid, which needed 500 ppm to do the same thing.
Human clinical data is promising, but modest:
A study of 23 female volunteers found a small but statistically significant increase (~4%) in skin thickness after treatment at 4 ppm.
A separate small trial of 15 women showed statistically significant reductions in wrinkle length, depth, and skin roughness after applying it twice daily for four weeks.
You'll likely see Pal-GHK paired with Palmitoyl Tetrapeptide-7 as part of the Matrixyl 3000 complex.
Fungal acne note: Usually a palmitic acid component can feed Malassezia in unbound form, but here is is covalently bonded to the peptide. This means it is very difficult for Malassezia to access, and therefore very unlikely to cause fungal acne.
Sorbitan Isostearate is an emulsifer. It is created from isostearic acid and sorbitol.
As an emulsifier, it keeps the water and oil ingredients from separating. This keeps formulas stable and smooth.
In a 24 hour occlusive patch test on 56 subjects, 10% sorbitan isostearate was completely non-irritating. Most formulas use less than 10%.
Because it's a fatty acid ester, it may not be fungal acne safe since the Malassezia yeast can utilize it as a nutrient source.
Synthetic Wax is a manufactured hydrocarbon wax. In formulas, it works as an occlusive emollient that helps reduce water loss and improves the spreadability of products.
Research comparing synthetic wax to traditional mineral-derived products found that formulas containing it perform as well for skin hydration.
It is considered non-comedogenic and vegan-friendly.
This ingredient has a well-established safety record by the CIR Expert Panel for Cosmetic Ingredient Safety.
Synthetic Waxes are straight/branched-chain hydrocarbons with no ester bond or fatty acids. That means there is nothing for the Malassezia yeast to feed on.
Tocopherol is a fat-soluble antioxidant known as Vitamin E.
You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.
Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.
It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.
This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.
Concentrations usually range from 0.1-1% in most leave-on products.
Tocopheryl Acetate is a stable, shelf-friendly form of vitamin E.
Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.
It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.
One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.
Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.
Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.
Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.
The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.
Most leave-on skincare keeps it at the lower end, often between 0.5-1%.
Tribehenin is the triglyceride of glycerin and behenic acid. It is an emollient that helps soften and condition skin.
Safety-wise, this is a well-vetted ingredient. Repeated-insult patch tests of 0.38% tribehenin did not trigger sensitization.
This ingredient may not be fungal acne safe because behenic acid falls into the chain-length range that Malassezia yeasts can feed on.