Skin science article
Clearstem Skincare Bounceback Serum Versus Good Molecules Super Peptide Serum
Clearstem Skincare Bounceback Serum Versus Good Molecules Super Peptide Serum This barrier-repair serum is formulated around Palmitoyl Tripeptide-8 and Copper Tripeptide-1 to strengthen the skin barrier and soften the look of wrinkles. This anti-aging serum is
Clearstem Skincare Bounceback Serum Versus Good Molecules Super Peptide Serum
This barrier-repair serum is formulated around Palmitoyl Tripeptide-8 and Copper Tripeptide-1 to strengthen the skin barrier and soften the look of wrinkles.
This anti-aging serum is formulated around Acetyl Hexapeptide-8 and Acetyl Octapeptide-3 to soften the look of wrinkles and strengthen the skin barrier.
What's inside
Key Ingredients
Benefits
Concerns
No concerns
Ingredients Side-by-side
Water
Glycerin
Propanediol
Maltodextrin
Saccharide Isomerate
Human Bone Marrow Stem Cell Conditioned Media
Camellia Sinensis Leaf Extract
Aloe Barbadensis Leaf Extract
Curcuma Wenyujin/Curcuma Kwangsiensis Rhizome Extract
Angelica Polymorpha Sinensis Root Extract
Palmitoyl Tripeptide-8
Copper Tripeptide-1
Caprooyl Tetrapeptide-3
Argania Spinosa Kernel Oil
Mangifera Indica Fruit Extract
Jasminum Officinale Oil
Swertia Chirata Extract
Physcomitrella Patens Protonema Extract
Isomalt
Caprylyl Glycol
Caprylhydroxamic Acid
Ammonium Polyacryloyldimethyl Taurate
Tetrasodium Glutamate Diacetate
Lactic Acid
Panthenol
Sodium Hyaluronate
Mica
Citric Acid
Sodium Citrate
Dextran
Phospholipids
Butylene Glycol
Polysorbate 20
Water, Glycerin, Propanediol, Maltodextrin, Saccharide Isomerate, Human Bone Marrow Stem Cell Conditioned Media, Camellia Sinensis Leaf Extract, Aloe Barbadensis Leaf Extract, Curcuma Wenyujin/Curcuma Kwangsiensis Rhizome Extract, Angelica Polymorpha Sinensis Root Extract, Palmitoyl Tripeptide-8, Copper Tripeptide-1, Caprooyl Tetrapeptide-3, Argania Spinosa Kernel Oil, Mangifera Indica Fruit Extract, Jasminum Officinale Oil, Swertia Chirata Extract, Physcomitrella Patens Protonema Extract, Isomalt, Caprylyl Glycol, Caprylhydroxamic Acid, Ammonium Polyacryloyldimethyl Taurate, Tetrasodium Glutamate Diacetate, Lactic Acid, Panthenol, Sodium Hyaluronate, Mica, Citric Acid, Sodium Citrate, Dextran, Phospholipids, Butylene Glycol, Polysorbate 20
Ammonium Acryloyldimethyltaurate/Vp Copolymer
1,2-Hexanediol
Diheptyl Succinate
Capryloyl Glycerin/Sebacic Acid Copolymer
Glycine
Xanthan Gum
Ethylhexylglycerin
Acetyl Hexapeptide-8
Acetyl Octapeptide-3
Tocopherol
Water, Propanediol, Glycerin, Ammonium Acryloyldimethyltaurate/Vp Copolymer, 1,2-Hexanediol, Diheptyl Succinate, Capryloyl Glycerin/Sebacic Acid Copolymer, Glycine, Xanthan Gum, Ethylhexylglycerin, Caprylyl Glycol, Acetyl Hexapeptide-8, Acetyl Octapeptide-3, Sodium Hyaluronate, Copper Tripeptide-1, Tocopherol
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Copper Tripeptide-1 (GHK-Cu) is a skin repairing ingredient known for its ability to boost collagen, improve firmness, and support skin regeneration.
It is a complex made up of a naturally occurring peptide (glycine-histidine-lysine) and copper, an essential trace element.
While studying wound healing, researchers noticed GHK-Cu stimulated hair follicle enlargement and growth by keeping hair in its active growth phase longer. This has made it a promising ingredient for hair regrowth treatments.
Some people have reported increased facial hair. While GHK-Cu can make your hair follicles bigger, it usually doesn’t turn soft, barely-visible facial hairs into thick, dark ones.
Anecdotal reports suggest that overusing copper peptides might lead to premature aging due to excess free copper or enzyme imbalances. This claim isn’t backed by large-scale studies.
Unfortunately, there are limited human studies for this ingredient. While early results are promising, many studies are either small, in-vitro, or not rigorously controlled.
For example, there is a 1998 study that explored the effects of copper tripeptide, vitamin C, tretinoin, and melatonin on skin repair and collagen synthesis.
After one month, increased procollagen production was seen in 7 out of 10 participants using copper tripeptide (more than those using vitamin C, melatonin, or tretinoin.
While the study was exploratory, it offers early evidence that copper tripeptide may support collagen production. Larger, well-designed trials are still needed to confirm its potential and understand individual responses.
Read more about other common types of peptides here:
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!