Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Clinique For Men Anti-Age Moisturizer Versus CeraVe Hydrating Hyaluronic Acid Serum

Clinique For Men Anti-Age Moisturizer Versus CeraVe Hydrating Hyaluronic Acid Serum This anti-aging moisturizer is formulated around Squalane and Acetyl Hexapeptide-8 to soften the look of wrinkles and hydrate skin. This hydrating serum is formulated around So

Clinique For Men Anti-Age Moisturizer Versus CeraVe Hydrating Hyaluronic Acid Serum

This anti-aging moisturizer is formulated around Squalane and Acetyl Hexapeptide-8 to soften the look of wrinkles and hydrate skin.

This hydrating serum is formulated around Sodium Hyaluronate and Ceramide NP to hydrate skin and strengthen the skin barrier.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Squalane

Glycerin

Isostearyl Neopentanoate

Butyrospermum Parkii Oil

Butylene Glycol

PEG-100 Stearate

Cetyl Alcohol

Dimethicone

Polyethylene

Glyceryl Stearate

Cucumis Sativus Fruit Extract

Hordeum Vulgare Extract

Sigesbeckia Orientalis Extract

Whey Protein

Caffeine

Acetyl Hexapeptide-8

Sucrose

Petrolatum

Sodium Polyacrylate

Acetyl Glucosamine

Caprylyl Glycol

Propylene Glycol Dicaprate

Helianthus Annuus Seed Extract

Glyceryl Polymethacrylate

Palmitoyl Hexapeptide-12

Tocopheryl Acetate

Sodium Hyaluronate

Dimethicone Crosspolymer-3

Hexylene Glycol

PEG-8

Xanthan Gum

Disodium EDTA

Potassium Sorbate

Phenoxyethanol

Water, Squalane, Glycerin, Isostearyl Neopentanoate, Butyrospermum Parkii Oil, Butylene Glycol, PEG-100 Stearate, Cetyl Alcohol, Dimethicone, Polyethylene, Glyceryl Stearate, Cucumis Sativus Fruit Extract, Hordeum Vulgare Extract, Sigesbeckia Orientalis Extract, Whey Protein, Caffeine, Acetyl Hexapeptide-8, Sucrose, Petrolatum, Sodium Polyacrylate, Acetyl Glucosamine, Caprylyl Glycol, Propylene Glycol Dicaprate, Helianthus Annuus Seed Extract, Glyceryl Polymethacrylate, Palmitoyl Hexapeptide-12, Tocopheryl Acetate, Sodium Hyaluronate, Dimethicone Crosspolymer-3, Hexylene Glycol, PEG-8, Xanthan Gum, Disodium EDTA, Potassium Sorbate, Phenoxyethanol

Cetearyl Ethylhexanoate

Ammonium Polyacryloyldimethyl Taurate

Panthenol

Ceramide NP

Ceramide AP

Ceramide EOP

Carbomer

Cetearyl Alcohol

Behentrimonium Methosulfate

Sodium Hydroxide

Sodium Lauroyl Lactylate

Cholesterol

Isopropyl Myristate

Citric Acid

Phytosphingosine

Ethylhexylglycerin

Water, Glycerin, Cetearyl Ethylhexanoate, Dimethicone, Ammonium Polyacryloyldimethyl Taurate, Sodium Hyaluronate, Panthenol, Ceramide NP, Ceramide AP, Ceramide EOP, Carbomer, Cetearyl Alcohol, Behentrimonium Methosulfate, Sodium Hydroxide, Sodium Lauroyl Lactylate, Cholesterol, Phenoxyethanol, Disodium EDTA, Isopropyl Myristate, Caprylyl Glycol, Citric Acid, Xanthan Gum, Phytosphingosine, Ethylhexylglycerin

Reviews

Be the first to review

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.

What it does:

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 031,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
  4. 04It is a:
  5. 05Humectant, drawing moisture into the skin
  6. 06Emollient, helping to soften skin
  7. 07Solvent, dispersing and stabilizing formulas
  8. 08Preservative booster, enhancing the antimicrobial activity of other preservatives
  9. 09Betaine is a humectant. Like hyaluronic acid, it helps attract and retain moisture in the skin. It’s known for being gentle and for helping the skin maintain balanced hydration.
  10. 10Betaine is mainly used to improve hydration and support calmer skin. It helps skin cells regulate water balance because it functions as an osmolyte.
  11. 11Some studies suggest betaine may support making skin tone more even.
  12. 12Fun fact: Betaine naturally exists in the skin and the body. In cosmetic products, it can be either plant-derived (most commonly from sugar beets) or synthetically produced for consistency and stability.
  13. 13Betaine is also known as trimethylglycine.
  14. 14Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
  15. 15Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
  16. 16Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
  17. 17Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.
  18. 18Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.
  19. 19It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.
  20. 20Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.
Source · skinsort.com
02

Product index

Related product references

Product

Amara Beauty Hyaluronic Acid Serum

Amara Beauty Hyaluronic Acid Serum Amara Beauty Hyaluronic Acid Serum ingredients explained: Deionized Water, Aloe Vera Juice*, Witch Hazel, Cassia Angustifolia Seed Polysaccharide (Botanic…

Source: incidecoder.comView reference →
03

Comparison edit

Read side by side

04

Ask the journal

Related questions

01When and How to Use Hyaluronic Acid in Your Routine

Products with hyaluronic acid can be used in the morning or at night (or both!). Applying the hydrating ingredient at night will restore your skin’s resilience while you sleep, and applying it in the morning will leave your skin feeling plump, hydrated and ready for makeup. Hyaluronic acid is great at providing topical hydration when it’s introduced into a balanced skincare routine. According to Dr. King, it’s important to pair your hyaluronic acid products with an emollient or occlusive moisturizer to lock in hydration.

Source · www.skincare.com
02Is Serum Good for All Skin Types?

Serums are a form of skincare that can be added to any routine no matter what your skin type is. All skin types can benefit from the use of a serum since there are so many different formulations that can target specific skincare concerns. “Serums are used for hydration,to aid [or] maintain the skin barrier, or treat skin issues like acne or rosacea,” says Dr. Lewis. The type of serum that you may use should depend on the skin issue you’re trying to target. Think of serums as a treatment for the skin. “Some serums can reverse damage and help prevent free radicals that cause the signs of aging skin,” adds Dr. Lewis.

Source · www.skincare.com