Skin science article
Clinique Moisture Surge 72-Hour Auto-Replenishing Hydrator Versus CeraVe Hydrating Hyaluronic Acid Serum
Clinique Moisture Surge 72-Hour Auto-Replenishing Hydrator Versus CeraVe Hydrating Hyaluronic Acid Serum This barrier-repair moisturizer is formulated around Sodium Hyaluronate to strengthen the skin barrier and hydrate skin. This hydrating serum is formulated
Clinique Moisture Surge 72-Hour Auto-Replenishing Hydrator Versus CeraVe Hydrating Hyaluronic Acid Serum
This barrier-repair moisturizer is formulated around Sodium Hyaluronate to strengthen the skin barrier and hydrate skin.
This hydrating serum is formulated around Sodium Hyaluronate and Ceramide NP to hydrate skin and strengthen the skin barrier.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Dimethicone
Butylene Glycol
Glycerin
Trisiloxane
Trehalose
Sucrose
Ammonium Acryloyldimethyltaurate/Vp Copolymer
Hydroxyethyl Urea
Camellia Sinensis Leaf Extract
Silybum Marianum Extract
Betula Alba Bark Extract
Saccharomyces Lysate Extract
Aloe Barbadensis Leaf Water
Thermus Thermophillus Ferment
Caffeine
Sorbitol
Palmitoyl Hexapeptide-12
Sodium Hyaluronate
Caprylyl Glycol
Oleth-10
Sodium Polyaspartate
Saccharide Isomerate
Hydrogenated Lecithin
Tocopheryl Acetate
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Glyceryl Polymethacrylate
Tromethamine
PEG-8
Hexylene Glycol
Magnesium Ascorbyl Phosphate
Disodium EDTA
BHT
Phenoxyethanol
CI 14700
CI 19140
Water, Dimethicone, Butylene Glycol, Glycerin, Trisiloxane, Trehalose, Sucrose, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Hydroxyethyl Urea, Camellia Sinensis Leaf Extract, Silybum Marianum Extract, Betula Alba Bark Extract, Saccharomyces Lysate Extract, Aloe Barbadensis Leaf Water, Thermus Thermophillus Ferment, Caffeine, Sorbitol, Palmitoyl Hexapeptide-12, Sodium Hyaluronate, Caprylyl Glycol, Oleth-10, Sodium Polyaspartate, Saccharide Isomerate, Hydrogenated Lecithin, Tocopheryl Acetate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Glyceryl Polymethacrylate, Tromethamine, PEG-8, Hexylene Glycol, Magnesium Ascorbyl Phosphate, Disodium EDTA, BHT, Phenoxyethanol, CI 14700, CI 19140
Cetearyl Ethylhexanoate
Ammonium Polyacryloyldimethyl Taurate
Panthenol
Ceramide NP
Ceramide AP
Ceramide EOP
Carbomer
Cetearyl Alcohol
Behentrimonium Methosulfate
Sodium Hydroxide
Sodium Lauroyl Lactylate
Cholesterol
Isopropyl Myristate
Citric Acid
Xanthan Gum
Phytosphingosine
Ethylhexylglycerin
Water, Glycerin, Cetearyl Ethylhexanoate, Dimethicone, Ammonium Polyacryloyldimethyl Taurate, Sodium Hyaluronate, Panthenol, Ceramide NP, Ceramide AP, Ceramide EOP, Carbomer, Cetearyl Alcohol, Behentrimonium Methosulfate, Sodium Hydroxide, Sodium Lauroyl Lactylate, Cholesterol, Phenoxyethanol, Disodium EDTA, Isopropyl Myristate, Caprylyl Glycol, Citric Acid, Xanthan Gum, Phytosphingosine, Ethylhexylglycerin
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
This ingredient mainly works behind the scenes and helps with:
On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).
Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!