Clinique Moisture Surge™ Hydrating Supercharged Concentrate Versus Neutrogena Hydro Boost Hyaluronic Acid Serum

Clinique Moisture Surge™ Hydrating Supercharged Concentrate Versus Neutrogena Hydro Boost Hyaluronic Acid Serum

This barrier-repair moisturizer is formulated around Acetyl Glucosamine and Sodium Hyaluronate to strengthen the skin barrier and hydrate skin.

This hydrating serum is formulated around Panthenol and Sodium Hyaluronate to hydrate skin and strengthen the skin barrier.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Butylene Glycol

Phenyl Trimethicone

Propanediol

Sucrose

Hydroxyethyl Urea

Alteromonas Ferment Extract

Hydrolyzed Rice Extract

Acetyl Glucosamine

Trehalose

Algae Extract

Caffeine

Cholesterol

Aloe Barbadensis Leaf Water

Sodium Hyaluronate

Pentaerythrityl Tetraethylhexanoate

Dextrin Palmitate

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Sorbitol

Sodium Polyaspartate

Tocopheryl Acetate

Carbomer

Dehydroxanthan Gum

Citric Acid

Tetrahexyldecyl Ascorbate

Benzophenone-4

Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate

Sodium Hydroxide

Sodium Citrate

Disodium EDTA

BHT

Chlorphenesin

Phenoxyethanol

CI 14700

CI 19140

Water, Glycerin, Butylene Glycol, Phenyl Trimethicone, Propanediol, Sucrose, Hydroxyethyl Urea, Alteromonas Ferment Extract, Hydrolyzed Rice Extract, Acetyl Glucosamine, Trehalose, Algae Extract, Caffeine, Cholesterol, Aloe Barbadensis Leaf Water, Sodium Hyaluronate, Pentaerythrityl Tetraethylhexanoate, Dextrin Palmitate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Sorbitol, Sodium Polyaspartate, Tocopheryl Acetate, Carbomer, Dehydroxanthan Gum, Citric Acid, Tetrahexyldecyl Ascorbate, Benzophenone-4, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Sodium Hydroxide, Sodium Citrate, Disodium EDTA, BHT, Chlorphenesin, Phenoxyethanol, CI 14700, CI 19140

Panthenol

Pentylene Glycol

Xylitylglucoside

Anhydroxylitol

Yeast Extract

Xylitol

Hydrolyzed Hyaluronic Acid

Carrageenan

Agar

Potassium Chloride

Xanthan Gum

Ultramarines

Titanium Dioxide

Water, Glycerin, Butylene Glycol, Panthenol, Pentylene Glycol, Phenoxyethanol, Chlorphenesin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Trehalose, Xylitylglucoside, Sodium Hyaluronate, Anhydroxylitol, Disodium EDTA, Sodium Hydroxide, Yeast Extract, Xylitol, Hydrolyzed Hyaluronic Acid, Carrageenan, Agar, Potassium Chloride, Xanthan Gum, Ultramarines, Titanium Dioxide

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products.

As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied.

It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin.

A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Chlorphenesin is a synthetic preservative. It helps protect a product against bacteria in order to extend shelf life. In most cases, Chlorphenesin is paired with other preservatives such as phenoxyethanol and caprylyl glycol.

Chlorphenesin is a biocide. This means it is able to help fight the microorganisms on our skin. It is also able to fight odor-releasing bacteria.

Chlorphenesin is soluble in both water and glycerin.

Studies show Chlorphenesin is easily absorbed by our skin. You should speak with a skincare professional if you have concerns about using Chlorphenesin.

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.

Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.

"Alkaline" refers to a high pH level. A low pH level would be considered acidic.

Trehalose is a disaccharide made of two glucose molecules (glucose is sugar!). Trehalose is used to help moisturize skin. It also has antioxidant properties.

As a humectant, trehalose helps draw moisture from the air to your skin. This helps keep your skin hydrated.

Due to its antioxidant properties, trehalose may help with signs of aging. Antioxidants help fight free-radical molecules, unstable molecules that may damage your skin.

In medicine, trehalose and hyaluronic acid are used to help treat dry eyes.

Some animals, plants, and bacteria create trehalose as a source of energy to survive freeze or lack of water.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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