Clinique Smart Clinical Repair Wrinkle Correcting Serum Versus The INKEY List 1% Retinol Serum

Clinique Smart Clinical Repair Wrinkle Correcting Serum Versus The INKEY List 1% Retinol Serum

This anti-aging serum is formulated around Acetyl Hexapeptide-8 and Palmitoyl Tripeptide-1 to soften the look of wrinkles and refine skin texture.

This anti-aging serum is formulated around Retinol to soften the look of wrinkles and refine skin texture.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Dimethicone

Isododecane

Butylene Glycol

Glycerin

Polysilicone-11

Ascorbyl Glucoside

Sodium Hyaluronate

Tocopheryl Acetate

Squalane

Hypnea Musciformis Extract

Gelidiella Acerosa Extract

Sigesbeckia Orientalis Extract

Helianthus Annuus Seed Extract

Hordeum Vulgare Extract

Triticum Vulgare Germ Extract

Cucumis Sativus Fruit Extract

Caffeine

Acetyl Hexapeptide-8

Palmitoyl Tripeptide-1

Palmitoyl Tetrapeptide-7

Palmitoyl Hexapeptide-12

PEG-10 Dimethicone

Glycyrrhetinic Acid

Whey Protein

Isohexadecane

Propylene Glycol Dicaprate

Caprylyl Glycol

Hydroxypinacolone Retinoate

Acetyl Glucosamine

Cholesterol

PEG-8

Faex Extract

PEG-6

Dimethyl Isosorbide

Glyceryl Polymethacrylate

Polysorbate 20

Sodium Phosphate

Synthetic Fluorphlogopite

Polysorbate 80

Carbomer

Hexylene Glycol

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Acrylamide/Sodium Acryloyldimethyltaurate Copolymer

Potassium Hydroxide

Tin Oxide

Disodium Phosphate

Citric Acid

Disodium EDTA

Sodium Citrate

Phenoxyethanol

Potassium Sorbate

CI 77891

Water, Dimethicone, Isododecane, Butylene Glycol, Glycerin, Polysilicone-11, Ascorbyl Glucoside, Sodium Hyaluronate, Tocopheryl Acetate, Squalane, Hypnea Musciformis Extract, Gelidiella Acerosa Extract, Sigesbeckia Orientalis Extract, Helianthus Annuus Seed Extract, Hordeum Vulgare Extract, Triticum Vulgare Germ Extract, Cucumis Sativus Fruit Extract, Caffeine, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Hexapeptide-12, PEG-10 Dimethicone, Glycyrrhetinic Acid, Whey Protein, Isohexadecane, Propylene Glycol Dicaprate, Caprylyl Glycol, Hydroxypinacolone Retinoate, Acetyl Glucosamine, Cholesterol, PEG-8, Faex Extract, PEG-6, Dimethyl Isosorbide, Glyceryl Polymethacrylate, Polysorbate 20, Sodium Phosphate, Synthetic Fluorphlogopite, Polysorbate 80, Carbomer, Hexylene Glycol, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Potassium Hydroxide, Tin Oxide, Disodium Phosphate, Citric Acid, Disodium EDTA, Sodium Citrate, Phenoxyethanol, Potassium Sorbate, CI 77891

Prunus Armeniaca Kernel Oil

Persea Gratissima Oil

Caprylic/Capric Triglyceride

Cetearyl Alcohol

Glyceryl Stearate Se

Retinol

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Benzyl Alcohol

Phospholipids

Tocopherol

Polyacrylate Crosspolymer-6

Glycine Soja Oil

Ethylhexylglycerin

Glycolipids

Dehydroacetic Acid

Polysorbate 60

Sorbitan Isostearate

Trisodium Ethylenediamine Disuccinate

Glycine Soja Sterols

T-Butyl Alcohol

Water, Glycerin, Prunus Armeniaca Kernel Oil, Persea Gratissima Oil, Caprylic/Capric Triglyceride, Squalane, Cetearyl Alcohol, Glyceryl Stearate Se, Retinol, Phenoxyethanol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Benzyl Alcohol, Phospholipids, Tocopherol, Polyacrylate Crosspolymer-6, Glycine Soja Oil, Ethylhexylglycerin, Glycolipids, Dehydroacetic Acid, Polysorbate 60, Sorbitan Isostearate, Trisodium Ethylenediamine Disuccinate, Glycine Soja Sterols, T-Butyl Alcohol

Reviews

Be the first to review

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Squalane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).

It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.

This is due to how structurally similar it is to what your skin already produces.

Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.

Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.

No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).

Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.

The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.

Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.

A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.

The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons