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Skin science article

Cocokind Ceramide Barrier Serum Versus Paula's Choice Peptide Booster

Cocokind Ceramide Barrier Serum Versus Paula's Choice Peptide Booster This barrier-repair serum is formulated around Aloe Barbadensis Leaf Juice and Beta-Glucan to strengthen the skin barrier and hydrate skin. This anti-aging treatment is formulated around Tri

Cocokind Ceramide Barrier Serum Versus Paula's Choice Peptide Booster

This barrier-repair serum is formulated around Aloe Barbadensis Leaf Juice and Beta-Glucan to strengthen the skin barrier and hydrate skin.

This anti-aging treatment is formulated around Tripeptide-1 and Palmitoyl Tripeptide-1 to soften the look of wrinkles and refine skin texture.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Aloe Barbadensis Leaf Juice

Water

Propanediol

Glycerin

Simmondsia Chinensis Seed Oil

Squalane

Beta-Glucan

Lysolecithin

Sclerotium Gum

Pullulan

Xanthan Gum

Ceramide NP

Ceramide Ns

Ceramide AP

Ceramide Eos

Ceramide EOP

Sodium Levulinate

Sodium Anisate

Tocopherol

Cetyl Alcohol

Caprylyl Glycol

Ceteareth-25

Silica

Caprooyl Phytosphingosine

Caprooyl Sphingosine

Cholesterol

Helianthus Annuus Seed Oil

Glyceryl Caprylate

Phenoxyethanol

Sodium Benzoate

Ethylhexylglycerin

1,2-Hexanediol

Citric Acid

Behenic Acid

Aloe Barbadensis Leaf Juice, Water, Propanediol, Glycerin, Simmondsia Chinensis Seed Oil, Squalane, Beta-Glucan, Lysolecithin, Sclerotium Gum, Pullulan, Xanthan Gum, Ceramide NP, Ceramide Ns, Ceramide AP, Ceramide Eos, Ceramide EOP, Sodium Levulinate, Sodium Anisate, Tocopherol, Cetyl Alcohol, Caprylyl Glycol, Ceteareth-25, Silica, Caprooyl Phytosphingosine, Caprooyl Sphingosine, Cholesterol, Helianthus Annuus Seed Oil, Glyceryl Caprylate, Phenoxyethanol, Sodium Benzoate, Ethylhexylglycerin, 1,2-Hexanediol, Citric Acid, Behenic Acid

PEG-8 Dimethicone

Tripeptide-1

Palmitoyl Tripeptide-1

Palmitoyl Tetrapeptide-7

Palmitoyl Hexapeptide-12

Myristoyl Hexapeptide-16

Myristoyl Pentapeptide-17

Hexanoyl Dipeptide-3 Norleucine Acetate

Azelaoyl Bis-Dipeptide-10

Glycoproteins

Phospholipids

Adenosine

Dipotassium Glycyrrhizate

Arginine

Valine

Glycine

Alanine

Glutamic Acid

Serine

Threonine

Yeast Extract

Isoleucine

Proline

Histidine

Phenylalanine

PCA

Phytic Acid

Panax Ginseng Root Extract

Sodium PCA

Psidium Guajava Fruit Extract

Euterpe Oleracea Fruit Extract

Ahnfeltiopsis Concinna Extract

Dextran

Hydrolyzed Silk

Lecithin

Glyceryl Polymethacrylate

C12-16 Pareth-9

Trideceth-12

Sodium Lactate

Carbomer

Aspartic Acid

Polysorbate 20

Butylene Glycol

PEG-8

C11-15 Pareth-7

Guar Hydroxypropyltrimonium Chloride

Phytosteryl/Octyldodecyl Lauroyl Glutamate

Ectoin

Citrate Buffer

Trimethylsiloxyamodimethicone

Sodium Hydroxide

Water, Glycerin, PEG-8 Dimethicone, Tripeptide-1, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Hexapeptide-12, Myristoyl Hexapeptide-16, Myristoyl Pentapeptide-17, Hexanoyl Dipeptide-3 Norleucine Acetate, Azelaoyl Bis-Dipeptide-10, Glycoproteins, Phospholipids, Adenosine, Dipotassium Glycyrrhizate, Arginine, Valine, Glycine, Alanine, Glutamic Acid, Serine, Threonine, Yeast Extract, Isoleucine, Proline, Histidine, Phenylalanine, PCA, Phytic Acid, Panax Ginseng Root Extract, Sodium PCA, Psidium Guajava Fruit Extract, Euterpe Oleracea Fruit Extract, Ahnfeltiopsis Concinna Extract, Dextran, Hydrolyzed Silk, Lecithin, Glyceryl Polymethacrylate, C12-16 Pareth-9, Trideceth-12, Sodium Lactate, Carbomer, Aspartic Acid, Polysorbate 20, Butylene Glycol, Caprylyl Glycol, PEG-8, C11-15 Pareth-7, Guar Hydroxypropyltrimonium Chloride, Phytosteryl/Octyldodecyl Lauroyl Glutamate, Ectoin, Citrate Buffer, Trimethylsiloxyamodimethicone, Phenoxyethanol, Sodium Hydroxide, Ethylhexylglycerin

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

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Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Alanine is an amino acid and is already found in the human body. Our skin uses alanine to build collagen, elastin, and keratin.
  4. 04Arginine is a semi-essential amino acid. This just means our bodies can product a bit on its own, but sometimes needs a little boost from food sources.
  5. 05It is a part of your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.
  6. 06Here's an interesting thing about Arginine: your skin converts it into urea through the Krebs-Henseleit urea cycle. Urea is one of the most effective humectants your skin naturally produces.
  7. 07A clinical study showed applying 2.5% arginine hydrochloride to atopic dermatitis skin showed significant urea levels in the stratum corneum and improved moisture in just four weeks.
  8. 08Arginine is also a precursor to nitric oxide; nitric oxide improves microcirculation and supports wound healing and collagen synthesis.
  9. 09One study found that an amino acid complex containing Arginine reduced skin irritation, improved hydration, and accelerated skin repair in clinical / in-vivo studies.
  10. 10Arginine itself is an amino acid and not a fatty acid, oil, or ester. On its own, it's not a direct food source for Malassezia, or the yeast that causes fungal acne.
  11. 11Aspartic Acid is an amino acid that our bodies produce naturally. It is an antioxidant.
  12. 12Our body uses Aspartic Acid to help build collagen and elastin. It also plays a role in hydrating skin.
  13. 13Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
  14. 14Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
  15. 15Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
  16. 16Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
  17. 17Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
  18. 18Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
  19. 19Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.
  20. 20Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.
Source · skinsort.com
02

Product index

Related product references

Product

Paula's Choice Peptide Booster

Paula's Choice Peptide Booster Paula's Choice Peptide Booster ingredients explained: Water (Aqua), Glycerin, Peg-8 Dimethicone, Tripeptide-1, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-…

Source: incidecoder.comView reference →
03

Comparison edit

Read side by side