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Cos De BAHA P M.A Peptide Serum Versus Coxir Intensive EGF Peptide Cream

Cos De BAHA P M.A Peptide Serum Versus Coxir Intensive EGF Peptide Cream This anti-aging serum is formulated around Niacinamide and Palmitoyl Tripeptide-1 to soften the look of wrinkles and refine skin texture. This anti-aging moisturizer is formulated around

Cos De BAHA P M.A Peptide Serum Versus Coxir Intensive EGF Peptide Cream

This anti-aging serum is formulated around Niacinamide and Palmitoyl Tripeptide-1 to soften the look of wrinkles and refine skin texture.

This anti-aging moisturizer is formulated around Niacinamide and Sh-Oligopeptide-1 to soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Aloe Barbadensis Leaf Extract

Propanediol

Glycerin

Niacinamide

1,2-Hexanediol

Palmitoyl Tripeptide-1

Palmitoyl Tetrapeptide-7

Acetyl Hexapeptide-8

Panthenol

Sodium Hyaluronate

Beta-Glucan

Adenosine

Allantoin

Butylene Glycol

Carbomer

Polysorbate 20

Caprylyl Glycol

Sodium Lactate

Water

Rosa Damascena Extract

Lavandula Angustifolia Flower Extract

Camellia Sinensis Leaf Extract

Melissa Officinalis Leaf Extract

Artemisia Vulgaris Extract

Aloe Barbadensis Leaf Extract, Propanediol, Glycerin, Niacinamide, 1,2-Hexanediol, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Acetyl Hexapeptide-8, Panthenol, Sodium Hyaluronate, Beta-Glucan, Adenosine, Allantoin, Butylene Glycol, Carbomer, Polysorbate 20, Caprylyl Glycol, Sodium Lactate, Water, Rosa Damascena Extract, Lavandula Angustifolia Flower Extract, Camellia Sinensis Leaf Extract, Melissa Officinalis Leaf Extract, Artemisia Vulgaris Extract

Glyceryl Acrylate/Acrylic Acid Copolymer

Propylene Glycol

Butylene Glycol Dicaprylate/Dicaprate

Dimethicone/Vinyl Dimethicone Crosspolymer

Methyl Gluceth-20

Betaine

Diisostearyl Malate

Cyclomethicone

PEG/PPG-18/4 Copolymer

Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Isohexadecane

Polysorbate 80

Hydrogenated Lecithin

Sh-Oligopeptide-1

Copper Tripeptide-1

Hydrogenated Vegetable Oil

Tri-C14-15 Alkyl Citrate

Myrciaria Dubia Fruit Extract

Malpighia Emarginata Fruit Extract

Tocopheryl Acetate

Arginine

Lonicera Japonica Flower Extract

Solanum Lycopersicum Fruit Extract

Lilium Tigrinum Extract

Nelumbo Nucifera Seed Extract

Chrysanthemum Indicum Flower Extract

Hydrolyzed Collagen

Acanthopanax Senticosus Root Extract

Punica Granatum Fruit Extract

Panax Ginseng Root Extract

Carthamus Tinctorius Flower Extract

Xanthan Gum

Malva Sylvestris Flower Extract

Buddleja Davidii Extract

Thymus Vulgaris Extract

Camellia Sinensis Callus Culture Extract

Phaseolus Radiatus Meristem Cell Culture Extract

Panax Ginseng Callus Culture Extract

Phenoxyethanol

Ethylhexylglycerin

Parfum

Water, Glycerin, Glyceryl Acrylate/Acrylic Acid Copolymer, Propylene Glycol, Butylene Glycol Dicaprylate/Dicaprate, Dimethicone/Vinyl Dimethicone Crosspolymer, Methyl Gluceth-20, Niacinamide, 1,2-Hexanediol, Betaine, Diisostearyl Malate, Cyclomethicone, PEG/PPG-18/4 Copolymer, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Isohexadecane, Polysorbate 80, Adenosine, Butylene Glycol, Hydrogenated Lecithin, Sh-Oligopeptide-1, Copper Tripeptide-1, Hydrogenated Vegetable Oil, Tri-C14-15 Alkyl Citrate, Myrciaria Dubia Fruit Extract, Malpighia Emarginata Fruit Extract, Tocopheryl Acetate, Arginine, Carbomer, Panthenol, Lonicera Japonica Flower Extract, Solanum Lycopersicum Fruit Extract, Lilium Tigrinum Extract, Nelumbo Nucifera Seed Extract, Chrysanthemum Indicum Flower Extract, Hydrolyzed Collagen, Acanthopanax Senticosus Root Extract, Punica Granatum Fruit Extract, Panax Ginseng Root Extract, Carthamus Tinctorius Flower Extract, Xanthan Gum, Malva Sylvestris Flower Extract, Buddleja Davidii Extract, Thymus Vulgaris Extract, Camellia Sinensis Callus Culture Extract, Phaseolus Radiatus Meristem Cell Culture Extract, Panax Ginseng Callus Culture Extract, Phenoxyethanol, Ethylhexylglycerin, Parfum

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.

The way it works is fairly well mapped out:

Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.

The clinical backing is pretty solid too.

A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.

A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.

On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.

This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.

Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.

Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.

It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.

Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.

A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.

There are two forms of panthenol: D and L.

D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.

Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):

Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.

This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.

Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.

This ingredient is also referred to as pro-vitamin B5.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 031,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
  4. 04It is a:
  5. 05Humectant, drawing moisture into the skin
  6. 06Emollient, helping to soften skin
  7. 07Solvent, dispersing and stabilizing formulas
  8. 08Preservative booster, enhancing the antimicrobial activity of other preservatives
  9. 09Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative".
  10. 10It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time.
  11. 11The comparison to Botox does have limits because the molecule is water-loving and relatively large.
  12. 12Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles.
  13. 13So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging.
  14. 14A 12 week human study of a multi-ingredient regimen containing this ingredient saw:
  15. 15While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone).
  16. 16Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations.
  17. 17Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
  18. 18Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
  19. 19Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
  20. 20Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Source · skinsort.com
02

Product index

Related product references

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Cos De BAHA P M.A Peptide Serum

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Source: skinsort.comView reference →

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Neogen Real Peptide Serum

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03

Comparison edit

Read side by side