Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Cosiq CPM 2% Moisturiser With Ceramides + Peptides Versus Dot & Key Skincare Ceramides & Hyaluronic Skin Barrier Repair Face Cream

Cosiq CPM 2% Moisturiser With Ceramides + Peptides Versus Dot & Key Skincare Ceramides & Hyaluronic Skin Barrier Repair Face Cream This anti-aging moisturizer is formulated around Aloe Barbadensis Leaf Extract and Palmitoyl Tetrapeptide-7 to soften the look of

Cosiq CPM 2% Moisturiser With Ceramides + Peptides Versus Dot & Key Skincare Ceramides & Hyaluronic Skin Barrier Repair Face Cream

This anti-aging moisturizer is formulated around Aloe Barbadensis Leaf Extract and Palmitoyl Tetrapeptide-7 to soften the look of wrinkles.

This barrier-repair moisturizer is formulated around Hyaluronic Acid and Ceramide EOP to strengthen the skin barrier and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Aloe Barbadensis Leaf Extract

Glycerin

Propanediol

Palmitoyl Tetrapeptide-7

Palmitoyl Tripeptide-1

Xylitylglucoside

Anhydroxylitol

Xylitol

Benzyl Alcohol

Ethylhexylglycerin

Tocopherol

Cetearyl Alcohol

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Ceramide EOP

Ceramide Ns

Ceramide NP

Ceramide As

Ceramide AP

Cholesterol

Allantoin

Sodium Gluconate

Water, Aloe Barbadensis Leaf Extract, Glycerin, Propanediol, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Xylitylglucoside, Anhydroxylitol, Xylitol, Benzyl Alcohol, Ethylhexylglycerin, Tocopherol, Cetearyl Alcohol, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Ceramide EOP, Ceramide Ns, Ceramide NP, Ceramide As, Ceramide AP, Cholesterol, Allantoin, Sodium Gluconate

Caprylic/Capric Triglyceride

Glyceryl Stearate

PEG-100 Stearate

Cetyl Alcohol

Cetearyl Olivate

Sorbitan Olivate

Dimethicone

Dimethicone Crosspolymer

Cyclopentasiloxane

Hyaluronic Acid

Laminaria Digitata Extract

Cetyl-Pg Hydroxyethyl Palmitamide

Tocopheryl Acetate

Polyglutamic Acid

Lactobacillus

Maltodextrin

Oryza Sativa Bran Water

Cocos Nucifera Oil

Olea Europaea Fruit Oil

Simmondsia Chinensis Seed Oil

Stearic Acid

Sodium Polyacrylate

Dicaprylyl Carbonate

Polyglyceryl-3 Caprate

BHT

Sodium Hydroxide

Xanthan Gum

Disodium EDTA

C14-22 Alcohols

C12-20 Alkyl Glucoside

Water, Caprylic/Capric Triglyceride, Glycerin, Glyceryl Stearate, PEG-100 Stearate, Cetyl Alcohol, Cetearyl Olivate, Sorbitan Olivate, Dimethicone, Dimethicone Crosspolymer, Cyclopentasiloxane, Hyaluronic Acid, Laminaria Digitata Extract, Cetyl-Pg Hydroxyethyl Palmitamide, Ceramide EOP, Ceramide Ns, Ceramide NP, Ceramide As, Ceramide AP, Tocopheryl Acetate, Polyglutamic Acid, Lactobacillus, Maltodextrin, Oryza Sativa Bran Water, Cocos Nucifera Oil, Olea Europaea Fruit Oil, Simmondsia Chinensis Seed Oil, Stearic Acid, Sodium Polyacrylate, Dicaprylyl Carbonate, Polyglyceryl-3 Caprate, Xylitylglucoside, Anhydroxylitol, Xylitol, BHT, Sodium Hydroxide, Xanthan Gum, Disodium EDTA, C14-22 Alcohols, C12-20 Alkyl Glucoside, Benzyl Alcohol, Ethylhexylglycerin, Tocopherol

Reviews

Be the first to review

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

This ingredient is created from dehydrating xylitol in acidic conditions. Xylitol is a famous sugar and humectant.

Much like its predecessor, anhydroxylitol is a humectant. Humectants attract and hold water to moisturize the skin.

This ingredient is most commonly found in a popular trio called Aquaxyl. Aquaxyl is made up of anhydroxylitol (24 - 34%), xylitylglucoside (35 - 50%), and xylitol (5 - 15%).

According to a manufacturer, Aquaxyl is known for a 3-D hydration concept and an anti-dehydration shield to reinforce the outer layer of skin.

This ingredient is often derived from plants such as wood and sugarcane.

Benzyl Alcohol is an aromatic alcohol with several roles: it's a preservative, solvent, and mild fragrance component with a floral scent.

This ingredient has been deemed safe for use in cosmetic formulations at concentrations up to 5%, and up to 10% in hair dyes. You'll typically see 0.5-2% in most rinse-off or leave-on products.

As a preservative, it works by disrupting the membrane of microbial proteins. This helps keep bacteria and fungi from growing in your products.

The sensitization picture is actually quite assuring as well:of nearly 71,000 patients patch tested with benzyl alcohol, only 0.21% showed a positive reaction with most of them being weakly positive.

This led researchers to conclude that benzyl alcohol cannot be regarded as a significant contact allergen.

It is worth noting this ingredient is classified as one of the EU's regulated fragrance allergens and restricted to 1% in finished products.

Labels must also declare it in concentrations above 0.001% in leave-on products and 0.01% in rinse-off products.

At concentrations around 5%, localized redness and itching can appear as a direct irritant response and not as a true allergic reaction.

Ceramide AP is is a skin-identical lipid that mimics what your skin already makes naturally. Ceramides help maintain epidermal integrity and barrier function.

You'll often see this ingredient paired with other ceramides (like ceramide NP), cholesterol, or fatty acids because this combination best mimics the natural lipid mix your skin already has.

The skin's ability to produce ceramides gets disrupted in skin conditions like eczema. This in turn weakens the skin barrier and applying ceramides topically has been shown to replenish what's been lost to restore barrier function.

Most of the studies with Ceramide AP test it as part of a multi-ceramide complex; studies reinforce ceramide AP's role in rebalancing ceramides in skin and improving skin hydration.

Ceramide AS is formally known as Ceramides 4 and 5.

Ceramides are intercellular lipids naturally found in our skin that bonds dead skin cells together to create a barrier. They are known for their ability to hold water and thus are a great ingredient for dry skin.

Ceramide EOP is formally known as Ceramide 1.

It is naturally found in skin and part of the intercellular "mortar" holding everything together in your outermost layer.

EOP stands for a linked Ester fatty acid, a linked Omega hydroxy fatty acid, and the Phytosphingosine base.

What makes Ceramide EOP special is its ultra-long fatty acid chain; this unique structure allows it to bridge the lipid layers in your skin barrier to prevent water loss (something no other ceramide can do).

Low levels of Ceramide EOP have been found in people with eczema and psoriasis.

Using it together with other ceramides, cholesterol, and linoleic acid have been shown to meaningfully improve hydration and reduce water loss.

In one clinical study, a regimen using Ceramide EOP, NP, and AP led to significant symptom improvements in patients with eczema, psoriasis, and dry skin in just 4 weeks.

You'll usually see concentrations between 0.1-0.5% in formulations. Overall, this is a well-tolerated and safe ingredient for cosmetic use.

Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.

Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.

This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.

A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.

Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.

Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.

Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.

Ceramide NS is formally known as Ceramide 2. It is one of the major ceramides in the stratum corneum (outermost layer of skin) plays a role in forming a protective barrier.

Due to its structure, skin lipids can be packed tightly and in turn, this strengthens the barrier and reduces water loss.

Studies show conditions like atopic dermatitis can worsen when ceramide NS levels are low.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Tocopherol is a fat-soluble antioxidant known as Vitamin E.

You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xylitol is a humectant and prebiotic. It can help with dry skin.

In studies, xylitol has been shown to improve dry skin. It decreased transepidermal water loss, or when water passes through the skin and evaporates. Xylitol also showed to help improve the biomechanical properties of the skin barrier.

The prebiotic property of xylitol may also help reinforce our skin's natural microbiome. Having a healthy microbiome prevents infection by bad bacteria and helps with hydration.

As a humectant, Xylitol helps draw moisture from both the air and from deeper skin layers. This helps keep skin hydrated.

Xylitol is a sugar alcohol and commonly used as a sugar substitute. It is naturally occurring in plants such as strawberries and pumpkin.

Xylitylglucoside is created from xylitol and glucose, two humectants.

Not surprisingly, this ingredient is also a humectant. It attracts and holds water in your skin, helping to maintain hydration.

This ingredient is most commonly found in a popular trio called Aquaxyl. Aquaxyl is made up of anhydroxylitol(24 - 34%), xylitylglucoside (35 - 50%), and xylitol (5 - 15%).

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
  4. 04Topically, glycerin does several things at once:
  5. 05Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
  6. 06Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
  7. 07This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
  8. 08Just know very high concentrations (>40%) can feel tacky in low humidity.
  9. 09Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
  10. 10Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
  11. 11So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
  12. 12You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Source · skinsort.com
02

Product index

Related product references

03

Comparison edit

Read side by side