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Skin science article

COSRX Advanced Snail 92 All In One Cream Versus The INKEY List Ceramide Night Treatment

COSRX Advanced Snail 92 All In One Cream Versus The INKEY List Ceramide Night Treatment This barrier-repair moisturizer is formulated around Snail Secretion Filtrate and Allantoin to strengthen the skin barrier and hydrate skin. This barrier-repair night moist

COSRX Advanced Snail 92 All In One Cream Versus The INKEY List Ceramide Night Treatment

This barrier-repair moisturizer is formulated around Snail Secretion Filtrate and Allantoin to strengthen the skin barrier and hydrate skin.

This barrier-repair night moisturizer is formulated around Sodium Hyaluronate and Ceramide NP to strengthen the skin barrier and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Snail Secretion Filtrate

Betaine

Caprylic/Capric Triglyceride

Butylene Glycol

Cetearyl Olivate

Sorbitan Olivate

Cetearyl Alcohol

Carbomer

Ethyl Hexanediol

Phenoxyethanol

Arginine

Dimethicone

Sodium Polyacrylate

Sodium Hyaluronate

Allantoin

Palmitic Acid

Panthenol

Xanthan Gum

Stearic Acid

Adenosine

Water

Myristic Acid

Snail Secretion Filtrate, Betaine, Caprylic/Capric Triglyceride, Butylene Glycol, Cetearyl Olivate, Sorbitan Olivate, Cetearyl Alcohol, Carbomer, Ethyl Hexanediol, Phenoxyethanol, Arginine, Dimethicone, Sodium Polyacrylate, Sodium Hyaluronate, Allantoin, Palmitic Acid, Panthenol, Xanthan Gum, Stearic Acid, Adenosine, Water, Myristic Acid

Glycerin

Simmondsia Chinensis Seed Oil

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Benzyl Alcohol

Squalane

Sodium Lauroyl Lactylate

Sodium PCA

Sodium Hydroxide

Sodium Stearoyl Glutamate

Sodium Lactate

Aspartic Acid

Ethylhexylglycerin

Sodium Gluconate

PCA

Polysorbate 60

Dehydroacetic Acid

Ceramide NP

Glycine

Alanine

Sorbitan Isostearate

Ceramide AP

Phytosphingosine

Serine

Cholesterol

Valine

Isoleucine

Proline

Threonine

Histidine

Phenylalanine

Ceramide EOP

Water, Butylene Glycol, Glycerin, Sodium Hyaluronate, Simmondsia Chinensis Seed Oil, Carbomer, Phenoxyethanol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Benzyl Alcohol, Squalane, Sodium Lauroyl Lactylate, Sodium PCA, Sodium Hydroxide, Sodium Stearoyl Glutamate, Sodium Lactate, Arginine, Aspartic Acid, Ethylhexylglycerin, Sodium Gluconate, PCA, Polysorbate 60, Dehydroacetic Acid, Ceramide NP, Glycine, Alanine, Sorbitan Isostearate, Ceramide AP, Phytosphingosine, Serine, Cholesterol, Valine, Xanthan Gum, Isoleucine, Proline, Threonine, Histidine, Phenylalanine, Ceramide EOP

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Arginine is a semi-essential amino acid. This just means our bodies can product a bit on its own, but sometimes needs a little boost from food sources.

It is a part of your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.

Here's an interesting thing about Arginine: your skin converts it into urea through the Krebs-Henseleit urea cycle. Urea is one of the most effective humectants your skin naturally produces.

A clinical study showed applying 2.5% arginine hydrochloride to atopic dermatitis skin showed significant urea levels in the stratum corneum and improved moisture in just four weeks.

Arginine is also a precursor to nitric oxide; nitric oxide improves microcirculation and supports wound healing and collagen synthesis.

One study found that an amino acid complex containing Arginine reduced skin irritation, improved hydration, and accelerated skin repair in clinical / in-vivo studies.

Arginine itself is an amino acid and not a fatty acid, oil, or ester. On its own, it's not a direct food source for Malassezia, or the yeast that causes fungal acne.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.

Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.

It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.

Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.

A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

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Formula cabinet

Ingredients & structured notes

Ingredient index

The Inkey List 15% Vitamin C And EGF SerumIngredients explained

  1. 01Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product.
  2. 02It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water.
  3. 03Expand to read more
  4. 04Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying.
  5. 05One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time.
  6. 06A form of skincare superstar, vitamin C. If you do not know why vitamin C is such a big deal in skincare, we have a really detailed, geeky description that's good to read. :)
  7. 07So now you know that because pure vitamin C is such a diva (very unstable and hard to formulate) the cosmetic industry is trying to come up with some derivatives that have the badass anti-aging properties of vitamin C (antioxidant protection + colla…
  8. 08First, it's really stable and easy to formulate, so the problems that come with pure vitamin C are solved here.
  9. 09Second, in vitro (meaning made in the lab, not on real humans) studies show that ascorbyl glucoside can penetrate the skin. This is kind of important for an anti-aging ingredient to do the job, so this is good news, though in-vivo (made on real huma…
  10. 10Third, in-vitro studies show that after ascorbyl glucoside is absorbed into the skin it is converted to pure vitamin C (though the rate of conversion is still a question mark). It also shows all the three anti-aging benefits (antioxidant protection …
  11. 11Bottom line: ascorbyl glucoside is one of the best and most promising vitamin C derivatives that shows similar benefits to that of pure vitamin C, but it's less proven (in vivo vs. in vitro studies) and the extent of the benefits are also not the same.
  12. 12The unfancy name for it is lye. It’s a solid white stuff that’s very alkaline and used in small amounts to adjust the pH of the product and make it just right.
  13. 13For example, in case of AHA or BHA exfoliants, the right pH is super-duper important, and pH adjusters like sodium hydroxide are needed.
  14. 14BTW, lye is not something new. It was already used by ancient Egyptians to help oil and fat magically turn into something else. Can you guess what? Yes, it’s soap. It still often shows up in the ingredient list of soaps and other cleansers.
  15. 15Sodium hydroxide in itself is a potent skin irritant, but once it's reacted (as it is usually in skin care products, like exfoliants) it is totally harmless.
  16. 16A mildly viscous, amber-colored liquid with fatty odor, made from Castor Oil and polyethylene glycol (PEG).
  17. 17If it were a person, we’d say, it’s agile, diligent & multifunctional. It’s mostly used as an emulsifier and surfactant but most often it is used to solubilize fragrances into water-based formulas.
  18. 18It’s pretty much the current IT-preservative. It’s safe and gentle, but even more importantly, it’s not a feared-by-everyone-mostly-without-scientific-reason paraben.
  19. 19It’s not something new: it was introduced around 1950 and today it can be used up to 1% worldwide. It can be found in nature - in green tea - but the version used in cosmetics is synthetic.
  20. 20Other than having a good safety profile and being quite gentle to the skin it has some other advantages too. It can be used in many types of formulations as it has great thermal stability (can be heated up to 85°C) and works on a wide range of pH le…
Source · incidecoder.com
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Product index

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Comparison edit

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