Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

COSRX Balancium Comfort Cool Ceramide Soothing Gel Cream Versus First Aid Beauty Ultra Repair Barriair cream

COSRX Balancium Comfort Cool Ceramide Soothing Gel Cream Versus First Aid Beauty Ultra Repair Barriair cream This barrier-repair moisturizer is formulated around Squalane and Ceramide NP to strengthen the skin barrier and calm redness. This barrier-repair mois

COSRX Balancium Comfort Cool Ceramide Soothing Gel Cream Versus First Aid Beauty Ultra Repair Barriair cream

This barrier-repair moisturizer is formulated around Squalane and Ceramide NP to strengthen the skin barrier and calm redness.

This barrier-repair moisturizer is formulated around Ceramide Ng and Linoleic Acid to strengthen the skin barrier and calm redness.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Butylene Glycol

Glycerin

Helianthus Annuus Seed Oil

Squalane

PCA Dimethicone

Phenyl Trimethicone

Polyglyceryl-3 Methylglucose Distearate

Polyglycerin-3

Dipropylene Glycol

Ceramide NP

Betaine

Hydrogenated Lecithin

Hydroxyacetophenone

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Sodium Polyacrylate

Xylitol

Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Caprylyl Glycol

Glyceryl Stearate

Polyisobutene

Polyquaternium-51

Ethylhexylglycerin

Caprylic/Capric Triglyceride

Disodium EDTA

1,2-Hexanediol

Caprylyl/Capryl Glucoside

Sorbitan Oleate

Mentha Piperita Leaf Extract

Zingiber Officinale Root Extract

Menthyl Lactate

Ethyl Menthane Carboxamide

Methyl Diisopropyl Propionamide

Leuconostoc/Radish Root Ferment Filtrate

Centella Asiatica Leaf Extract

Anthemis Nobilis Flower Water

Glycyrrhiza Glabra Root Extract

Aloe Barbadensis Leaf Juice

Chamaecyparis Obtusa Water

Citrus Aurantium Bergamia Fruit Oil

Dipotassium Glycyrrhizate

Melaleuca Alternifolia Leaf Oil

Aniba Rosaeodora Wood Oil

Tocopherol

Cetearyl Alcohol

Stearic Acid

Sodium Hyaluronate

Hydrolyzed Hyaluronic Acid

Allantoin

Panthenol

Palmitoyl Pentapeptide-4

Phytosphingosine

Cholesterol

Ceramide Ng

Ceramide Ns

Ceramide AP

Ceramide As

Ceramide EOP

Water, Butylene Glycol, Glycerin, Helianthus Annuus Seed Oil, Squalane, PCA Dimethicone, Phenyl Trimethicone, Polyglyceryl-3 Methylglucose Distearate, Polyglycerin-3, Dipropylene Glycol, Ceramide NP, Betaine, Hydrogenated Lecithin, Hydroxyacetophenone, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Sodium Polyacrylate, Xylitol, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Caprylyl Glycol, Glyceryl Stearate, Polyisobutene, Polyquaternium-51, Ethylhexylglycerin, Caprylic/Capric Triglyceride, Disodium EDTA, 1,2-Hexanediol, Caprylyl/Capryl Glucoside, Sorbitan Oleate, Mentha Piperita Leaf Extract, Zingiber Officinale Root Extract, Menthyl Lactate, Ethyl Menthane Carboxamide, Methyl Diisopropyl Propionamide, Leuconostoc/Radish Root Ferment Filtrate, Centella Asiatica Leaf Extract, Anthemis Nobilis Flower Water, Glycyrrhiza Glabra Root Extract, Aloe Barbadensis Leaf Juice, Chamaecyparis Obtusa Water, Citrus Aurantium Bergamia Fruit Oil, Dipotassium Glycyrrhizate, Melaleuca Alternifolia Leaf Oil, Aniba Rosaeodora Wood Oil, Tocopherol, Cetearyl Alcohol, Stearic Acid, Sodium Hyaluronate, Hydrolyzed Hyaluronic Acid, Allantoin, Panthenol, Palmitoyl Pentapeptide-4, Phytosphingosine, Cholesterol, Ceramide Ng, Ceramide Ns, Ceramide AP, Ceramide As, Ceramide EOP

Propanediol

Cetyl Ethylhexanoate

Polymethyl Methacrylate

Oxygen

Linoleic Acid

Linolenic Acid

Chrysanthemum Parthenium Extract

Camellia Sinensis Leaf Extract

Colloidal Oatmeal

Hydrolyzed Yeast Extract

Cetyl Hydroxyethylcellulose

Polyglucuronic Acid

Cetyl Alcohol

Sodium Polyacrylate Starch

Polypropylene

Polysorbate 80

Steareth-30

Lecithin

Phenoxyethanol

Perfluorohexane

Chlorphenesin

Perfluoromethylcyclopentane

Sodium Benzoate

Potassium Sorbate

Water, Glycerin, Propanediol, Cetyl Ethylhexanoate, Caprylic/Capric Triglyceride, Polymethyl Methacrylate, Oxygen, Ceramide Ng, Linoleic Acid, Linolenic Acid, Glycyrrhiza Glabra Root Extract, Chrysanthemum Parthenium Extract, Camellia Sinensis Leaf Extract, Sodium Hyaluronate, Tocopherol, Colloidal Oatmeal, Caprylyl Glycol, Hydrolyzed Yeast Extract, Cetyl Hydroxyethylcellulose, Cholesterol, Polyglucuronic Acid, Cetyl Alcohol, Sodium Polyacrylate Starch, Stearic Acid, Dipropylene Glycol, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Glyceryl Stearate, Sodium Polyacrylate, Polypropylene, Polysorbate 80, Steareth-30, Lecithin, Ethylhexylglycerin, Leuconostoc/Radish Root Ferment Filtrate, Phenoxyethanol, Perfluorohexane, Chlorphenesin, Perfluoromethylcyclopentane, Sodium Benzoate, Potassium Sorbate

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.

Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.

In practice, that translates to a long shelf life and a consistently elegant skin feel.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.

Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.

This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.

This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Ceramide NG is a type of Ceramide. The NG stands for a sphinganine base.

Ceramides are intercellular lipids naturally found in our skin that bonds dead skin cells together to create a barrier. They are known for their ability to hold water and thus are a great ingredient for dry skin.

Ceramides are an important building block for our skin barrier. A stronger barrier helps the skin look more firm and hydrated. By bolstering the skin ceramides act as a barrier against irritating ingredients. This can help with inflammation as well.

If you would like to eat ceramides, sweet potatoes contain a small amount.

Read more about other common types of ceramides here: Ceramide AP Ceramide EOP Ceramide NP

Cholesterol is a lipid that is naturally found in human skin and is one of the three key components of your skin barrier. In skincare, it is an emollient and barrier-repairing ingredient.

It works by fitting directly into the lipid layers of skin to help restore structure and reduce transepidermal water loss (TEWL).

This is a great ingredient for dry, compromised, or aging skin; our skin starts to produce less cholesterol with age.

Research shows cholesterol works best in combination with ceramides and fatty acids, the other two major components in your skin barrier.

Cholesterol is also a well-establish penetration enhancer and can help other actives absorb more effectively.

Cosmetic-grade cholesterol is usually derived from lanolin but plant and synthetic options also exist. We recommend reaching out to the brand if you have questions about their source of cholesterol.

Dipropylene Glycol is a synthetically created humectant, stabilizer, and solvent.

This ingredient helps:

Dipropylene glycol is technically an alcohol, but it belongs to the glycol family (often considered part of the ‘good’ alcohols). This means it is hydrating and gentle on skin unlike drying solvent alcohols like denatured alcohol.

As a masking agent, Dipropylene Glycol can be used to cover the smell of other ingredients. However, it does not have a scent.

Studies show Dipropylene Glycol is considered safe to use in skincare.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Glyceryl Stearate is made by reacting glycerin with stearic acid (typically sourced from plant oils like palm or coconut). It's an emulsifier, emollient, and mild occlusive.

Emulsifiers help ingredients like oil and water stay mixed so your formula stays nicely blended and uniform in texture.

This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototoxic, and non-photoallergenic.

A close cousin of this ingredient is Glyceryl Stearate SE ("self-emulsifying"). This just has a small amount of sodium or potassium stearate added so it can emulsify without a co-emulsifier.

Since this ingredient is an ester of a C18 fatty acid, it may not be fungal acne safe. The Malassezia yeast can potentially metabolize within the C11-C24 range.

Fun fact: The human body also creates Glyceryl Stearate naturally.

Glycyrrhiza Glabra Root Extract is an extract of the roots of Licorice. It has been found to have several benefits such as skin hydrating, conditioning, and soothing.

One component, glabridin, has extra potent antioxidant and soothing properties. It has also been found to block pigmentation from UVB rays in guinea pigs.

Licorice Root also contains a flavonoid. Flavonoids are a natural substance from in plants. Flavonoids also have antioxidant properties.

Another component, glycyrrhizin, has been found to have anti-inflammatory and antimicrobial benefits. This may make licorice root extract effective at treating acne. However, more research is needed to support this.

Liquiritin is one of the flavone compounds found in licorice. It has been found to help lighten skin by preventing tyrosinase from reacting with tyrosine. When the two react, protein is converted to melanin. Melanin is the substance in your body that gives your features pigmentation.

Leuconostoc/Radish Root Ferment Filtrate is a natural preservative. It comes from fermenting radish roots with a bacteria called leuconostoc. The trade name for this ingredient is Leucidal.

Leuconostoc comes from lactic acid.

This ingredient has antimicrobial properties and helps prevent the growth of bacteria in a product.

Leuconostoc is used to make the traditional Korean side-dish, kimchi. It is also used to make sourdough bread (both incredibly yummy foods).

This long ingredient is a copolymer of sodium acrylate and sodium acryloyldimethyl taurate monomers.

It is used to help stabilize other ingredients and create a thicker gel-like texture.

Emulsifiers prevent oils and waters from separating.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Sodium Polyacrylate is the sodium salt of polyacrylic acid. It is used as an absorber, emollient, and stabilizer.

This ingredient is a super-absorbent polymer - meaning it can absorb 100 to 1000 times its mass in water. As an emollient, Sodium Polyacrylate helps soften and soothe skin. Emollients work by creating a barrier to trap moisture in. This helps keep your skin hydrated.

Stearic Acid is a fatty acid that is already found in your skin. It's one of the free fatty acids that works alongside ceramides and cholesterols to maintain your barrier.

In cosmetics, it is a multitasker:

Safety-wise, the CIR Expert Panel has concluded it to be safe in cosmetics when formulated to be non-irritating and non-sensitizing.

Free stearic acid is a C18 fatty acid that the Malassezia yeast can substrate, so this ingredient may not be fungal acne safe.

Tocopherol is a fat-soluble antioxidant known as Vitamin E.

You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.
  4. 04Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.
  5. 05It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.
  6. 06Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.
  7. 07A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.
  8. 08Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
  9. 09Topically, glycerin does several things at once:
  10. 10Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
  11. 11Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
  12. 12This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
  13. 13Just know very high concentrations (>40%) can feel tacky in low humidity.
  14. 14Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
  15. 15Polysorbate 20 is a gentle, water-soluble emulsifier and mild surfactant. It stops oil and water from separating to keep your formulas blended and stable.
  16. 16It also acts as a mild penetration enhancer by helping active ingredients absorb slightly better.
  17. 17The common safety discussion around this ingredient involves a manufacturing byproduct called 1,4-dioxane.
  18. 18Trace amounts can form during production but the EU's Scientific Committee on Consumer Safety has concluded that levels at/below 10 ppm in finished products are safe (commercial products consistently fall within acceptable margins).
  19. 19True allergic reactions are uncommon and the CIR Expert Panel has confirmed this ingredient to be safe as used in cosmetics.
  20. 20Because it is derived from lauric acid, it may not be fungal acne safe.
Source · skinsort.com
02

Product index

Related product references

03

Comparison edit

Read side by side