Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

COSRX The 6 Peptide Skin Booster Serum Versus The Ordinary Matrixyl 10% + HA

COSRX The 6 Peptide Skin Booster Serum Versus The Ordinary Matrixyl 10% + HA This anti-aging serum is formulated around Niacinamide and Acetyl Hexapeptide-8 to soften the look of wrinkles and strengthen the skin barrier. This anti-aging serum is formulated aro

By Peptide Skincare & Beauty Editorial TeamPublished

COSRX The 6 Peptide Skin Booster Serum Versus The Ordinary Matrixyl 10% + HA

This anti-aging serum is formulated around Niacinamide and Acetyl Hexapeptide-8 to soften the look of wrinkles and strengthen the skin barrier.

This anti-aging serum is formulated around Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7 to soften the look of wrinkles and refine skin texture.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Dipropylene Glycol

Glycerin

Pentylene Glycol

1,2-Hexanediol

Niacinamide

Acetyl Hexapeptide-8

Copper Tripeptide-1

Sh-Polypeptide-121

Dipeptide Diaminobutyroyl Benzylamide Diacetate

Oligopeptide-68

Palmitoyl Tripeptide-8

Allantoin

Sodium Hyaluronate

Acetyl Glucosamine

Serine

Alanine

Glycine

Threonine

Arginine

Proline

Betaine

Sodium PCA

Sodium Lactate

PCA

Glutamic Acid

Lysine Hcl

Tocopherol

Dextran

Glycine Soja Oil

Hydrogenated Lecithin

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Polyacrylate Crosspolymer-6

Butylene Glycol

Xanthan Gum

Ethylhexylglycerin

Adenosine

Polyquaternium-51

Disodium EDTA

Citric Acid

Caprylyl Glycol

T-Butyl Alcohol

Potassium Sorbate

Sodium Oleate

Water, Dipropylene Glycol, Glycerin, Pentylene Glycol, 1,2-Hexanediol, Niacinamide, Acetyl Hexapeptide-8, Copper Tripeptide-1, Sh-Polypeptide-121, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Oligopeptide-68, Palmitoyl Tripeptide-8, Allantoin, Sodium Hyaluronate, Acetyl Glucosamine, Serine, Alanine, Glycine, Threonine, Arginine, Proline, Betaine, Sodium PCA, Sodium Lactate, PCA, Glutamic Acid, Lysine Hcl, Tocopherol, Dextran, Glycine Soja Oil, Hydrogenated Lecithin, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Polyacrylate Crosspolymer-6, Butylene Glycol, Xanthan Gum, Ethylhexylglycerin, Adenosine, Polyquaternium-51, Disodium EDTA, Citric Acid, Caprylyl Glycol, T-Butyl Alcohol, Potassium Sorbate, Sodium Oleate

Palmitoyl Tripeptide-1

Palmitoyl Tetrapeptide-7

Palmitoyl Tripeptide-38

Hydroxypropyl Cyclodextrin

PPG-26-Buteth-26

PEG-40 Hydrogenated Castor Oil

Trisodium Ethylenediamine Disuccinate

Carbomer

Polysorbate 20

Ethoxydiglycol

Phenoxyethanol

Chlorphenesin

Water, Glycerin, Butylene Glycol, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-38, Sodium Hyaluronate, Hydroxypropyl Cyclodextrin, PPG-26-Buteth-26, PEG-40 Hydrogenated Castor Oil, Polyacrylate Crosspolymer-6, Trisodium Ethylenediamine Disuccinate, Carbomer, Polysorbate 20, Ethoxydiglycol, Phenoxyethanol, Chlorphenesin

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Polyacrylate Crosspolymer-6 is a texture enhancer and pH adjuster.

It is be used to thicken water-based products and create a gel-texture with a velvet feel.

One manufacturer claims this ingredient to have a pH range of 2-8 and to be biodegradable.

This ingredient is also known as Sepimax Zen.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative".
  4. 04It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time.
  5. 05The comparison to Botox does have limits because the molecule is water-loving and relatively large.
  6. 06Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles.
  7. 07So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging.
  8. 08A 12 week human study of a multi-ingredient regimen containing this ingredient saw:
  9. 09While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone).
  10. 10Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations.
  11. 11Copper Tripeptide-1 (GHK-Cu) is a skin repairing ingredient known for its ability to boost collagen, improve firmness, and support skin regeneration.
  12. 12It is a complex made up of a naturally occurring peptide (glycine-histidine-lysine) and copper, an essential trace element.
  13. 13While studying wound healing, researchers noticed GHK-Cu stimulated hair follicle enlargement and growth by keeping hair in its active growth phase longer. This has made it a promising ingredient for hair regrowth treatments.
  14. 14Some people have reported increased facial hair. While GHK-Cu can make your hair follicles bigger, it usually doesn’t turn soft, barely-visible facial hairs into thick, dark ones.
  15. 15Anecdotal reports suggest that overusing copper peptides might lead to premature aging due to excess free copper or enzyme imbalances. This claim isn’t backed by large-scale studies.
  16. 16Unfortunately, there are limited human studies for this ingredient. While early results are promising, many studies are either small, in-vitro, or not rigorously controlled.
  17. 17For example, there is a 1998 study that explored the effects of copper tripeptide, vitamin C, tretinoin, and melatonin on skin repair and collagen synthesis.
  18. 18After one month, increased procollagen production was seen in 7 out of 10 participants using copper tripeptide (more than those using vitamin C, melatonin, or tretinoin.
  19. 19While the study was exploratory, it offers early evidence that copper tripeptide may support collagen production. Larger, well-designed trials are still needed to confirm its potential and understand individual responses.
  20. 20Read more about other common types of peptides here:
Source · skinsort.com ⟶
02

Product index

Related product references

Product

COSRX The 6 Peptide Skin Booster

COSRX The 6 Peptide Skin Booster COSRX The 6 Peptide Skin Booster ingredients explained: Niacinamide, Ammonium Acryloyldimethyltaurate/VP Copolymer, Polyacrylate Crosspolymer-6, Butylene Gl…

Source: incidecoder.comView reference →
03

Comparison edit

Read side by side

Continue reading

Related articles