Skin science article
COSRX The Hyaluronic Acid 3 Serum Versus Mary & May 6 Peptide Complex Serum
COSRX The Hyaluronic Acid 3 Serum Versus Mary & May 6 Peptide Complex Serum This hydrating serum is formulated around Sodium Hyaluronate to hydrate skin and strengthen the skin barrier. This anti-aging serum is formulated around Copper Tripeptide-1 and Palmito
COSRX The Hyaluronic Acid 3 Serum Versus Mary & May 6 Peptide Complex Serum
This hydrating serum is formulated around Sodium Hyaluronate to hydrate skin and strengthen the skin barrier.
This anti-aging serum is formulated around Copper Tripeptide-1 and Palmitoyl Pentapeptide-4 to soften the look of wrinkles and refine skin texture.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Butylene Glycol
Propanediol
Glycerin
Sodium Hyaluronate 3%
Pentylene Glycol
1,2-Hexanediol
Diethoxyethyl Succinate
Sodium Polyacryloyldimethyl Taurate
Betaine
Xanthan Gum
Dimethicone
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Sodium PCA
Sodium Lactate
PCA
Glyceryl Acrylate/Acrylic Acid Copolymer
Hydrogenated Lecithin
Ethylhexylglycerin
Serine
Alanine
Glycine
Sodium Phytate
Sorbitan Isostearate
Pvm/Ma Copolymer
Glutamic Acid
Citric Acid
Lysine Hcl
Threonine
Arginine
Sodium Methyl Stearoyl Taurate
Proline
Ceramide NP
Cholesterol
Caprylic/Capric Triglyceride
Phytosphingosine
Stearic Acid
Oleic Acid
Alcohol
Tocopherol
Lactic Acid
Caprylyl Glycol
Caprylhydroxamic Acid
Water, Butylene Glycol, Propanediol, Glycerin, Sodium Hyaluronate 3%, Pentylene Glycol, 1,2-Hexanediol, Diethoxyethyl Succinate, Sodium Polyacryloyldimethyl Taurate, Betaine, Xanthan Gum, Dimethicone, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Sodium PCA, Sodium Lactate, PCA, Glyceryl Acrylate/Acrylic Acid Copolymer, Hydrogenated Lecithin, Ethylhexylglycerin, Serine, Alanine, Glycine, Sodium Phytate, Sorbitan Isostearate, Pvm/Ma Copolymer, Glutamic Acid, Citric Acid, Lysine Hcl, Threonine, Arginine, Sodium Methyl Stearoyl Taurate, Proline, Ceramide NP, Cholesterol, Caprylic/Capric Triglyceride, Phytosphingosine, Stearic Acid, Oleic Acid, Alcohol, Tocopherol, Lactic Acid, Caprylyl Glycol, Caprylhydroxamic Acid
Glycereth-26
Carbomer
Polyglyceryl-10 Laurate
Adenosine
Copper Tripeptide-1
Hexapeptide-11
Hexapeptide-9
Palmitoyl Pentapeptide-4
Palmitoyl Tripeptide-1
Tripeptide-1
Water, Glycereth-26, 1,2-Hexanediol, Butylene Glycol, Glycerin, Arginine, Carbomer, Ethylhexylglycerin, Polyglyceryl-10 Laurate, Adenosine, Caprylyl Glycol, Copper Tripeptide-1, Hexapeptide-11, Hexapeptide-9, Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-1, Tripeptide-1
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
Humectant, drawing moisture into the skin
Emollient, helping to soften skin
Solvent, dispersing and stabilizing formulas
Preservative booster, enhancing the antimicrobial activity of other preservatives
Arginine is a semi-essential amino acid. This just means our bodies can product a bit on its own, but sometimes needs a little boost from food sources.
It is a part of your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.
Here's an interesting thing about Arginine: your skin converts it into urea through the Krebs-Henseleit urea cycle. Urea is one of the most effective humectants your skin naturally produces.
A clinical study showed applying 2.5% arginine hydrochloride to atopic dermatitis skin showed significant urea levels in the stratum corneum and improved moisture in just four weeks.
Arginine is also a precursor to nitric oxide; nitric oxide improves microcirculation and supports wound healing and collagen synthesis.
One study found that an amino acid complex containing Arginine reduced skin irritation, improved hydration, and accelerated skin repair in clinical / in-vivo studies.
Arginine itself is an amino acid and not a fatty acid, oil, or ester. On its own, it's not a direct food source for Malassezia, or the yeast that causes fungal acne.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!