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COSRX The Hyaluronic Acid 3 Serum Versus Mary & May 6 Peptide Complex Serum

COSRX The Hyaluronic Acid 3 Serum Versus Mary & May 6 Peptide Complex Serum This hydrating serum is formulated around Sodium Hyaluronate to hydrate skin and strengthen the skin barrier. This anti-aging serum is formulated around Copper Tripeptide-1 and Palmito

COSRX The Hyaluronic Acid 3 Serum Versus Mary & May 6 Peptide Complex Serum

This hydrating serum is formulated around Sodium Hyaluronate to hydrate skin and strengthen the skin barrier.

This anti-aging serum is formulated around Copper Tripeptide-1 and Palmitoyl Pentapeptide-4 to soften the look of wrinkles and refine skin texture.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Butylene Glycol

Propanediol

Glycerin

Sodium Hyaluronate 3%

Pentylene Glycol

1,2-Hexanediol

Diethoxyethyl Succinate

Sodium Polyacryloyldimethyl Taurate

Betaine

Xanthan Gum

Dimethicone

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Sodium PCA

Sodium Lactate

PCA

Glyceryl Acrylate/Acrylic Acid Copolymer

Hydrogenated Lecithin

Ethylhexylglycerin

Serine

Alanine

Glycine

Sodium Phytate

Sorbitan Isostearate

Pvm/Ma Copolymer

Glutamic Acid

Citric Acid

Lysine Hcl

Threonine

Arginine

Sodium Methyl Stearoyl Taurate

Proline

Ceramide NP

Cholesterol

Caprylic/Capric Triglyceride

Phytosphingosine

Stearic Acid

Oleic Acid

Alcohol

Tocopherol

Lactic Acid

Caprylyl Glycol

Caprylhydroxamic Acid

Water, Butylene Glycol, Propanediol, Glycerin, Sodium Hyaluronate 3%, Pentylene Glycol, 1,2-Hexanediol, Diethoxyethyl Succinate, Sodium Polyacryloyldimethyl Taurate, Betaine, Xanthan Gum, Dimethicone, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Sodium PCA, Sodium Lactate, PCA, Glyceryl Acrylate/Acrylic Acid Copolymer, Hydrogenated Lecithin, Ethylhexylglycerin, Serine, Alanine, Glycine, Sodium Phytate, Sorbitan Isostearate, Pvm/Ma Copolymer, Glutamic Acid, Citric Acid, Lysine Hcl, Threonine, Arginine, Sodium Methyl Stearoyl Taurate, Proline, Ceramide NP, Cholesterol, Caprylic/Capric Triglyceride, Phytosphingosine, Stearic Acid, Oleic Acid, Alcohol, Tocopherol, Lactic Acid, Caprylyl Glycol, Caprylhydroxamic Acid

Glycereth-26

Carbomer

Polyglyceryl-10 Laurate

Adenosine

Copper Tripeptide-1

Hexapeptide-11

Hexapeptide-9

Palmitoyl Pentapeptide-4

Palmitoyl Tripeptide-1

Tripeptide-1

Water, Glycereth-26, 1,2-Hexanediol, Butylene Glycol, Glycerin, Arginine, Carbomer, Ethylhexylglycerin, Polyglyceryl-10 Laurate, Adenosine, Caprylyl Glycol, Copper Tripeptide-1, Hexapeptide-11, Hexapeptide-9, Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-1, Tripeptide-1

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Arginine is a semi-essential amino acid. This just means our bodies can product a bit on its own, but sometimes needs a little boost from food sources.

It is a part of your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.

Here's an interesting thing about Arginine: your skin converts it into urea through the Krebs-Henseleit urea cycle. Urea is one of the most effective humectants your skin naturally produces.

A clinical study showed applying 2.5% arginine hydrochloride to atopic dermatitis skin showed significant urea levels in the stratum corneum and improved moisture in just four weeks.

Arginine is also a precursor to nitric oxide; nitric oxide improves microcirculation and supports wound healing and collagen synthesis.

One study found that an amino acid complex containing Arginine reduced skin irritation, improved hydration, and accelerated skin repair in clinical / in-vivo studies.

Arginine itself is an amino acid and not a fatty acid, oil, or ester. On its own, it's not a direct food source for Malassezia, or the yeast that causes fungal acne.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 031,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
  4. 04It is a:
  5. 05Humectant, drawing moisture into the skin
  6. 06Emollient, helping to soften skin
  7. 07Solvent, dispersing and stabilizing formulas
  8. 08Preservative booster, enhancing the antimicrobial activity of other preservatives
  9. 09Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.
  10. 10The way it works is fairly well mapped out:
  11. 11Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down o…
  12. 12The clinical backing is pretty solid too.
  13. 13A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at…
  14. 14A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.
  15. 15On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.
  16. 16This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.
  17. 17Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.
  18. 18Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
  19. 19Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
  20. 20Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Source · skinsort.com
02

Product index

Related product references

Product

MARY & MAY 6 Peptide Complex Serum

MARY & MAY 6 Peptide Complex Serum MARY & MAY 6 Peptide Complex Serum ingredients explained: Purified Water, Glycereth-26, 1,2-Hexanediol, Butylene Glycol, Glycerin, Arginine, Carbomer, Eth…

Source: incidecoder.comView reference →

Product

Mary & May 6 Peptide Complex Serum

Mary & May 6 Peptide Complex Serum Ingredients in Mary & May 6 Peptide Complex Serum explained: benefits, concerns, and detailed analysis of 17 ingredients including Water, Glycereth-26, an…

Source: skinsort.comView reference →
03

Comparison edit

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