Cream Co. Hyaluronic Acid & Peptide Serum Versus Cream Co. Cloud Milk Serum

Cream Co. Hyaluronic Acid & Peptide Serum Versus Cream Co. Cloud Milk Serum

This hydrating serum is formulated around Niacinamide and Sodium Hyaluronate to hydrate skin and soften the look of wrinkles.

This hydrating serum is formulated around Beta-Glucan and Ceramide NP to hydrate skin and strengthen the skin barrier.

What's inside

Key Ingredients

Benefits

Concerns

No concerns

Ingredients Side-by-side

Water

Butylene Glycol

Glycerin

Niacinamide

Glyceryl Acrylate/Acrylic Acid Copolymer

Propylene Glycol

Pvm/Ma Copolymer

Propanediol

Hydrolyzed Glycosaminoglycans

Sodium Hyaluronate

Hydrolyzed Hyaluronic Acid

Hyaluronic Acid

Sodium Hyaluronate Crosspolymer

Polysorbate 20

Palmitoyl Tripeptide-1

Palmitoyl Tetrapeptide-7

Phenoxyethanol

Sodium PCA

Carbomer

Sodium Hydroxide

Caffeine

Xanthan Gum

Aloe Barbadensis Leaf Juice

Allantoin

Benzoic Acid

Water, Butylene Glycol, Glycerin, Niacinamide, Glyceryl Acrylate/Acrylic Acid Copolymer, Propylene Glycol, Pvm/Ma Copolymer, Propanediol, Hydrolyzed Glycosaminoglycans, Sodium Hyaluronate, Hydrolyzed Hyaluronic Acid, Hyaluronic Acid, Sodium Hyaluronate Crosspolymer, Polysorbate 20, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Phenoxyethanol, Sodium PCA, Carbomer, Sodium Hydroxide, Caffeine, Xanthan Gum, Aloe Barbadensis Leaf Juice, Allantoin, Benzoic Acid

Caprylic/Capric Triglyceride

Coco-Caprylate/Caprate

Caprylyl Glycol

Pentylene Glycol

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Ethylhexylglycerin

Sodium Lauroyl Lactylate

Terminalia Chebula Fruit Extract

Beta-Glucan

Humulus Lupulus Extract

Sodium Lactate

Arginine

Aspartic Acid

PCA

1,2-Hexanediol

Ceramide NP

Glycine

Ceramide AP

Phytosphingosine

Cholesterol

Alanine

Serine

Valine

Proline

Threonine

Isoleucine

Histidine

Phenylalanine

Glucose

Chondrus Crispus Extract

Ceramide EOP

Hydroxypropyltrimonium Hyaluronate

Sodium Acetylated Hyaluronate

Hydrolyzed Sodium Hyaluronate

Potassium Hyaluronate

Water, Glycerin, Caprylic/Capric Triglyceride, Propanediol, Coco-Caprylate/Caprate, Caprylyl Glycol, Pentylene Glycol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Ethylhexylglycerin, Sodium Lauroyl Lactylate, Terminalia Chebula Fruit Extract, Beta-Glucan, Sodium PCA, Humulus Lupulus Extract, Sodium Lactate, Xanthan Gum, Arginine, Aspartic Acid, PCA, 1,2-Hexanediol, Ceramide NP, Glycine, Ceramide AP, Phytosphingosine, Cholesterol, Alanine, Carbomer, Serine, Valine, Proline, Threonine, Isoleucine, Histidine, Phenylalanine, Butylene Glycol, Glucose, Sodium Hyaluronate, Chondrus Crispus Extract, Ceramide EOP, Sodium Hydroxide, Hydroxypropyltrimonium Hyaluronate, Hydrolyzed Hyaluronic Acid, Sodium Acetylated Hyaluronate, Hyaluronic Acid, Sodium Hyaluronate Crosspolymer, Hydrolyzed Sodium Hyaluronate, Potassium Hyaluronate

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.

Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.

It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.

Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.

A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Hyaluronic acid (HA) is a glycosaminoglycan (basically a long sugar chain) that your skin already makes on its own. In your skin, HA lives in the extracellular matrix and acts as the body's moisture reservoir.

Topically, HA is a humectant that binds water and helps skin look more plump, smooth, and hydrated.

The only catch is that HA isn't a single thing; it actually comes in a wide range of molecular weights (~50 - 2,000+ kDA) and size matters.

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

This is why the best HA serums blend the two sizes together so you get the best of both worlds.

The majority of cosmetic HA is produced by bacterial fermentation, typically using Streptococcus or Bacillus strains. Typical use levels in skincare sit around 0.1-2%.

A clinical study using a 0.2% low-molecular weight HA gel showed improvement in facial seborrheic dermatitis with excellent tolerance.

These are some other common types of Hyaluronic Acid:

Hydrolyzed Hyaluronic Acid is hyaluronic acid (HA) that is broken down into lower molecular weight fragments.

It's a humectant that pulls and holds water in the skin to help with hydration, plumpness, and reduce transepidermal water loss.

Because hydrolyzed hyaluronic acid is smaller in size, it can slip past your outermost layer of skin more easily than full-sized HA.

Most formulations will combine all sizes to get the best of both worlds.

Typical usage levels range from 0.01-1%. Any percentage higher than 2% might become goopy and tacky.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Sodium Hyaluronate Crosspolymer is a crosslinked version of sodium hyaluronate. This just means it's linked into a 3D mesh network that lets it be more stable and sit on skin as a cohesive, gel-like film rather than sinking into skin.

A 2016 human skin study found crosslinked HA increased epidermal water content by 7.6% over the control group and reduced transepidermal water loss by 27.8%.

A follow-up clinical trial found that a topical crosslinked HA serum applied after fillers, microneedling, or chemical peels was well-tolerated and enhanced skin quality at 14 / 28 days.

More recent research suggests that concentrations as low as 0.03% can act as a penetration enhancer for other skincare actives.

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.

Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.

"Alkaline" refers to a high pH level. A low pH level would be considered acidic.

Sodium PCA (the salt of PCA) is one of the most well-established humectants in skincare.

Why is it so special? Your skin already makes it naturally; it's a natural component of your skin's Natural Moisturizing Factor (NMF), or the mix of water-binding compounds inside your skin cells that keeps things soft and hydrated.

As a cosmetic ingredient, it grabs water and holds it in the upper layers of skin to smooth roughness and ease dehydration.

There's some clinical support for the NMF approach with a study showing that a cream built to mimic the skin's NMF significantly boosted hydration.

Safety-wise, this ingredient non-irritating, non-comedogenic, and non-phototoxic in testing, with minimal skin absorption.

It also works really well with other hydrators like glycerin or hyaluronic acid, and typical usage is somewhere between 0.2-4%.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

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