Skin science article
Curology Dark Spot Serum Versus Paula's Choice Discoloration Repair Serum
Curology Dark Spot Serum Versus Paula's Choice Discoloration Repair Serum This brightening serum is formulated around Niacinamide and Glycolic Acid to fade the look of dark spots and refine skin texture. This brightening serum is formulated around Niacinamide
Curology Dark Spot Serum Versus Paula's Choice Discoloration Repair Serum
This brightening serum is formulated around Niacinamide and Glycolic Acid to fade the look of dark spots and refine skin texture.
This brightening serum is formulated around Niacinamide and Tranexamic Acid to fade the look of dark spots and brighten dull-looking skin.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Propanediol
Caprylic/Capric Triglyceride
Isodecyl Neopentanoate
Niacinamide
Glycolic Acid
Diheptyl Succinate
Tranexamic Acid
Glycerin
Capryloyl Glycerin/Sebacic Acid Copolymer
Pentylene Glycol
Magnesium Aluminum Silicate
Kojic Dipalmitate
Sodium Hydroxide
Xanthan Gum
Polyglyceryl-10 Laurate
Tocopheryl Acetate
Tetrasodium Glutamate Diacetate
Hydroxyacetophenone
Sclerotium Gum
Lecithin
Polyglyceryl-10 Myristate
Pullulan
Caprylyl Glycol
Aloe Barbadensis Leaf Juice
Glycyrrhiza Glabra Root Extract
Sodium Acetylated Hyaluronate
Sodium Hyaluronate
Sodium Hyaluronate Crosspolymer
Hydrolyzed Sodium Hyaluronate
Ethylhexylglycerin
Water, Propanediol, Caprylic/Capric Triglyceride, Isodecyl Neopentanoate, Niacinamide, Glycolic Acid, Diheptyl Succinate, Tranexamic Acid, Glycerin, Capryloyl Glycerin/Sebacic Acid Copolymer, Pentylene Glycol, Magnesium Aluminum Silicate, Kojic Dipalmitate, Sodium Hydroxide, Xanthan Gum, Polyglyceryl-10 Laurate, Tocopheryl Acetate, Tetrasodium Glutamate Diacetate, Hydroxyacetophenone, Sclerotium Gum, Lecithin, Polyglyceryl-10 Myristate, Pullulan, Caprylyl Glycol, Aloe Barbadensis Leaf Juice, Glycyrrhiza Glabra Root Extract, Sodium Acetylated Hyaluronate, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Hydrolyzed Sodium Hyaluronate, Ethylhexylglycerin
C13-15 Alkane
Dicaprylyl Carbonate
Ethyl Macadamiate
Behenyl Alcohol
Glyceryl Stearate
Butylene Glycol
Silybum Marianum Seed Oil
Tocopherol
Lactobacillus/Coconut Fruit Juice Ferment Filtrate
Bakuchiol
Hydrogenated Lecithin
Allantoin
Glycine Soja Oil
Hexylene Glycol
Boerhavia Diffusa Root Extract
Glycine Soja Sterols
Citric Acid
Sodium Phytate
Malic Acid
Phenoxyethanol
Water, Niacinamide, Glycerin, Tranexamic Acid, C13-15 Alkane, Caprylic/Capric Triglyceride, Dicaprylyl Carbonate, Ethyl Macadamiate, Behenyl Alcohol, Glyceryl Stearate, Butylene Glycol, Silybum Marianum Seed Oil, Tocopherol, Lactobacillus/Coconut Fruit Juice Ferment Filtrate, Lecithin, Bakuchiol, Xanthan Gum, Caprylyl Glycol, Hydrogenated Lecithin, Allantoin, Glycine Soja Oil, Hexylene Glycol, Boerhavia Diffusa Root Extract, Glycine Soja Sterols, Citric Acid, Sodium Phytate, Malic Acid, Phenoxyethanol, Ethylhexylglycerin
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.
Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.
In practice, that translates to a long shelf life and a consistently elegant skin feel.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.
Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.
This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.
This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of phospholipids.
Thanks to its amphiphilic structure (water-loving head and oil-loving tail), it is a true multitasker:
It plays well with most ingredients and is typically used at 0.1-1%. However, concentrations up to 50% have been reported in moisturizers.
Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Tranexamic Acid (TXA) is a synthetic lysine derivative that is becoming one of the most exciting brightening ingredients in skincare.
Originally used in medicine as an anti-hemorrhagic agent, its skin brightening potential was discovered by accident; patients taking it orally started noticing their melasma was fading.
Unlike most brighteners that target tyrosinase (the enzyme that synthesizes melanin), TXA works further upstream. It basically blocks your cells from receiving the signal to produce pigment.
This makes it one of the rare actives that works on three pathways at once:
This makes it effective for treating melasma, post-inflammatory hyperpigmentation (PIH), and sun-induced dark spots.
The most effective cosmetic concentration sits between 2-5% and going higher doesn't boost results.
Side effects are generally mild; occasional irritation, flaking, or dryness have been reported at the start of use. Overall, this ingredient is pretty well tolerated, even by sensitive skin types.
Another perk of this ingredient is that it does not cause photosensitivity, so it's safe to use in the AM and PM.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.