Skin science article
Dear, Klairs Midnight Blue Calming Cream Versus Niod Copper Amino Isolate Serum 2:1 (CAIS2)
Dear, Klairs Midnight Blue Calming Cream Versus Niod Copper Amino Isolate Serum 2:1 (CAIS2) This calming moisturizer is formulated around Centella Asiatica Extract and Ceramide NP to calm redness and strengthen the skin barrier. This serum is formulated around
Dear, Klairs Midnight Blue Calming Cream Versus Niod Copper Amino Isolate Serum 2:1 (CAIS2)
This calming moisturizer is formulated around Centella Asiatica Extract and Ceramide NP to calm redness and strengthen the skin barrier.
This serum is formulated around Lactococcus Ferment Lysate to support the skin barrier and reduce redness.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Cetyl Ethylhexanoate
Butylene Glycol
Glycerin
Sodium Hyaluronate
Caprylic/Capric Triglyceride
Centella Asiatica Extract
Sorbitan Stearate
Cetyl Alcohol
Butyrospermum Parkii Butter
Argania Spinosa Kernel Oil
Simmondsia Chinensis Seed Oil
Sorbitan Sesquioleate
Glyceryl Stearate
Stearic Acid
Portulaca Oleracea Extract
Anthemis Nobilis Flower Extract
Ceramide NP
Polysorbate 60
Candelilla Cera
Chlorphenesin
Tocopheryl Acetate
Xanthan Gum
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Morus Alba Root Extract
Tromethamine
Brassica Oleracea Italica Extract
Guaiazulene
Acetyl Hexapeptide-8
Lecithin
Acetyl Glutamine
Sh-Oligopeptide-1
Sh-Oligopeptide-2
Sh-Polypeptide-1
Sh-Polypeptide-9
Sh-Polypeptide-11
Bacillus/Folic Acid/Soybean Ferment Extract
Caprylyl Glycol
1,2-Hexanediol
Water, Cetyl Ethylhexanoate, Butylene Glycol, Glycerin, Sodium Hyaluronate, Caprylic/Capric Triglyceride, Centella Asiatica Extract, Sorbitan Stearate, Cetyl Alcohol, Butyrospermum Parkii Butter, Argania Spinosa Kernel Oil, Simmondsia Chinensis Seed Oil, Sorbitan Sesquioleate, Glyceryl Stearate, Stearic Acid, Portulaca Oleracea Extract, Anthemis Nobilis Flower Extract, Ceramide NP, Polysorbate 60, Candelilla Cera, Chlorphenesin, Tocopheryl Acetate, Xanthan Gum, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Morus Alba Root Extract, Tromethamine, Brassica Oleracea Italica Extract, Guaiazulene, Acetyl Hexapeptide-8, Lecithin, Acetyl Glutamine, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-9, Sh-Polypeptide-11, Bacillus/Folic Acid/Soybean Ferment Extract, Caprylyl Glycol, 1,2-Hexanediol
Lactococcus Ferment Lysate
Ethyl Linoleate
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Hexanoyl Dipeptide-3 Norleucine Acetate
Myristoyl Nonapeptide-3
Yeast Extract
Soy Amino Acids
Bisabolol
Pseudoalteromonas Exopolysaccharides
Sorbitan Isostearate
Isohexadecane
Polyacrylate Crosspolymer-6
Trisodium Ethylenediamine Disuccinate
Sodium Salicylate
Citric Acid
Sodium Chloride
Potassium Sorbate
Sodium Benzoate
Pentylene Glycol
Ethoxydiglycol
Phenoxyethanol
Water, Lactococcus Ferment Lysate, Glycerin, Ethyl Linoleate, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Hexanoyl Dipeptide-3 Norleucine Acetate, Myristoyl Nonapeptide-3, Yeast Extract, Soy Amino Acids, Bisabolol, Pseudoalteromonas Exopolysaccharides, Lecithin, Sorbitan Isostearate, Isohexadecane, Polysorbate 60, Polyacrylate Crosspolymer-6, Trisodium Ethylenediamine Disuccinate, Sodium Salicylate, Citric Acid, Sodium Chloride, Potassium Sorbate, Sodium Benzoate, Pentylene Glycol, Ethoxydiglycol, Phenoxyethanol, Chlorphenesin
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Chlorphenesin is a synthetic preservative. It helps protect a product against bacteria in order to extend shelf life. In most cases, Chlorphenesin is paired with other preservatives such as phenoxyethanol and caprylyl glycol.
Chlorphenesin is a biocide. This means it is able to help fight the microorganisms on our skin. It is also able to fight odor-releasing bacteria.
Chlorphenesin is soluble in both water and glycerin.
Studies show Chlorphenesin is easily absorbed by our skin. You should speak with a skincare professional if you have concerns about using Chlorphenesin.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of phospholipids.
Thanks to its amphiphilic structure (water-loving head and oil-loving tail), it is a true multitasker:
It plays well with most ingredients and is typically used at 0.1-1%. However, concentrations up to 50% have been reported in moisturizers.
Polysorbate 60 is used to help stabilize products. It is a surfactant and emulsifier. These properties help keep ingredients together in a product. Surfactants help reduce surface tension between ingredients with different states, such as liquids and solids. Emulsifiers help prevent oils and waters from separating.
Polysorbate 60 is sorbitol-based and created from the ethoxylation of sorbitan. Ethoxylation is a chemical reaction used to add ethylene oxide. Sorbitan is a the dehydrated version of sorbitol, a sugar found in fruits.
In this case, the 60 comes from reacting 60 units of ethylene oxide with sorbitan.
Polysorbates are commonly used in medicine and foods.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!