Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Depology Matrixyl® 3000 Collagen Boosting Serum Versus Paula's Choice Pro-Collagen Multi-Peptide Booster

Depology Matrixyl® 3000 Collagen Boosting Serum Versus Paula's Choice Pro-Collagen Multi-Peptide Booster This anti-aging serum is formulated around Matrixyl 3000 and Aloe Barbadensis Leaf Juice to soften the look of wrinkles and hydrate skin. What's inside Key

By Peptide Skincare & Beauty Editorial TeamPublished

Depology Matrixyl® 3000 Collagen Boosting Serum Versus Paula's Choice Pro-Collagen Multi-Peptide Booster

This anti-aging serum is formulated around Matrixyl 3000 and Aloe Barbadensis Leaf Juice to soften the look of wrinkles and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Butylene Glycol

Matrixyl 3000

Aloe Barbadensis Leaf Juice

Glycerin

Portulaca Oleracea Extract

Hyaluronic Acid

Codium Tomentosum Extract

Citrus Paradisi Seed Extract

Cereus Grandiflorus Extract

Polyglyceryl-6 Caprylate

Trehalose

Hydroxyacetophenone

1,2-Hexanediol

Cocos Nucifera Oil

Rosa Canina Fruit Oil

Helianthus Annuus Seed Oil

Allantoin

Stearic Acid

Xanthan Gum

Water, Butylene Glycol, Matrixyl 3000, Aloe Barbadensis Leaf Juice, Glycerin, Portulaca Oleracea Extract, Hyaluronic Acid, Codium Tomentosum Extract, Citrus Paradisi Seed Extract, Cereus Grandiflorus Extract, Polyglyceryl-6 Caprylate, Trehalose, Hydroxyacetophenone, 1,2-Hexanediol, Cocos Nucifera Oil, Rosa Canina Fruit Oil, Helianthus Annuus Seed Oil, Allantoin, Stearic Acid, Xanthan Gum

Pentylene Glycol

Hydrolyzed Yeast Extract

Pyrus Malus Fruit Extract

Dimethicone

Propanediol

Ceramide AP

Glyceryl Glucoside

Palmitoyl Tetrapeptide-72 Amide

Sh-Polypeptide-121

Tridecapeptide-1

Polyglucuronic Acid

Sodium Hyaluronate

C9-12 Alkane

Ammonium Polyacryloyldimethyl Taurate

Polygonum Bistorta Root Extract

Bacillus Ferment

Lecithin

Sodium Phytate

Coco-Caprylate/Caprate

Hexylene Glycol

Cetyl Hydroxyethylcellulose

Ethylhexylglycerin

Caprylyl Glycol

Magnesium Chloride

Potassium Sorbate

Sodium Benzoate

Water, Glycerin, Pentylene Glycol, Hydrolyzed Yeast Extract, Pyrus Malus Fruit Extract, Dimethicone, Propanediol, Ceramide AP, 1,2-Hexanediol, Glyceryl Glucoside, Palmitoyl Tetrapeptide-72 Amide, Sh-Polypeptide-121, Tridecapeptide-1, Polyglucuronic Acid, Sodium Hyaluronate, C9-12 Alkane, Ammonium Polyacryloyldimethyl Taurate, Polygonum Bistorta Root Extract, Bacillus Ferment, Lecithin, Sodium Phytate, Coco-Caprylate/Caprate, Hexylene Glycol, Cetyl Hydroxyethylcellulose, Xanthan Gum, Ethylhexylglycerin, Caprylyl Glycol, Magnesium Chloride, Potassium Sorbate, Sodium Benzoate

Reviews

Be the first to review

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
  4. 04Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
  5. 05Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
  6. 06This ingredient is also known as shea butter. It is a plant-derived extract from the nuts of the Africa shea tree and one of the most well-studied emollients.
  7. 07Because it has a high concentration of fatty acids (primarily oleic, stearic, and linoleic) it is able to form a protective barrier on the skin's surface. This helps seal in moisture and prevents transepidermal water loss (TEWL).
  8. 08In vitro research found an increase in skin hydration by 58% and a decrease in TEWL by 37.8% after 24 hours of applying this ingredient (pretty impressive for a single ingredient!).
  9. 09Besides hydration, shea butter also contains triterpenes that have anti-inflammatory potential. In particule, lupeol cinnamate has shown the highest anti-inflammatory activity in vivo.
  10. 10Shea butter also contains vitamins A and E which may contribute to antioxidant activity.
  11. 11While Shea Butter has an SPF rating of about 3-4, it is not a sunscreen replacement.
  12. 12This ingredient may not be fungal acne safe because its fatty acids fall within the C11-C24 range that the Malassezia yeast can metabolize.
  13. 13Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.
  14. 14Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.
  15. 15In practice, that translates to a long shelf life and a consistently elegant skin feel.
  16. 16While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.
  17. 17Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.
  18. 18This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.
  19. 19This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures…
  20. 20Cetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier.
Source · skinsort.com ⟶
02

Product index

Related product references

Product

Paula's Choice 1% Retinol Treatment

Paula's Choice 1% Retinol Treatment Paula's Choice 1% Retinol Treatment ingredients explained: Salix Alba Extract, Dipotassium Glycyrrhizate, Arctium Lappa, Phytosterols, Cetyl Esters, Tetr…

Source: incidecoder.comView reference →
03

Comparison edit

Read side by side

Continue reading

Related articles