Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Derma E Hydrating Night Cream Versus Olay Regenerist Retinol 24 + Peptide Night Moisturizer

Derma E Hydrating Night Cream Versus Olay Regenerist Retinol 24 + Peptide Night Moisturizer This barrier-repair night moisturizer is formulated around Aloe Barbadensis Leaf Juice and Sodium Hyaluronate to strengthen the skin barrier and hydrate skin. This anti

Derma E Hydrating Night Cream Versus Olay Regenerist Retinol 24 + Peptide Night Moisturizer

This barrier-repair night moisturizer is formulated around Aloe Barbadensis Leaf Juice and Sodium Hyaluronate to strengthen the skin barrier and hydrate skin.

This anti-aging night moisturizer is formulated around Retinol and Niacinamide to soften the look of wrinkles and refine skin texture.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Aloe Barbadensis Leaf Juice

Glycerin

Caprylic/Capric Triglyceride

Macadamia Ternifolia Seed Oil

Stearyl Alcohol

Cetyl Alcohol

Glyceryl Stearate Citrate

Stearic Acid

Glyceryl Stearate

Camellia Sinensis Leaf

Sodium Hyaluronate

Tocopherol

Allantoin

Panthenol

Dimethicone

Ascorbyl Palmitate

Retinyl Palmitate

Simmondsia Chinensis Seed Oil

Xanthan Gum

Capryloyl Glycerin/Sebacic Acid Copolymer

Diheptyl Succinate

Potassium Sorbate

Phenoxyethanol

Ethylhexylglycerin

Parfum

Water, Aloe Barbadensis Leaf Juice, Glycerin, Caprylic/Capric Triglyceride, Macadamia Ternifolia Seed Oil, Stearyl Alcohol, Cetyl Alcohol, Glyceryl Stearate Citrate, Stearic Acid, Glyceryl Stearate, Camellia Sinensis Leaf, Sodium Hyaluronate, Tocopherol, Allantoin, Panthenol, Dimethicone, Ascorbyl Palmitate, Retinyl Palmitate, Simmondsia Chinensis Seed Oil, Xanthan Gum, Capryloyl Glycerin/Sebacic Acid Copolymer, Diheptyl Succinate, Potassium Sorbate, Phenoxyethanol, Ethylhexylglycerin, Parfum

Tapioca Starch

Dimethicone Crosspolymer

Retinol

Retinyl Propionate

Niacinamide

Palmitoyl Pentapeptide-4

Polyacrylamide

C13-14 Isoparaffin

DMDM Hydantoin

Polysorbate 20

Laureth-4

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Laureth-7

Dimethiconol

Polymethylsilsesquioxane

Aminomethyl Propanol

Titanium Dioxide

Disodium EDTA

Iodopropynyl Butylcarbamate

Water, Dimethicone, Glycerin, Tapioca Starch, Dimethicone Crosspolymer, Retinol, Retinyl Propionate, Niacinamide, Palmitoyl Pentapeptide-4, Polyacrylamide, C13-14 Isoparaffin, DMDM Hydantoin, Polysorbate 20, Laureth-4, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Laureth-7, Dimethiconol, Polymethylsilsesquioxane, Aminomethyl Propanol, Titanium Dioxide, Disodium EDTA, Iodopropynyl Butylcarbamate, Caprylic/Capric Triglyceride

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.

Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.

In practice, that translates to a long shelf life and a consistently elegant skin feel.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.

Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.

This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.

This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.

Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.

What it does:

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Side-by-side

  1. 01Water
  2. 02Caprylic/Capric Triglyceride
  3. 03Propanediol
  4. 04Glycerin
  5. 05Tocopheryl Acetate
  6. 06Cetearyl Alcohol
  7. 07Butyrospermum Parkii Butter
  8. 08Panthenol
  9. 09Trehalose
  10. 10Glycine Soja Oil
  11. 11Ammonium Acryloyldimethyltaurate/Vp Copolymer
  12. 12Dimethicone
  13. 13Glyceryl Polymethacrylate
  14. 14Helianthus Annuus Seed Oil
  15. 15Polyglyceryl-10 Stearate
  16. 16Hydrogenated Lecithin
  17. 17Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
  18. 18Carbomer
  19. 19Tromethamine
  20. 20Glyceryl Stearate
Source · skinsort.com
02

Product index

Related product references

03

Comparison edit

Read side by side