Derma E Skin De-Stress Calming CBD Moisturizer Versus Paula's Choice Skin Recovery Replenishing Moisturizer

Derma E Skin De-Stress Calming CBD Moisturizer Versus Paula's Choice Skin Recovery Replenishing Moisturizer

This calming moisturizer is formulated around Aloe Barbadensis Leaf Juice and Cannabidiol - Synthetically Produced to calm redness and hydrate skin.

This barrier-repair moisturizer is formulated around Oenothera Biennis Oil and Panthenol to strengthen the skin barrier and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Aloe Barbadensis Leaf Juice

Caprylic/Capric Triglyceride

Stearic Acid

Cetyl Alcohol

Glyceryl Stearate Citrate

Glycerin

Cannabidiol - Synthetically Produced

Cannabis Sativa Seed Oil

Cannabis Sativa Flower/Leaf/Stem Extract

Simmondsia Chinensis Seed Oil

Panthenol

Allantoin

Tocopheryl Acetate

Ascorbyl Palmitate

Chamomilla Recutita Flower Extract

Pinus Pinaster Bark Extract

Xanthan Gum

Dimethicone

Glyceryl Stearate

Coco-Caprylate

Cetearyl Glucoside

Sodium Hydroxide

Potassium Sorbate

Phenoxyethanol

Ethylhexylglycerin

Water, Aloe Barbadensis Leaf Juice, Caprylic/Capric Triglyceride, Stearic Acid, Cetyl Alcohol, Glyceryl Stearate Citrate, Glycerin, Cannabidiol - Synthetically Produced, Cannabis Sativa Seed Oil, Cannabis Sativa Flower/Leaf/Stem Extract, Simmondsia Chinensis Seed Oil, Panthenol, Allantoin, Tocopheryl Acetate, Ascorbyl Palmitate, Chamomilla Recutita Flower Extract, Pinus Pinaster Bark Extract, Xanthan Gum, Dimethicone, Glyceryl Stearate, Coco-Caprylate, Cetearyl Glucoside, Sodium Hydroxide, Potassium Sorbate, Phenoxyethanol, Ethylhexylglycerin

Cetearyl Ethylhexanoate

Butylene Glycol

Glycereth-26

Oenothera Biennis Oil

Neopentyl Glycol Diheptanoate

Cyclopentasiloxane

PEG-100 Stearate

Cyclohexasiloxane

Palmitoyl Tripeptide-1

Palmitoyl Tetrapeptide-7

Sodium Hyaluronate

Tocopheryl Linoleate

Tocopherol

Magnesium Ascorbyl Phosphate

Dipotassium Glycyrrhizate

Sodium PCA

Anthemis Nobilis Flower Extract

Sodium Ascorbyl Phosphate

Linoleic Acid

Linolenic Acid

Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate

Saccharide Isomerate

Hydroxypropyl Guar

Rosa Moschata Seed Oil

Polysorbate 20

Cetyl Hydroxyethylcellulose

Carbomer

Sodium Citrate

Trisodium EDTA

Batyl Alcohol

Chlorphenesin

Benzoic Acid

Sorbic Acid

Water, Cetearyl Ethylhexanoate, Butylene Glycol, Glycereth-26, Oenothera Biennis Oil, Cetyl Alcohol, Neopentyl Glycol Diheptanoate, Cyclopentasiloxane, Stearic Acid, Glyceryl Stearate, PEG-100 Stearate, Glycerin, Cyclohexasiloxane, Dimethicone, Panthenol, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Sodium Hyaluronate, Tocopheryl Linoleate, Tocopheryl Acetate, Tocopherol, Magnesium Ascorbyl Phosphate, Ascorbyl Palmitate, Dipotassium Glycyrrhizate, Sodium PCA, Anthemis Nobilis Flower Extract, Aloe Barbadensis Leaf Juice, Sodium Ascorbyl Phosphate, Linoleic Acid, Linolenic Acid, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Saccharide Isomerate, Hydroxypropyl Guar, Allantoin, Rosa Moschata Seed Oil, Polysorbate 20, Cetyl Hydroxyethylcellulose, Carbomer, Sodium Citrate, Trisodium EDTA, Batyl Alcohol, Sodium Hydroxide, Phenoxyethanol, Chlorphenesin, Benzoic Acid, Sorbic Acid

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Allantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.

Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.

Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.

It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.

Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.

This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.

Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.

Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.

Aloe Barbadensis Leaf Juice is the filtered, stabilized liquid pressed from the inner gel of the aloe vera leaf.

In cosmetics, it shows up as either soothing active or a water-replacement base. It is roughly 98-99% water and the last 1-2% is an interesting mix of polysaccharides, amino acids, vitamins, minerals, and enzymes.

The polysaccharides do most of the work: they bind water at the skin surface for a light, non-greasy hydration boost. And one of the polysaccharides, glycomannan, is linked to fibroblast stimulation + collagen synthesis. This is also why aloe has such a long track record in wound and burn healing.

This ingredient is also calming with anti-inflammatory and mild antimicrobial activity, making it a great pick for sensitive, irritated, or post-sun skin.

Realistic expectations matter though; the solid evidence is mostly limited to hydration, soothing, and wound support. Deeper claims about anti-aging or sun protection are not well backed, and science reviews note it does not prevent radiation-induced skin injury.

Because it plays well with almost everything, it's commonly used as a base alongside other actives like niacinamide or vitamin C.

Typical usage concentrations range from 0.5% (where hydration benefits already show up) all the way to 90%+ (where it replaces water as the main base).

The safety for this ingredient is well-establish as well. Overall, this is a great supporting ingredient for those who want a boost in hydration.

Ascorbyl Palmitate is a fat-soluble form of vitamin C (Ascorbic Acid) made by combining it with palmitic acid.

It is able to blend easily into creams and oil-based formulas because it dissolves in oils rather than water.

As you may know, regular vitamin C is notorious for breaking down when exposed to sunlight and air. Ascorbyl Palmitate is more stable and degrades at a slower rate.

Research on whether it converts efficiently into active vitamin C once it's applied on your skin is still limited.

Some in-vitro studies suggest it may support collagen production, but it is not considered one of the stronger vitamin C derivatives, like:

Due to the palmitic acid base, this ingredient may not be fungal acne safe. Comedogenic studies have also shown this ingredient to have a rating of 2.

It's also worth keeping in mind that comedogenic and irritancy ratings are tested on individual ingredients, not finished formulas. The final product's formulation, concentration, and other ingredients all play a role in how something actually behaves on your skin.

Cetyl Alcohol is a fatty alcohol. Fatty Alcohols are most often used as an emollient or to thicken a product.

Its main roles are:

Though it has "alcohol" in the name, it is not related to denatured alcohol or ethyl alcohol.

The FDA allows products labeled "alcohol-free" to have fatty alcohols.

This ingredient may not be fungal acne safe. It is a primary fatty alcohol with a chain length above 12 carbons. A study from 2019 show Malassezia can feed on fatty alcohols in this range, so it may trigger fungal acne in those prone to it.

Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.

What it does:

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Glyceryl Stearate is made by reacting glycerin with stearic acid (typically sourced from plant oils like palm or coconut). It's an emulsifier, emollient, and mild occlusive.

Emulsifiers help ingredients like oil and water stay mixed so your formula stays nicely blended and uniform in texture.

This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototoxic, and non-photoallergenic.

A close cousin of this ingredient is Glyceryl Stearate SE ("self-emulsifying"). This just has a small amount of sodium or potassium stearate added so it can emulsify without a co-emulsifier.

Since this ingredient is an ester of a C18 fatty acid, it may not be fungal acne safe. The Malassezia yeast can potentially metabolize within the C11-C24 range.

Fun fact: The human body also creates Glyceryl Stearate naturally.

Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.

There are two forms of panthenol: D and L.

D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.

Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):

Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.

This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.

Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.

This ingredient is also referred to as pro-vitamin B5.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.

Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.

"Alkaline" refers to a high pH level. A low pH level would be considered acidic.

Stearic Acid is a fatty acid that is already found in your skin. It's one of the free fatty acids that works alongside ceramides and cholesterols to maintain your barrier.

In cosmetics, it is a multitasker:

Safety-wise, the CIR Expert Panel has concluded it to be safe in cosmetics when formulated to be non-irritating and non-sensitizing.

Free stearic acid is a C18 fatty acid that the Malassezia yeast can substrate, so this ingredient may not be fungal acne safe.

Tocopheryl Acetate is a stable, shelf-friendly form of vitamin E.

Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.

It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.

One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.

Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.

Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.

The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.

Most leave-on skincare keeps it at the lower end, often between 0.5-1%.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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