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Differin Adapalene Gel 0.1% Acne Treatment Versus Paula's Choice Resist Intensive Wrinkle-Repair Retinol Serum

Differin Adapalene Gel 0.1% Acne Treatment Versus Paula's Choice Resist Intensive Wrinkle-Repair Retinol Serum This acne treatment is formulated around Adapalene to clear breakouts and refine skin texture. This anti-aging serum is formulated around Retinol and

By Peptide Skincare & Beauty Editorial TeamPublished

Differin Adapalene Gel 0.1% Acne Treatment Versus Paula's Choice Resist Intensive Wrinkle-Repair Retinol Serum

This acne treatment is formulated around Adapalene to clear breakouts and refine skin texture.

This anti-aging serum is formulated around Retinol and Tetrahexyldecyl Ascorbate to soften the look of wrinkles and refine skin texture.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Adapalene 0.1%

Carbomer

Disodium EDTA

Methylparaben

Poloxamer 182

Propylene Glycol

Water

Sodium Hydroxide

Adapalene 0.1%, Carbomer, Disodium EDTA, Methylparaben, Poloxamer 182, Propylene Glycol, Water, Sodium Hydroxide

Cyclopentasiloxane

Dimethiconol

Neopentyl Glycol Diheptanoate

Dicaprylyl Carbonate

Caprylic/Capric Triglyceride

Phenyl Trimethicone

Squalane

Bisabolol

Tetrahexyldecyl Ascorbate

Retinol

Tocotrienols

Tocopherol

Lecithin

Laminaria Ochroleuca Extract

Avena Sativa Kernel Extract

Elaeis Guineensis Oil

Stearyl Glycyrrhetinate

Hexylene Glycol

Caprylyl Glycol

Ethylhexylglycerin

Phenoxyethanol

Cyclopentasiloxane, Dimethiconol, Neopentyl Glycol Diheptanoate, Dicaprylyl Carbonate, Caprylic/Capric Triglyceride, Phenyl Trimethicone, Squalane, Bisabolol, Tetrahexyldecyl Ascorbate, Retinol, Tocotrienols, Tocopherol, Lecithin, Laminaria Ochroleuca Extract, Avena Sativa Kernel Extract, Elaeis Guineensis Oil, Stearyl Glycyrrhetinate, Hexylene Glycol, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol

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The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

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Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.
  4. 04Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.
  5. 05This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.
  6. 06A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.
  7. 07Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.
  8. 08Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.
  9. 09Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.
  10. 10Cholesterol is a lipid that is naturally found in human skin and is one of the three key components of your skin barrier. In skincare, it is an emollient and barrier-repairing ingredient.
  11. 11It works by fitting directly into the lipid layers of skin to help restore structure and reduce transepidermal water loss (TEWL).
  12. 12This is a great ingredient for dry, compromised, or aging skin; our skin starts to produce less cholesterol with age.
  13. 13Research shows cholesterol works best in combination with ceramides and fatty acids, the other two major components in your skin barrier.
  14. 14Cholesterol is also a well-establish penetration enhancer and can help other actives absorb more effectively.
  15. 15Cosmetic-grade cholesterol is usually derived from lanolin but plant and synthetic options also exist. We recommend reaching out to the brand if you have questions about their source of cholesterol.
  16. 16Ethylhexyl Stearate mainly acts as an emollient that helps hydate skin. It can also be used to reduce the greasiness of oils in a formula.
  17. 17Because this ingredient contains a C18 fatty acid chain, it may not be Malassezia/fungal acne safe. This is because the Malassezia yeast potentially feeds on C11-C24 fatty acids.
  18. 18This ingredient is an ester of 2-ethylhexyl alcohol and stearic acid.
  19. 19Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
  20. 20Topically, glycerin does several things at once:
Source · skinsort.com ⟶
02

Product index

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03

Comparison edit

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