Skin science article
Dr. Althea 345 Relief Cream Versus First Aid Beauty Ultra Repair Oil-Control Moisturizer
Dr. Althea 345 Relief Cream Versus First Aid Beauty Ultra Repair Oil-Control Moisturizer This calming moisturizer is formulated around Melaleuca Alternifolia Leaf Water and Niacinamide to calm redness and strengthen the skin barrier. This oil-control moisturiz
Dr. Althea 345 Relief Cream Versus First Aid Beauty Ultra Repair Oil-Control Moisturizer
This calming moisturizer is formulated around Melaleuca Alternifolia Leaf Water and Niacinamide to calm redness and strengthen the skin barrier.
This oil-control moisturizer is formulated around Niacinamide and Avena Sativa Kernel Extract to balance excess oil and strengthen the skin barrier.
What's inside
Key Ingredients
Benefits
Concerns
No concerns
Ingredients Side-by-side
Water
Melaleuca Alternifolia Leaf Water
Propanediol
Glycerin
1,2-Hexanediol
Hydrogenated Polydecene
Vinyldimethicone
C14-22 Alcohols
Niacinamide
Caprylic/Capric Triglyceride
Panthenol
Dicaprylyl Carbonate
Butylene Glycol
Ammonium Acryloyldimethyltaurate/Vp Copolymer
Caprylyl Methicone
Polymethylsilsesquioxane
C12-20 Alkyl Glucoside
Hydroxyacetophenone
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Polyquaternium-51
Ethylhexylglycerin
Tromethamine
Sodium Hyaluronate
Sodium Stearoyl Glutamate
Coptis Japonica Root Extract
Centella Asiatica Leaf Water
Beta-Glucan
Resveratrol
Hydrolyzed Hyaluronic Acid
Camellia Sinensis Leaf Water
Tocopherol
Madecassoside
Sodium DNA
Centella Asiatica Extract
Ceramide NP
Tannic Acid
Disodium EDTA
Sodium Phytate
Water, Melaleuca Alternifolia Leaf Water, Propanediol, Glycerin, 1,2-Hexanediol, Hydrogenated Polydecene, Vinyldimethicone, C14-22 Alcohols, Niacinamide, Caprylic/Capric Triglyceride, Panthenol, Dicaprylyl Carbonate, Butylene Glycol, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Caprylyl Methicone, Polymethylsilsesquioxane, C12-20 Alkyl Glucoside, Hydroxyacetophenone, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Polyquaternium-51, Ethylhexylglycerin, Tromethamine, Sodium Hyaluronate, Sodium Stearoyl Glutamate, Coptis Japonica Root Extract, Centella Asiatica Leaf Water, Beta-Glucan, Resveratrol, Hydrolyzed Hyaluronic Acid, Camellia Sinensis Leaf Water, Tocopherol, Madecassoside, Sodium DNA, Centella Asiatica Extract, Ceramide NP, Tannic Acid, Disodium EDTA, Sodium Phytate
Dimethicone
Nylon-12
Acrylates Crosspolymer
Enantia Chlorantha Bark Extract
Avena Sativa Kernel Extract
Camellia Sinensis Leaf Extract
Chrysanthemum Parthenium Extract
Oleanolic Acid
Sorbitan Isostearate
Caprylyl Glycol
Glyceryl Stearate Citrate
2-Hydroxyethyl Acrylate
Lecithin
Polysilicone-11
Polysorbate 60
Sodium Caprylate
Sodium Acrylates Copolymer
Laureth-8
Citric Acid
Phenoxyethanol
Potassium Sorbate
Sodium Benzoate
Water, Dimethicone, Propanediol, Butylene Glycol, Niacinamide, Nylon-12, Acrylates Crosspolymer, Sodium Hyaluronate, Enantia Chlorantha Bark Extract, Avena Sativa Kernel Extract, Camellia Sinensis Leaf Extract, Chrysanthemum Parthenium Extract, Glycerin, Oleanolic Acid, Sorbitan Isostearate, Caprylyl Glycol, Glyceryl Stearate Citrate, Hydrogenated Polydecene, 2-Hydroxyethyl Acrylate, 1,2-Hexanediol, Lecithin, Polysilicone-11, Polysorbate 60, Sodium Caprylate, Sodium Acrylates Copolymer, Laureth-8, Citric Acid, Phenoxyethanol, Potassium Sorbate, Sodium Benzoate
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
Humectant, drawing moisture into the skin
Emollient, helping to soften skin
Solvent, dispersing and stabilizing formulas
Preservative booster, enhancing the antimicrobial activity of other preservatives
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Hydrogenated Polydecene is a synthetic emollient. It forms a non-occlusive film on the skin's surface to provide a silky feel without being greasy.
In vivo studies in volunteers with atopic and dry skin showed no irritation or intolerance. The volunteers also saw a positive effect in dryness, scaling, and roughness after 28 days of use.
Concentrations up to 100% in guinea pig tests found it to be non-sensitizing and completely safe for use in cosmetics.
Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!