Dr. Althea 345 Relief Cream Versus Mizon Peptide Ampoule Cream

Dr. Althea 345 Relief Cream Versus Mizon Peptide Ampoule Cream

This calming moisturizer is formulated around Melaleuca Alternifolia Leaf Water and Niacinamide to calm redness and strengthen the skin barrier.

This anti-aging ampoule is formulated around Copper Tripeptide-1 and Adenosine to soften the look of wrinkles and strengthen the skin barrier.

What's inside

Key Ingredients

Benefits

Concerns

No concerns

Ingredients Side-by-side

Water

Melaleuca Alternifolia Leaf Water

Propanediol

Glycerin

1,2-Hexanediol

Hydrogenated Polydecene

Vinyldimethicone

C14-22 Alcohols

Niacinamide

Caprylic/Capric Triglyceride

Panthenol

Dicaprylyl Carbonate

Butylene Glycol

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Caprylyl Methicone

Polymethylsilsesquioxane

C12-20 Alkyl Glucoside

Hydroxyacetophenone

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Polyquaternium-51

Ethylhexylglycerin

Tromethamine

Sodium Hyaluronate

Sodium Stearoyl Glutamate

Coptis Japonica Root Extract

Centella Asiatica Leaf Water

Beta-Glucan

Resveratrol

Hydrolyzed Hyaluronic Acid

Camellia Sinensis Leaf Water

Tocopherol

Madecassoside

Sodium DNA

Centella Asiatica Extract

Ceramide NP

Tannic Acid

Disodium EDTA

Sodium Phytate

Water, Melaleuca Alternifolia Leaf Water, Propanediol, Glycerin, 1,2-Hexanediol, Hydrogenated Polydecene, Vinyldimethicone, C14-22 Alcohols, Niacinamide, Caprylic/Capric Triglyceride, Panthenol, Dicaprylyl Carbonate, Butylene Glycol, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Caprylyl Methicone, Polymethylsilsesquioxane, C12-20 Alkyl Glucoside, Hydroxyacetophenone, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Polyquaternium-51, Ethylhexylglycerin, Tromethamine, Sodium Hyaluronate, Sodium Stearoyl Glutamate, Coptis Japonica Root Extract, Centella Asiatica Leaf Water, Beta-Glucan, Resveratrol, Hydrolyzed Hyaluronic Acid, Camellia Sinensis Leaf Water, Tocopherol, Madecassoside, Sodium DNA, Centella Asiatica Extract, Ceramide NP, Tannic Acid, Disodium EDTA, Sodium Phytate

Stearic Acid

Neopentyl Glycol Diheptanoate

Cetearyl Olivate

Sorbitan Olivate

Hydrogenated Poly(C6-14 Olefin)

Cyclomethicone

Copper Tripeptide-1

Glyceryl Stearate

PEG-100 Stearate

Polyacrylate-13

Polyisobutene

Polysorbate 20

Cetearyl Alcohol

Cetearyl Glucoside

Dimethicone

Trehalose

Theobroma Cacao Extract

Caprylyl Glycol

Tropolone

Triethanolamine

Coptis Japonica Extract

Adenosine

Propylene Glycol

Hydrolyzed Extensin

Rubus Idaeus Fruit Extract

Biosaccharide Gum-1

Iris Florentina Root Extract

Hydrolyzed Wheat Protein

Prunus Amygdalus Dulcis Seed Extract

Lavandula Angustifolia Oil

Water, Stearic Acid, Neopentyl Glycol Diheptanoate, Cetearyl Olivate, Sorbitan Olivate, Hydrogenated Poly(C6-14 Olefin), Glycerin, Cyclomethicone, Butylene Glycol, Copper Tripeptide-1, Glyceryl Stearate, PEG-100 Stearate, Polyacrylate-13, Polyisobutene, Polysorbate 20, Cetearyl Alcohol, Cetearyl Glucoside, Dimethicone, Trehalose, Theobroma Cacao Extract, Caprylyl Glycol, Ethylhexylglycerin, Tropolone, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Triethanolamine, Coptis Japonica Extract, Adenosine, Propylene Glycol, Hydrolyzed Extensin, Rubus Idaeus Fruit Extract, Beta-Glucan, Biosaccharide Gum-1, Iris Florentina Root Extract, Hydrolyzed Wheat Protein, Prunus Amygdalus Dulcis Seed Extract, Lavandula Angustifolia Oil, Disodium EDTA

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Ammonium Acryloyldimethyltaurate/Vp Copolymer is a synthetically created polymer. It's used as a film-forming agent and used to thicken the consistency of products.

Think of it as a supportive ingredient that helps your gel-creams feel silky, "cloud cream-like", and spread evenly without being greasy.

The Cosmetic Ingredient Review (CIR) Expert Panel evaluated it (along with 22 other acryloyldimethyltaurate polymers) and concluded it's:

Due to its large molecular size, it sits on the surface of skin rather than penetrating it.

Beta-Glucan is a soluble polysaccharide (a chain of glucose sugars) sourced from the cells walls of oats, baker's yeast, mushrooms, and seaweed.

It's a rare ingredient that pulls double-duty as a heavy-duty hydrator and skin-soothing repair agent.

On the surface, it acts as a humectant that holds water in place and reduces moisture loss for a plumper, smoother feel, while its anti-inflammatory and antioxidant properties make it a great pick for calming redness or sensitive skin

The more interesting story is underneath:

Despite its large molecular size, oat beta-glucan has been shown to penetrate the epidermis and reach the dermis by slipping between skin cells. Here, it interacts with fibroblasts and macrophages to nudge collagen synthesis and support wound repair.

A small 2005 split-face clinical study of 27 subjects found topical beta-glucan produced measurable reductions in wrinkle depth, height, and roughness after 8 weeks of use.

It is worth noting the trial was small and the penetration testing used frozen, irradiated skin so the anti-aging data is encouraging rather than definitive.

This ingredient gets along with pretty much everything and is typically used around 0.1-1%.

Fungal acne: This ingredient is not a food source for the Malassezia yeast because it is a glucose polysaccharide with no fatty acid or ester component.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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