Dr. Althea Resveratrol 345NA Intensive Repair Cream Versus Cos De BAHA Peptide Complex Facial Cream with Matrixyl 3000 & Argireline

Dr. Althea Resveratrol 345NA Intensive Repair Cream Versus Cos De BAHA Peptide Complex Facial Cream with Matrixyl 3000 & Argireline

This barrier-repair moisturizer is formulated around Centella Asiatica Leaf Extract and Resveratrol to strengthen the skin barrier and calm redness.

This anti-aging moisturizer is formulated around Acetyl Hexapeptide-8 and Palmitoyl Tetrapeptide-7 to soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Propanediol

Glycerin

Cyclohexasiloxane

1,2-Hexanediol

Caprylic/Capric Triglyceride

Dicaprylyl Carbonate

Polyglycerin-3

Polyglyceryl-10 Stearate

Hydrogenated Polydecene

Laminaria Japonica Extract

Eclipta Prostrata Leaf Extract

Oenothera Biennis Flower Extract

Perilla Ocymoides Leaf Extract

Lavandula Angustifolia Flower Extract

Sargassum Fulvellum Extract

Centella Asiatica Leaf Extract

Gardenia Florida Fruit Extract

Calendula Officinalis Flower Extract

Melia Azadirachta Flower Extract

Houttuynia Cordata Extract

Melia Azadirachta Leaf Extract

Curcuma Longa Root Extract

Ocimum Sanctum Leaf Extract

Agave Tequilana Leaf Extract

Corallina Officinalis Extract

Hibiscus Sabdariffa Flower Extract

Sodium Hyaluronate

Hydrogenated Lecithin

Pelargonium Graveolens Flower Oil

Empetrum Nigrum Fruit Juice

Ammonium Acryloyldimethyltaurate/Vp Copolymer

C14-22 Alcohols

C12-20 Alkyl Glucoside

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Butylene Glycol

Polyquaternium-51

Tromethamine

Fructooligosaccharides

Adenosine

Beta-Glucan

Glycine Soja Sterols

Hydrolyzed Hyaluronic Acid

Resveratrol

Glucose

Oligopeptide-1

Ceramide NP

PEG-40 Castor Oil

Ethylhexylglycerin

Citronellol

Geraniol

Linalool

Water, Propanediol, Glycerin, Cyclohexasiloxane, 1,2-Hexanediol, Caprylic/Capric Triglyceride, Dicaprylyl Carbonate, Polyglycerin-3, Polyglyceryl-10 Stearate, Hydrogenated Polydecene, Laminaria Japonica Extract, Eclipta Prostrata Leaf Extract, Oenothera Biennis Flower Extract, Perilla Ocymoides Leaf Extract, Lavandula Angustifolia Flower Extract, Sargassum Fulvellum Extract, Centella Asiatica Leaf Extract, Gardenia Florida Fruit Extract, Calendula Officinalis Flower Extract, Melia Azadirachta Flower Extract, Houttuynia Cordata Extract, Melia Azadirachta Leaf Extract, Curcuma Longa Root Extract, Ocimum Sanctum Leaf Extract, Agave Tequilana Leaf Extract, Corallina Officinalis Extract, Hibiscus Sabdariffa Flower Extract, Sodium Hyaluronate, Hydrogenated Lecithin, Pelargonium Graveolens Flower Oil, Empetrum Nigrum Fruit Juice, Ammonium Acryloyldimethyltaurate/Vp Copolymer, C14-22 Alcohols, C12-20 Alkyl Glucoside, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Butylene Glycol, Polyquaternium-51, Tromethamine, Fructooligosaccharides, Adenosine, Beta-Glucan, Glycine Soja Sterols, Hydrolyzed Hyaluronic Acid, Resveratrol, Glucose, Oligopeptide-1, Ceramide NP, PEG-40 Castor Oil, Ethylhexylglycerin, Citronellol, Geraniol, Linalool

Aloe Barbadensis Leaf Extract

Niacinamide

Cetearyl Olivate

Cetearyl Alcohol

Glyceryl Stearate

Sorbitan Olivate

Panthenol

Acetyl Hexapeptide-8

Palmitoyl Tetrapeptide-7

Palmitoyl Tripeptide-1

Tocopheryl Acetate

Butyrospermum Parkii Butter

Argania Spinosa Kernel Oil

Caffeine

Allantoin

Dipotassium Glycyrrhizate

Squalane

Rosa Damascena Extract

Camellia Sinensis Leaf Extract

Melissa Officinalis Leaf Extract

Artemisia Vulgaris Extract

Sorbitan Isostearate

Polysorbate 60

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Aloe Barbadensis Leaf Extract, Propanediol, Caprylic/Capric Triglyceride, Niacinamide, 1,2-Hexanediol, Cetearyl Olivate, Cetearyl Alcohol, Glyceryl Stearate, Sorbitan Olivate, Panthenol, Acetyl Hexapeptide-8, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Tocopheryl Acetate, Butyrospermum Parkii Butter, Argania Spinosa Kernel Oil, Caffeine, Allantoin, Sodium Hyaluronate, Dipotassium Glycyrrhizate, Squalane, Ceramide NP, Adenosine, Rosa Damascena Extract, Lavandula Angustifolia Flower Extract, Camellia Sinensis Leaf Extract, Melissa Officinalis Leaf Extract, Artemisia Vulgaris Extract, Sorbitan Isostearate, Polysorbate 60, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.

The way it works is fairly well mapped out:

Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.

The clinical backing is pretty solid too.

A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.

A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.

On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.

This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.

Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.

Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.

Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.

In practice, that translates to a long shelf life and a consistently elegant skin feel.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.

Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.

This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.

This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.

Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.

Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.

This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.

A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.

Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.

Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.

Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.

Lavandula Angustifolia Flower Extract comes from the lavender plant.

Many components of lavender flowers are antioxidants, such as ferulic acid, caffeic acid, and several flavonoids.

Traditional Iranian folk medicine uses Lavender extract to help treat inflammation.

Lavender extract may have a scent.

It contains linalool, a known allergen. However, lavender extract contains less linalool than lavender essential oil.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

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