Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Dr.Ceuracle Cica Regen Vegan Sun SPF 50+ PA++++ Versus Beauty of Joseon Relief Sun : Rice + Probiotics SPF 50+ PA++++

Dr.Ceuracle Cica Regen Vegan Sun SPF 50+ PA++++ Versus Beauty of Joseon Relief Sun : Rice + Probiotics SPF 50+ PA++++ This chemical sunscreen covers the full UV range and blocks ~98% of UVB at SPF 50. What's inside Key Ingredients Benefits Concerns Ingredients

Dr.Ceuracle Cica Regen Vegan Sun SPF 50+ PA++++ Versus Beauty of Joseon Relief Sun : Rice + Probiotics SPF 50+ PA++++

This chemical sunscreen covers the full UV range and blocks ~98% of UVB at SPF 50.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Dibutyl Adipate

Propanediol

Alcohol Denat.

Ethylhexyl Triazone

Terephthalylidene Dicamphor Sulfonic Acid

Glycerin

Niacinamide

Tromethamine

Polyglyceryl-3 Distearate

1,2-Hexanediol

Diethylamino Hydroxybenzoyl Hexyl Benzoate

Cetearyl Alcohol

Caprylyl Methicone

Pentylene Glycol

Polysilicone-15

Polymethylsilsesquioxane

Palmitic Acid

Stearic Acid

Glyceryl Stearate

Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine

Potassium Cetyl Phosphate

Methylpropanediol

Polyether-1

Carbomer

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Glyceryl Stearate Citrate

Rosmarinus Officinalis Leaf Oil

Polyquaternium-51

Ethylhexylglycerin

Adenosine

Centella Asiatica Extract

Myristic Acid

Butylene Glycol

Actinidia Arguta Fruit Extract

Madecassoside

Hibiscus Sabdariffa Flower Extract

Madecassic Acid

Asiaticoside

Nelumbium Speciosum Flower Extract

Asiatic Acid

Tocopherol

Water, Dibutyl Adipate, Propanediol, Alcohol Denat., Ethylhexyl Triazone, Terephthalylidene Dicamphor Sulfonic Acid, Glycerin, Niacinamide, Tromethamine, Polyglyceryl-3 Distearate, 1,2-Hexanediol, Diethylamino Hydroxybenzoyl Hexyl Benzoate, Cetearyl Alcohol, Caprylyl Methicone, Pentylene Glycol, Polysilicone-15, Polymethylsilsesquioxane, Palmitic Acid, Stearic Acid, Glyceryl Stearate, Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine, Potassium Cetyl Phosphate, Methylpropanediol, Polyether-1, Carbomer, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Glyceryl Stearate Citrate, Rosmarinus Officinalis Leaf Oil, Polyquaternium-51, Ethylhexylglycerin, Adenosine, Centella Asiatica Extract, Myristic Acid, Butylene Glycol, Actinidia Arguta Fruit Extract, Madecassoside, Hibiscus Sabdariffa Flower Extract, Madecassic Acid, Asiaticoside, Nelumbium Speciosum Flower Extract, Asiatic Acid, Tocopherol

Methylene Bis-Benzotriazolyl Tetramethylbutylphenol

Coco-Caprylate/Caprate

Diethylhexyl Butamido Triazone

Oryza Sativa Extract

Oryza Sativa Germ Extract

Camellia Sinensis Leaf Extract

Lactobacillus/Pumpkin Ferment Extract

Bacillus/Soybean Ferment Extract

Saccharum Officinarum Extract

Macrocystis Pyrifera Extract

Cocos Nucifera Fruit Extract

Panax Ginseng Root Extract

Monascus/Rice Ferment

Behenyl Alcohol

Poly C10-30 Alkyl Acrylate

Polyglyceryl-3 Methylglucose Distearate

Decyl Glucoside

Sodium Stearoyl Glutamate

Polyacrylate Crosspolymer-6

Xanthan Gum

T-Butyl Alcohol

Lactobacillus/Rice Ferment

Aspergillus Ferment

Saccharomyces/Rice Ferment Filtrate

Water, Dibutyl Adipate, Propanediol, Diethylamino Hydroxybenzoyl Hexyl Benzoate, Polymethylsilsesquioxane, Ethylhexyl Triazone, Niacinamide, Methylene Bis-Benzotriazolyl Tetramethylbutylphenol, Coco-Caprylate/Caprate, Caprylyl Methicone, Diethylhexyl Butamido Triazone, Glycerin, 1,2-Hexanediol, Butylene Glycol, Oryza Sativa Extract, Oryza Sativa Germ Extract, Camellia Sinensis Leaf Extract, Lactobacillus/Pumpkin Ferment Extract, Bacillus/Soybean Ferment Extract, Saccharum Officinarum Extract, Macrocystis Pyrifera Extract, Cocos Nucifera Fruit Extract, Panax Ginseng Root Extract, Monascus/Rice Ferment, Behenyl Alcohol, Poly C10-30 Alkyl Acrylate, Polyglyceryl-3 Methylglucose Distearate, Decyl Glucoside, Tromethamine, Carbomer, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Sodium Stearoyl Glutamate, Polyacrylate Crosspolymer-6, Adenosine, Xanthan Gum, T-Butyl Alcohol, Tocopherol, Lactobacillus/Rice Ferment, Aspergillus Ferment, Saccharomyces/Rice Ferment Filtrate, Pentylene Glycol, Ethylhexylglycerin

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products.

As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied.

It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin.

A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record.

Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.

The way it works is fairly well mapped out:

Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.

The clinical backing is pretty solid too.

A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.

A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.

On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.

This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.

Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Caprylyl Methicone is a synthetic and lightweight silicone fluid. It gives products a silky, dry-touch finish without the heaviness of pure oils.

Though the EU CosIng Database lists this ingredient as a skin conditioner, it is also used for sensory reasons. It spreads easily, cuts greasiness, and reduces tackiness.

This ingredient is volatile which means it will mostly evaporate (but it evaporates slower than older cyclomethicones, like Cyclotetrasiloxane).

Typical concentration ranges from 1-30% depending on if it's being used to tweak the feel of a product or acting as the main emollient.

Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.

Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.

It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.

Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.

A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.

Dibutyl Adipate is a lightweight, oil-soluble ester that acts as an emollient and solvent. It helps products spread more easily and leaves a soft, silky, dry-touch finish without being greasy.

You'll likely see this ingredient in sunscreens because it does a nice job dissolving UV filters and keeping them evenly distributed.

This ingredient has been found to be safe as used in cosmetics, wasn't a skin or eye irritant in clinical patch testing, and wasn't phototoxic.

In a clinical comedogenicity test, this ingredient tested negative so it isn't likely to clog pores.

Typical use levels are about 5-8% for sunscreens + nail products, but can range from 0.005%-8% depending on the product.

Diethylamino Hydroxybenzoyl Hexyl Benzoate (DHHB) is a chemical UV-A absorber. It is formulated for high UVA protection (320-400 nm).

DHHB is well-liked for:

DHHB has been approved by the EU, Japan, Taiwan, and South America for use up to 10%. Unfortunately, it has not been approved for use in the US or Canada due to slow regulatory processes.

This ingredient is soluble in oils, fats, and lipids.

Ethylhexyl Triazone (aka Octyl Triazone) is an oil-soluble organic UVB filter. It has peak absorption around 314 nm, right in the middle of the UVB range.

This ingredient is described as one of the most effective UVB filters available and small concentrations are enough to deliver a high SPF thanks to its strong UV absorbing power.

Formulators love it for its stability; its ability to filter UV stays practically unchanged even under intense radiation and it can also help boost the photostability of less stable filters like avobenzone.

It's also a great pick for water resistant products because it's insoluble in water and has a good affinity for keratin.

Because it's a big, heavy molecule, the European Scientific Committee has found to to have very low dermal penetration and negative results for allergenicity.

In vitro testing also showed a low absorption rate and clean results on irritation.

Typical use levels are 1-5% with 5% being the maximum in the EU, Japan, and other markets that allow it. However, this ingredient is not approved yet in the US or Canada.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:

Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.

On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.

Typical use levels in a formula run about 1-5%.

Polymethylsilsesquioxane is a silicone used as a film forming agent.

When applied to the skin, this ingredient creates an invisible film on the surface. This film still allows oxygen to pass through, but prevents moisture from escaping. This can help condition and hydrate the skin. It also leaves a silky feel when applied.

Polymethylsilsesquioxane has not been shown to clog pores. It has been deemed safe to use up to 55%, but most cosmetics use much less.

If you have concerns about using this ingredient, we recommend speaking with a professional.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Tocopherol is a fat-soluble antioxidant known as Vitamin E.

You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.

Tromethamine (aka THAM) is a synthetic amino acid that shows up in skincare as a helper ingredient.

It functions as a pH adjuster to help neutralize acidic ingredients and set a formula's pH to the right spot.

This matters a lot because a lot of actives (like vitamin C) needs a specific pH to work well and feel comfortable on skin.

Concentration use ranges from 0.1-1.0% depending on the formula.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 031,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
  4. 04It is a:
  5. 05Humectant, drawing moisture into the skin
  6. 06Emollient, helping to soften skin
  7. 07Solvent, dispersing and stabilizing formulas
  8. 08Preservative booster, enhancing the antimicrobial activity of other preservatives
  9. 09Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
  10. 10Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
  11. 11Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
  12. 12This ingredient is also known as shea butter. It is a plant-derived extract from the nuts of the Africa shea tree and one of the most well-studied emollients.
  13. 13Because it has a high concentration of fatty acids (primarily oleic, stearic, and linoleic) it is able to form a protective barrier on the skin's surface. This helps seal in moisture and prevents transepidermal water loss (TEWL).
  14. 14In vitro research found an increase in skin hydration by 58% and a decrease in TEWL by 37.8% after 24 hours of applying this ingredient (pretty impressive for a single ingredient!).
  15. 15Besides hydration, shea butter also contains triterpenes that have anti-inflammatory potential. In particule, lupeol cinnamate has shown the highest anti-inflammatory activity in vivo.
  16. 16Shea butter also contains vitamins A and E which may contribute to antioxidant activity.
  17. 17While Shea Butter has an SPF rating of about 3-4, it is not a sunscreen replacement.
  18. 18This ingredient may not be fungal acne safe because its fatty acids fall within the C11-C24 range that the Malassezia yeast can metabolize.
  19. 19Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.
  20. 20Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.
Source · skinsort.com
02

Product index

Related product references

03

Comparison edit

Read side by side