Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Dr.G R.E.D Blemish Clear Soothing Toner Versus Torriden Dive-In Low-Molecular Hyaluronic Acid Serum

Dr.G R.E.D Blemish Clear Soothing Toner Versus Torriden Dive-In Low-Molecular Hyaluronic Acid Serum This calming toner is formulated around Niacinamide and Centella Asiatica Extract to calm redness and clear breakouts. This hydrating serum is formulated around

Dr.G R.E.D Blemish Clear Soothing Toner Versus Torriden Dive-In Low-Molecular Hyaluronic Acid Serum

This calming toner is formulated around Niacinamide and Centella Asiatica Extract to calm redness and clear breakouts.

This hydrating serum is formulated around Panthenol and Hydrolyzed Hyaluronic Acid to hydrate skin and strengthen the skin barrier.

What's inside

Key Ingredients

Benefits

Concerns

No concerns

Ingredients Side-by-side

Water

Dipropylene Glycol

Propanediol

Pentylene Glycol

Niacinamide

Butylene Glycol

Glycerin

Portulaca Oleracea Extract

Centella Asiatica Extract

Ficus Carica Fruit Extract

Salix Alba Bark Extract

Saccharum Officinarum Extract

Malus Domestica Fruit Extract

Aloe Ferox Leaf Extract

Hydrogenated Lecithin

Panthenol

Raffinose

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Tromethamine

Disodium EDTA

Betaine

Beta-Glucan

Madecassoside

Ceramide NP

Madecassic Acid

Asiaticoside

Asiatic Acid

Ethylhexylglycerin

1,2-Hexanediol

Caprylyl Glycol

Water, Dipropylene Glycol, Propanediol, Pentylene Glycol, Niacinamide, Butylene Glycol, Glycerin, Portulaca Oleracea Extract, Centella Asiatica Extract, Ficus Carica Fruit Extract, Salix Alba Bark Extract, Saccharum Officinarum Extract, Malus Domestica Fruit Extract, Aloe Ferox Leaf Extract, Hydrogenated Lecithin, Panthenol, Raffinose, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tromethamine, Disodium EDTA, Betaine, Beta-Glucan, Madecassoside, Ceramide NP, Madecassic Acid, Asiaticoside, Asiatic Acid, Ethylhexylglycerin, 1,2-Hexanediol, Caprylyl Glycol

Sodium Hyaluronate Crosspolymer

Hydrolyzed Hyaluronic Acid

Sodium Hyaluronate

Sodium Acetylated Hyaluronate

Hydrolyzed Sodium Hyaluronate

Allantoin

Ectoin

Glycyrrhiza Glabra Root Extract

2,3-Butanediol

Trehalose

Hamamelis Virginiana Leaf Extract

Malachite Extract

Cholesterol

Glyceryl Acrylate/Acrylic Acid Copolymer

Pvm/Ma Copolymer

Polyglyceryl-10 Laurate

Xanthan Gum

Carbomer

Scutellaria Baicalensis Root Extract

Paeonia Suffruticosa Root Extract

Water, Butylene Glycol, Glycerin, Dipropylene Glycol, 1,2-Hexanediol, Panthenol, Sodium Hyaluronate Crosspolymer, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate, Sodium Acetylated Hyaluronate, Hydrolyzed Sodium Hyaluronate, Allantoin, Ectoin, Glycyrrhiza Glabra Root Extract, 2,3-Butanediol, Trehalose, Betaine, Propanediol, Portulaca Oleracea Extract, Hamamelis Virginiana Leaf Extract, Madecassoside, Madecassic Acid, Ceramide NP, Beta-Glucan, Malachite Extract, Cholesterol, Pentylene Glycol, Glyceryl Acrylate/Acrylic Acid Copolymer, Pvm/Ma Copolymer, Polyglyceryl-10 Laurate, Xanthan Gum, Tromethamine, Carbomer, Ethylhexylglycerin, Scutellaria Baicalensis Root Extract, Paeonia Suffruticosa Root Extract

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Beta-Glucan is a soluble polysaccharide (a chain of glucose sugars) sourced from the cells walls of oats, baker's yeast, mushrooms, and seaweed.

It's a rare ingredient that pulls double-duty as a heavy-duty hydrator and skin-soothing repair agent.

On the surface, it acts as a humectant that holds water in place and reduces moisture loss for a plumper, smoother feel, while its anti-inflammatory and antioxidant properties make it a great pick for calming redness or sensitive skin

The more interesting story is underneath:

Despite its large molecular size, oat beta-glucan has been shown to penetrate the epidermis and reach the dermis by slipping between skin cells. Here, it interacts with fibroblasts and macrophages to nudge collagen synthesis and support wound repair.

A small 2005 split-face clinical study of 27 subjects found topical beta-glucan produced measurable reductions in wrinkle depth, height, and roughness after 8 weeks of use.

It is worth noting the trial was small and the penetration testing used frozen, irradiated skin so the anti-aging data is encouraging rather than definitive.

This ingredient gets along with pretty much everything and is typically used around 0.1-1%.

Fungal acne: This ingredient is not a food source for the Malassezia yeast because it is a glucose polysaccharide with no fatty acid or ester component.

Betaine is a humectant. Like hyaluronic acid, it helps attract and retain moisture in the skin. It’s known for being gentle and for helping the skin maintain balanced hydration.

Betaine is mainly used to improve hydration and support calmer skin. It helps skin cells regulate water balance because it functions as an osmolyte.

Some studies suggest betaine may support making skin tone more even.

Fun fact: Betaine naturally exists in the skin and the body. In cosmetic products, it can be either plant-derived (most commonly from sugar beets) or synthetically produced for consistency and stability.

Betaine is also known as trimethylglycine.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.

Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.

This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.

A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.

Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.

Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.

Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.

Dipropylene Glycol is a synthetically created humectant, stabilizer, and solvent.

This ingredient helps:

Dipropylene glycol is technically an alcohol, but it belongs to the glycol family (often considered part of the ‘good’ alcohols). This means it is hydrating and gentle on skin unlike drying solvent alcohols like denatured alcohol.

As a masking agent, Dipropylene Glycol can be used to cover the smell of other ingredients. However, it does not have a scent.

Studies show Dipropylene Glycol is considered safe to use in skincare.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Madecassic Acid is one of the four star actives in Centella Asiatica. In skincare, it earns its keep as a calming and repairing ingredient.

It works through the same core pathways as the rest of the centella family.

First, it turns down inflammation so it helps with things like redness and general upset skin.

Second, it acts as an antioxidant which means it helps protect skin from daily stress and damage.

And third, it nudges the skin to make more collagen and rebuild its support structure.

That combination is why the whole Centella family is known for calming skin, strengthening the barrier, fading redness, and giving anti-aging benefits.

It's worth being honest about the evidence here; a lot of the strongest data is on the full extract or a Madecassoside/Asiaticoside rather than Madecassic Acid alone. Reviewers also note more long-term clinical trials are needed to confirm the full potential.

Concentration-wise, this ingredient is rarely used pure and usually shows up as part of a standardized centella extract where reported content ranges from 0.02-3.06%.

Finished products typically run somewhere in the 0.1-10% range depending on the format.

In real-world tolerance tests, a repeat-insult patch test on an eye lotion with 0.2% Centella extract showed no irritation or allergic contact dermatitis in 54 subjects. And a mascara with 0.5% Madecassoside caused neither irritation nor sensitization in 109 subjects.

Allergy risk is very low, but not zero. Centella and its constituents are classified as weak contact sensitizers and some rare cases of allergic contact dermatitis exist.

Madecassoside is one of four active compounds found in Centella asiatica and is one of the main reasons Centella is so effective at calming irritated skin and supporting the moisture barrier.

There's a solid body of peer-reviewed research backing Madecassoside for several skin benefits. Studies have found:

Madecassoside pairs well with other hydrating or antioxidant ingredients like Ascorbic Acid or Hyaluronic Acid.

Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.

There are two forms of panthenol: D and L.

D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.

Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):

Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.

This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.

Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.

This ingredient is also referred to as pro-vitamin B5.

Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:

Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.

On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.

Typical use levels in a formula run about 1-5%.

This extract comes from Purslane, a succulent. It has anti-inflammatory, antioxidant, and hydrating properties.

Purslane is very nutritious. It contains omega-3 fatty acids, NMFs, many vitamins, minerals, and antioxidants. The vitamins found in purslane include: Vitamin C, Vitamin A, and Vitamin E.

Fun fact: Purslane is a succulent with an extensive habitat. It is used in traditional Korean medicine to treat irritated skin.

Nowadays, purslane is becoming a superfood due to its highly nutritious content.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Tromethamine (aka THAM) is a synthetic amino acid that shows up in skincare as a helper ingredient.

It functions as a pH adjuster to help neutralize acidic ingredients and set a formula's pH to the right spot.

This matters a lot because a lot of actives (like vitamin C) needs a specific pH to work well and feel comfortable on skin.

Concentration use ranges from 0.1-1.0% depending on the formula.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 031,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
  4. 04It is a:
  5. 05Humectant, drawing moisture into the skin
  6. 06Emollient, helping to soften skin
  7. 07Solvent, dispersing and stabilizing formulas
  8. 08Preservative booster, enhancing the antimicrobial activity of other preservatives
  9. 09Beta-Glucan is a soluble polysaccharide (a chain of glucose sugars) sourced from the cells walls of oats, baker's yeast, mushrooms, and seaweed.
  10. 10It's a rare ingredient that pulls double-duty as a heavy-duty hydrator and skin-soothing repair agent.
  11. 11On the surface, it acts as a humectant that holds water in place and reduces moisture loss for a plumper, smoother feel, while its anti-inflammatory and antioxidant properties make it a great pick for calming redness or sensitive skin
  12. 12The more interesting story is underneath:
  13. 13Despite its large molecular size, oat beta-glucan has been shown to penetrate the epidermis and reach the dermis by slipping between skin cells. Here, it interacts with fibroblasts and macrophages to nudge collagen synthesis and support wound repair.
  14. 14A small 2005 split-face clinical study of 27 subjects found topical beta-glucan produced measurable reductions in wrinkle depth, height, and roughness after 8 weeks of use.
  15. 15It is worth noting the trial was small and the penetration testing used frozen, irradiated skin so the anti-aging data is encouraging rather than definitive.
  16. 16This ingredient gets along with pretty much everything and is typically used around 0.1-1%.
  17. 17Fungal acne: This ingredient is not a food source for the Malassezia yeast because it is a glucose polysaccharide with no fatty acid or ester component.
  18. 18Betaine is a humectant. Like hyaluronic acid, it helps attract and retain moisture in the skin. It’s known for being gentle and for helping the skin maintain balanced hydration.
  19. 19Betaine is mainly used to improve hydration and support calmer skin. It helps skin cells regulate water balance because it functions as an osmolyte.
  20. 20Some studies suggest betaine may support making skin tone more even.
Source · skinsort.com
02

Product index

Related product references

Product

ABI Skincare Hyaluronic Acid Serum

ABI Skincare Hyaluronic Acid Serum ABI Skincare Hyaluronic Acid Serum ingredients explained: Water, Glycerin, Trehalose, Propylene Glycol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Trie…

Source: incidecoder.comView reference →
03

Comparison edit

Read side by side

04

Ask the journal

Related questions

01Is Serum Good for All Skin Types?

Serums are a form of skincare that can be added to any routine no matter what your skin type is. All skin types can benefit from the use of a serum since there are so many different formulations that can target specific skincare concerns. “Serums are used for hydration,to aid [or] maintain the skin barrier, or treat skin issues like acne or rosacea,” says Dr. Lewis. The type of serum that you may use should depend on the skin issue you’re trying to target. Think of serums as a treatment for the skin. “Some serums can reverse damage and help prevent free radicals that cause the signs of aging skin,” adds Dr. Lewis.

Source · www.skincare.com
02When and How to Use Hyaluronic Acid in Your Routine

Products with hyaluronic acid can be used in the morning or at night (or both!). Applying the hydrating ingredient at night will restore your skin’s resilience while you sleep, and applying it in the morning will leave your skin feeling plump, hydrated and ready for makeup. Hyaluronic acid is great at providing topical hydration when it’s introduced into a balanced skincare routine. According to Dr. King, it’s important to pair your hyaluronic acid products with an emollient or occlusive moisturizer to lock in hydration.

Source · www.skincare.com