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Skin science article

Dr.G Royal Black Snail Cream Versus iUNIK Black Snail Restore Cream

Dr.G Royal Black Snail Cream Versus iUNIK Black Snail Restore Cream This barrier-repair moisturizer is formulated around Snail Secretion Filtrate and Niacinamide to strengthen the skin barrier and hydrate skin. This barrier-repair moisturizer is formulated aro

Dr.G Royal Black Snail Cream Versus iUNIK Black Snail Restore Cream

This barrier-repair moisturizer is formulated around Snail Secretion Filtrate and Niacinamide to strengthen the skin barrier and hydrate skin.

This barrier-repair moisturizer is formulated around Centella Asiatica Leaf Water and Snail Extract to strengthen the skin barrier and calm redness.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Snail Secretion Filtrate

Dipropylene Glycol

Glycerin

Cyclohexasiloxane

Cetearyl Alcohol

Caprylic/Capric Triglyceride

Triethylhexanoin

Niacinamide

Hydrogenated Polydecene

Hydrogenated Polyisobutene

Hydrogenated Poly(C6-14 Olefin)

Beeswax

Hydrolyzed Royal Jelly Protein

Honey Extract

1,2-Hexanediol

Palmitic Acid

Stearic Acid

Cetearyl Glucoside

Glycosyl Trehalose

Polyglyceryl-2 Stearate

Vinyldimethicone

Cetearyl Olivate

Glyceryl Stearate

Butylene Glycol

Hydrogenated Starch Hydrolysate

Butyrospermum Parkii Butter

Stearyl Alcohol

Caprylyl Glycol

Sorbitan Olivate

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Dioscorea Japonica Root Extract

Arginine

Carbomer

Hydrolyzed Corn Starch

Xanthan Gum

Adenosine

Hydrogenated Lecithin

Hexylglycerin

Beta-Glucan

Caramel

Phenethyl Alcohol

Sucrose

Sorbitan Isostearate

Portulaca Oleracea Extract

Pearl Powder

Phytic Acid

Tranexamic Acid

Maltodextrin

Myristic Acid

Glucose

Centella Asiatica Extract

Phellinus Linteus Extract

Pentylene Glycol

Zymomonas Ferment Extract

Parfum

Water, Snail Secretion Filtrate, Dipropylene Glycol, Glycerin, Cyclohexasiloxane, Cetearyl Alcohol, Caprylic/Capric Triglyceride, Triethylhexanoin, Niacinamide, Hydrogenated Polydecene, Hydrogenated Polyisobutene, Hydrogenated Poly(C6-14 Olefin), Beeswax, Hydrolyzed Royal Jelly Protein, Honey Extract, 1,2-Hexanediol, Palmitic Acid, Stearic Acid, Cetearyl Glucoside, Glycosyl Trehalose, Polyglyceryl-2 Stearate, Vinyldimethicone, Cetearyl Olivate, Glyceryl Stearate, Butylene Glycol, Hydrogenated Starch Hydrolysate, Butyrospermum Parkii Butter, Stearyl Alcohol, Caprylyl Glycol, Sorbitan Olivate, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Dioscorea Japonica Root Extract, Arginine, Carbomer, Hydrolyzed Corn Starch, Xanthan Gum, Adenosine, Hydrogenated Lecithin, Hexylglycerin, Beta-Glucan, Caramel, Phenethyl Alcohol, Sucrose, Sorbitan Isostearate, Portulaca Oleracea Extract, Pearl Powder, Phytic Acid, Tranexamic Acid, Maltodextrin, Myristic Acid, Glucose, Centella Asiatica Extract, Phellinus Linteus Extract, Pentylene Glycol, Zymomonas Ferment Extract, Parfum

Centella Asiatica Leaf Water

Glycereth-26

Simmondsia Chinensis Seed Oil

Camellia Japonica Seed Oil

Sorbitan Sesquioleate

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Snail Extract

Sodium Polyacrylate

Disodium EDTA

Ethylhexylglycerin

Scutellaria Baicalensis Root Extract

Polygonum Cuspidatum Root Extract

Dipotassium Glycyrrhizate

Camellia Sinensis Leaf Extract

Cynanchum Atratum Extract

Chamomilla Recutita Flower Extract

Rosmarinus Officinalis Leaf Extract

Water, Centella Asiatica Leaf Water, Butylene Glycol, Butyrospermum Parkii Butter, Cetearyl Alcohol, Glycereth-26, 1,2-Hexanediol, Cetearyl Olivate, Simmondsia Chinensis Seed Oil, Camellia Japonica Seed Oil, Sorbitan Olivate, Beeswax, Sorbitan Sesquioleate, Vinyldimethicone, Glyceryl Stearate, Arginine, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Snail Extract, Xanthan Gum, Sodium Polyacrylate, Adenosine, Disodium EDTA, Ethylhexylglycerin, Centella Asiatica Extract, Scutellaria Baicalensis Root Extract, Polygonum Cuspidatum Root Extract, Dipotassium Glycyrrhizate, Camellia Sinensis Leaf Extract, Pentylene Glycol, Caprylyl Glycol, Cynanchum Atratum Extract, Chamomilla Recutita Flower Extract, Rosmarinus Officinalis Leaf Extract

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.

The way it works is fairly well mapped out:

Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.

The clinical backing is pretty solid too.

A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.

A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.

On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.

This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.

Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.

Arginine is a semi-essential amino acid. This just means our bodies can product a bit on its own, but sometimes needs a little boost from food sources.

It is a part of your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.

Here's an interesting thing about Arginine: your skin converts it into urea through the Krebs-Henseleit urea cycle. Urea is one of the most effective humectants your skin naturally produces.

A clinical study showed applying 2.5% arginine hydrochloride to atopic dermatitis skin showed significant urea levels in the stratum corneum and improved moisture in just four weeks.

Arginine is also a precursor to nitric oxide; nitric oxide improves microcirculation and supports wound healing and collagen synthesis.

One study found that an amino acid complex containing Arginine reduced skin irritation, improved hydration, and accelerated skin repair in clinical / in-vivo studies.

Arginine itself is an amino acid and not a fatty acid, oil, or ester. On its own, it's not a direct food source for Malassezia, or the yeast that causes fungal acne.

Beeswax is natural wax produced by honey bees to build their honeycomb.

Because it forms a protective layer on your skin, it can help lock in moisture and reduce water loss. It is also widely used as a thickener and emulsifier in lip balms and lotions. Research suggests beeswax containing moisturizers can support skin barrier integrity.

In comedogenic testing, Beeswax scored a 0-2, which is on the low end. Whether or not a product clogs your pores really comes down to the formula as a whole (not any single ingredient on its own).

Cera Alba is the white, bleached form of this ingredient.

Just so you know, beeswax is not vegan since it is animal-derived. It cannot be removed with water, but can be taken off with an oil cleanser.

People with a known Propolis allergy also report to have reactions from beeswax.

Beeswax's wax esters are derived primarily from palmitic and oleic acid (C16 and C18:1). Both of these fall within the C11-C24 feeding window.

The Malassezia yeast can potentially cleave these esters and release usable fatty acids, so this ingredient may not be fungal acne safe. However, not everyone will react to this ingredient.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

This ingredient is also known as shea butter. It is a plant-derived extract from the nuts of the Africa shea tree and one of the most well-studied emollients.

Because it has a high concentration of fatty acids (primarily oleic, stearic, and linoleic) it is able to form a protective barrier on the skin's surface. This helps seal in moisture and prevents transepidermal water loss (TEWL).

In vitro research found an increase in skin hydration by 58% and a decrease in TEWL by 37.8% after 24 hours of applying this ingredient (pretty impressive for a single ingredient!).

Besides hydration, shea butter also contains triterpenes that have anti-inflammatory potential. In particule, lupeol cinnamate has shown the highest anti-inflammatory activity in vivo.

Shea butter also contains vitamins A and E which may contribute to antioxidant activity.

While Shea Butter has an SPF rating of about 3-4, it is not a sunscreen replacement.

This ingredient may not be fungal acne safe because its fatty acids fall within the C11-C24 range that the Malassezia yeast can metabolize.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Centella Asiatica Extract (Centella) is one of the most researched botanical extracts in skincare with decades of studies backing its effects on inflammation, collagen, and the skin barrier.

That research keeps pointing back to the same four triterpenoid saponins: Asiaticoside, Madecassoside, Asiatic Acid, and Madecassic Acid.

These compounds allow centella to dial back inflammation, encourage the skin to build and hold onto collagen, support the barrier and hydration, and bring solid antioxidant activity to protect against signs of aging.

Centella also carries a nice supporting cast of Vitamin A, vitamin C, several B vitamins, and amino acids. Put it all together and you get an ingredient that soothes, hydrates, and protects, all at once.

Most of centella's magic comes from the four big compounds (Asiaticoside, Madecassoside, Asiatic Acid, and Madecassic Acid). These are the actives doing the heavy lifting in almost every centella study.

Here is the short version of what they do in the skin:

So it is not just soothing for the sake of soothing. Centella calms the skin AND helps it rebuild.

Just FYI, not all centella on an ingredient list is the same. What you are getting actually depends on the extract:

Fun fact on the ratios: the leaves tend to be richest in Madecassoside and Asiaticoside, and lower in the two acids. The exact amounts shift with where the plant is grown and how it is processed. This means purity really does vary brand to brand.

Centella is one of the most easygoing actives out there.

It layers well with basically everything: niacinamide, hyaluronic acid, peptides, and vitamin C, and also pairs nicely with stronger actives like retinoids and exfoliating acids where it can help take the edge off irritation.

On the safety side, centella and its triterpenes are classified as weak sensitizers, meaning allergic reactions are possible but uncommon.

Patch tests at 1% and 5% came back negative in test panels, and creams at typical use levels did not cause allergic reactions across large groups of people.

But as with any new active, a patch test is still a smart move for very reactive skin.

Centella is widely used because it is effective at low percentages. For context, human safety testing found no meaningful irritation from creams containing centella extract at everyday use levels (the tested amounts were well under 1%).

The irritancy threshold in animal testing was also above 30% (so real-world formulas sit far below anything concerning).

In collagen lab studies, higher concentrations drove more collagen synthesis, so serums built around centella tend to feature it more prominently.

Bottom line: you will find centella working nicely anywhere from a fraction of a percent up to hero-ingredient levels depending on whether it is a supporting soother or the main event.

Fun fact: Centella has been used as a medicine and in food for many centuries. As a medicine, it is used to treat burns, scratches, and wounds.

Cetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier.

Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient.

It plays several roles in a formula:

Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products.

Multiple assessments have found it to be non-irritating and non-sensitizing to most people.

However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers.

Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy.

Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans.

Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients.

This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain lengths that fall within the range that Malassezia can metabolize.

A 2019 study has also observed Malassezia growth in the presence of this ingredient, confirming it to be not-fungal acne safe.

Cetearyl Olivate is a plant-derived emulsifier and texture enhancer. It helps keep the oil and water phases from separating so your formulas stay stable.

You'll likely see it combined with Sorbitan Olivate (together sold as the trade name Olivem 1000). This combination generates a liquid crystal structure that closely resemble the lipid organization of the stratum corneum.

These "skin-like" liquid crystals improve skin barrier integrity and promote the delivery of actives into the skin.

This ingredient is well-tolerated and has no significant sensitization data.

Because it is derived from the fatty acids in olive oil, this ingredient may not be fungal acne safe.

Glyceryl Stearate is made by reacting glycerin with stearic acid (typically sourced from plant oils like palm or coconut). It's an emulsifier, emollient, and mild occlusive.

Emulsifiers help ingredients like oil and water stay mixed so your formula stays nicely blended and uniform in texture.

This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototoxic, and non-photoallergenic.

A close cousin of this ingredient is Glyceryl Stearate SE ("self-emulsifying"). This just has a small amount of sodium or potassium stearate added so it can emulsify without a co-emulsifier.

Since this ingredient is an ester of a C18 fatty acid, it may not be fungal acne safe. The Malassezia yeast can potentially metabolize within the C11-C24 range.

Fun fact: The human body also creates Glyceryl Stearate naturally.

Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:

Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.

On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.

Typical use levels in a formula run about 1-5%.

Sorbitan Olivate is created from the fatty acids in olive oil and sorbitol.

This ingredient is an oil in water emulsifier. It helps stabilize a product by preventing oils and waters from separating. Sorbitan Olivate also helps hydrate the skin.

This ingredient is also known as part of Olivem 1000, with Cetearyl Olivate being the other part.

According to a manufacturer, this ingredient helps preserve the natural microbiome of skin. Having a healthy microbiome helps keep our skin healthy and protects against harmful bacteria.

Please note, having a healthy microbiome is different from fungal acne; a healthy microbiome includes small amounts of yeast that normally live on your skin without causing problems.

Fungal acne happens when one type of yeast (Malassezia) grows out of control. This is usually because it's feeding on certain oils or fatty acids. Due to the olive oil base, this ingredient may not be fungal acne safe.

Vinyldimethicone is a type of silicone.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

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Product index

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Comparison edit

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