Skin science article
Dr. Jart+ Ceramidin™ Skin Barrier Moisturizing Cream Versus Paula's Choice Clinical Ceramide-Enriched Firming Moisturizer
Dr. Jart+ Ceramidin™ Skin Barrier Moisturizing Cream Versus Paula's Choice Clinical Ceramide-Enriched Firming Moisturizer This barrier-repair moisturizer is formulated around Ceramide NP and Panthenol to strengthen the skin barrier and hydrate skin. This anti-
Dr. Jart+ Ceramidin™ Skin Barrier Moisturizing Cream Versus Paula's Choice Clinical Ceramide-Enriched Firming Moisturizer
This barrier-repair moisturizer is formulated around Ceramide NP and Panthenol to strengthen the skin barrier and hydrate skin.
This anti-aging moisturizer is formulated around Sodium Ascorbyl Phosphate and Retinol to soften the look of wrinkles and strengthen the skin barrier.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Glycerin
Caprylic/Capric Triglyceride
Dipropylene Glycol
Cetearyl Alcohol
Hydrogenated Polydecene
Methyl Trimethicone
Hydrogenated Poly(C6-14 Olefin)
Butyrospermum Parkii Butter
1,2-Hexanediol
Phenyl Trimethicone
Dicaprylyl Ether
Cetearyl Olivate
Panthenol
Glyceryl Stearate
Behenyl Alcohol
Sorbitan Olivate
Theobroma Cacao Seed Extract
2,3-Butanediol
Cetearyl Glucoside
Ceramide NP
Ceramide Ng
Ceramide Ns
Ceramide As
Ceramide AP
Cholesterol
Pentaerythrityl Distearate
Hydrogenated Lecithin
Palmitic Acid
Stearic Acid
Microcrystalline Cellulose
Glyceryl Stearate Se
Ammonium Acryloyldimethyltaurate/Vp Copolymer
Cellulose Gum
Dextrin
Glyceryl Polymethacrylate
Pelargonium Graveolens Flower Oil
Olea Europaea Fruit Oil
Citrus Aurantium Bergamia Fruit Oil
Salvia Officinalis Oil
Citronellol
Tocopherol
CI 19140
Water, Glycerin, Caprylic/Capric Triglyceride, Dipropylene Glycol, Cetearyl Alcohol, Hydrogenated Polydecene, Methyl Trimethicone, Hydrogenated Poly(C6-14 Olefin), Butyrospermum Parkii Butter, 1,2-Hexanediol, Phenyl Trimethicone, Dicaprylyl Ether, Cetearyl Olivate, Panthenol, Glyceryl Stearate, Behenyl Alcohol, Sorbitan Olivate, Theobroma Cacao Seed Extract, 2,3-Butanediol, Cetearyl Glucoside, Ceramide NP, Ceramide Ng, Ceramide Ns, Ceramide As, Ceramide AP, Cholesterol, Pentaerythrityl Distearate, Hydrogenated Lecithin, Palmitic Acid, Stearic Acid, Microcrystalline Cellulose, Glyceryl Stearate Se, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Cellulose Gum, Dextrin, Glyceryl Polymethacrylate, Pelargonium Graveolens Flower Oil, Olea Europaea Fruit Oil, Citrus Aurantium Bergamia Fruit Oil, Salvia Officinalis Oil, Citronellol, Tocopherol, CI 19140
Sodium Ascorbyl Phosphate
Cetyl Alcohol
Neopentyl Glycol Diheptanoate
Potassium Cetyl Phosphate
PEG-100 Stearate
PEG-12 Glyceryl Dimyristate
Bis-Diglyceryl Polyacyladipate-2
Dimethicone
Glyceryl Ascorbate
Tetrahexyldecyl Ascorbate
Retinol
Ceramide EOP
Ceramide Eos
Caprooyl Phytosphingosine
Caprooyl Sphingosine
Squalane
Punica Granatum Extract
Pongamia Glabra Seed Oil
Glycyrrhiza Glabra Root
Vitis Vinifera
Tocopheryl Acetate
Carnosine
Sodium PCA
Butylene Glycol
Sodium Citrate
Ceteareth-25
Polysorbate 20
Ethylhexyl Stearate
Sodium Hydroxide
Trideceth-6
Propyl Gallate
Sodium Polyacrylate
Behenic Acid
Disodium EDTA
Phenoxyethanol
Caprylyl Glycol
Chlorphenesin
Water, Sodium Ascorbyl Phosphate, Cetyl Alcohol, Neopentyl Glycol Diheptanoate, Potassium Cetyl Phosphate, Glyceryl Stearate, PEG-100 Stearate, Glycerin, PEG-12 Glyceryl Dimyristate, Bis-Diglyceryl Polyacyladipate-2, Dimethicone, Glyceryl Ascorbate, Tetrahexyldecyl Ascorbate, Retinol, Ceramide NP, Ceramide Ns, Ceramide AP, Ceramide EOP, Ceramide Eos, Cholesterol, Caprooyl Phytosphingosine, Caprooyl Sphingosine, Squalane, Punica Granatum Extract, Pongamia Glabra Seed Oil, Glycyrrhiza Glabra Root, Vitis Vinifera, Tocopheryl Acetate, Carnosine, Panthenol, Sodium PCA, Butylene Glycol, Sodium Citrate, Ceteareth-25, Polysorbate 20, Ethylhexyl Stearate, Sodium Hydroxide, Trideceth-6, Propyl Gallate, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Sodium Polyacrylate, Behenic Acid, Disodium EDTA, Phenoxyethanol, Caprylyl Glycol, Chlorphenesin
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Ammonium Acryloyldimethyltaurate/Vp Copolymer is a synthetically created polymer. It's used as a film-forming agent and used to thicken the consistency of products.
Think of it as a supportive ingredient that helps your gel-creams feel silky, "cloud cream-like", and spread evenly without being greasy.
The Cosmetic Ingredient Review (CIR) Expert Panel evaluated it (along with 22 other acryloyldimethyltaurate polymers) and concluded it's:
Due to its large molecular size, it sits on the surface of skin rather than penetrating it.
Ceramide AP is is a skin-identical lipid that mimics what your skin already makes naturally. Ceramides help maintain epidermal integrity and barrier function.
You'll often see this ingredient paired with other ceramides (like ceramide NP), cholesterol, or fatty acids because this combination best mimics the natural lipid mix your skin already has.
The skin's ability to produce ceramides gets disrupted in skin conditions like eczema. This in turn weakens the skin barrier and applying ceramides topically has been shown to replenish what's been lost to restore barrier function.
Most of the studies with Ceramide AP test it as part of a multi-ceramide complex; studies reinforce ceramide AP's role in rebalancing ceramides in skin and improving skin hydration.
Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.
Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.
This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.
A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.
Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.
Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.
Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.
Ceramide NS is formally known as Ceramide 2. It is one of the major ceramides in the stratum corneum (outermost layer of skin) plays a role in forming a protective barrier.
Due to its structure, skin lipids can be packed tightly and in turn, this strengthens the barrier and reduces water loss.
Studies show conditions like atopic dermatitis can worsen when ceramide NS levels are low.
Cholesterol is a lipid that is naturally found in human skin and is one of the three key components of your skin barrier. In skincare, it is an emollient and barrier-repairing ingredient.
It works by fitting directly into the lipid layers of skin to help restore structure and reduce transepidermal water loss (TEWL).
This is a great ingredient for dry, compromised, or aging skin; our skin starts to produce less cholesterol with age.
Research shows cholesterol works best in combination with ceramides and fatty acids, the other two major components in your skin barrier.
Cholesterol is also a well-establish penetration enhancer and can help other actives absorb more effectively.
Cosmetic-grade cholesterol is usually derived from lanolin but plant and synthetic options also exist. We recommend reaching out to the brand if you have questions about their source of cholesterol.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Glyceryl Stearate is made by reacting glycerin with stearic acid (typically sourced from plant oils like palm or coconut). It's an emulsifier, emollient, and mild occlusive.
Emulsifiers help ingredients like oil and water stay mixed so your formula stays nicely blended and uniform in texture.
This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototoxic, and non-photoallergenic.
A close cousin of this ingredient is Glyceryl Stearate SE ("self-emulsifying"). This just has a small amount of sodium or potassium stearate added so it can emulsify without a co-emulsifier.
Since this ingredient is an ester of a C18 fatty acid, it may not be fungal acne safe. The Malassezia yeast can potentially metabolize within the C11-C24 range.
Fun fact: The human body also creates Glyceryl Stearate naturally.
Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!