Dr. Lara Devgan Peptide Eye Cream Versus Algenist Complete Eye Renewal Balm

Dr. Lara Devgan Peptide Eye Cream Versus Algenist Complete Eye Renewal Balm

This anti-aging eye moisturizer is formulated around Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7 to soften the look of wrinkles and hydrate skin.

This anti-aging eye moisturizer is formulated around Caffeine and Palmitoyl Tetrapeptide-7 to soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Helianthus Annuus Seed Oil

Glycerin

Dimethicone

Isopropyl Palmitate

Palmitoyl Tripeptide-1

Palmitoyl Tetrapeptide-7

Steareth-20

Chrysin

N-Hydroxysuccinimide

Butylene Glycol

Carbomer

Polysorbate 20

Glycol Distearate

Glyceryl Stearate

PEG-100 Stearate

Stearic Acid

Stearyl Alcohol

Phytonadione Epoxide

Vitis Vinifera Seed Oil

Persea Gratissima Oil

Tocopheryl Acetate

Allantoin

Titanium Dioxide

Tetrasodium EDTA

Triethanolamine

Phenoxyethanol

Ethylhexylglycerin

Water, Helianthus Annuus Seed Oil, Glycerin, Dimethicone, Isopropyl Palmitate, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Steareth-20, Chrysin, N-Hydroxysuccinimide, Butylene Glycol, Carbomer, Polysorbate 20, Glycol Distearate, Glyceryl Stearate, PEG-100 Stearate, Stearic Acid, Stearyl Alcohol, Phytonadione Epoxide, Vitis Vinifera Seed Oil, Persea Gratissima Oil, Tocopheryl Acetate, Allantoin, Titanium Dioxide, Tetrasodium EDTA, Triethanolamine, Phenoxyethanol, Ethylhexylglycerin

Isopropyl Isostearate

Palmitic Acid

Pentylene Glycol

Glyceryl Stearate Se

Dimethicone Crosspolymer

Butyrospermum Parkii Butter

Cetearyl Alcohol

Undaria Pinnatifida Extract

Limnanthes Alba Seed Oil

Parachlorella Beijerinckii Exopolysaccharides

Alaria Esculenta Extract

Bambusa Vulgaris Leaf/Stem Extract

Aloe Barbadensis Leaf Juice

Aloe Barbadensis Leaf Juice Powder

Camellia Sinensis Leaf Extract

Cucumis Sativus Fruit Extract

Caffeine

Tetrapeptide-21

Dipeptide-2

Magnesium Ascorbyl Phosphate

Malus Domestica Fruit Cell Culture Extract

Rubus Idaeus Leaf Extract

Glucosamine Hcl

Pisum Sativum Extract

Inula Crithmoide Extract

Phospholipids

Biotin

Hesperidin Methyl Chalcone

Lecithin

Caprylic/Capric Triglyceride

Leuconostoc/Radish Root Ferment Filtrate

Vinyl Dimethicone/Methicone Silsesquioxane Crosspolymer

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Ceteareth-20

Xanthan Gum

Sodium Citrate

Citric Acid

Disodium EDTA

Aminomethyl Propanol

Potassium Sorbate

Chlorhexidine Digluconate

Caprylyl Glycol

Hexylene Glycol

Sodium Benzoate

Water, Isopropyl Isostearate, Glycerin, Dimethicone, Palmitic Acid, Pentylene Glycol, Glyceryl Stearate Se, Stearic Acid, Dimethicone Crosspolymer, Butyrospermum Parkii Butter, Cetearyl Alcohol, Undaria Pinnatifida Extract, Limnanthes Alba Seed Oil, Parachlorella Beijerinckii Exopolysaccharides, Alaria Esculenta Extract, Bambusa Vulgaris Leaf/Stem Extract, Aloe Barbadensis Leaf Juice, Aloe Barbadensis Leaf Juice Powder, Camellia Sinensis Leaf Extract, Cucumis Sativus Fruit Extract, Tocopheryl Acetate, Caffeine, Tetrapeptide-21, Dipeptide-2, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Magnesium Ascorbyl Phosphate, Malus Domestica Fruit Cell Culture Extract, Rubus Idaeus Leaf Extract, Glucosamine Hcl, Pisum Sativum Extract, Inula Crithmoide Extract, Phospholipids, Biotin, N-Hydroxysuccinimide, Chrysin, Hesperidin Methyl Chalcone, Lecithin, Caprylic/Capric Triglyceride, Leuconostoc/Radish Root Ferment Filtrate, Vinyl Dimethicone/Methicone Silsesquioxane Crosspolymer, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Steareth-20, Ceteareth-20, Butylene Glycol, Xanthan Gum, Sodium Citrate, Citric Acid, Disodium EDTA, Aminomethyl Propanol, Potassium Sorbate, Chlorhexidine Digluconate, Caprylyl Glycol, Hexylene Glycol, Ethylhexylglycerin, Sodium Benzoate, Phenoxyethanol

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

We don't have a description for Chrysin yet.

Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.

What it does:

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

We don't have a description for N-Hydroxysuccinimide yet.

Palmitoyl Tetrapeptide-7 (formerly Palmitoyl Tetrapeptide-3) is a synthetic peptide. Its main job is to fight what researchers call "inflammaging".

"Inflammaging" is the slow, low-grade chronic inflammation that quietly breaks down collagen as we age.

This ingredient calms down a specific inflammation signal in your skin cells (called IL-6). When left unchecked, this signal triggers enzymes that break down collagen and elastin.

Clinical testing showed statistically significant improvements in:

Studies also found the more of this ingredient used, the more your skin produces Collagen I, fibronectin, and hyaluronic acid.

You'll likely see this ingredient paired with Palmitoyl Tripeptide-1 in the well-known Matrixyl 3000 complex for enhanced anti-aging effects.

A 3% concentration applied twice daily for two months showed meaningful skin rejuvenation results in clinical panels.

Fungal acne note: Usually a palmitic acid component can feed Malassezia in unbound form, but here is is covalently bonded to the peptide. This means it is very difficult for Malassezia to access, and therefore very unlikely to cause fungal acne.

Palmitoyl Tripeptide-1 (aka Pal-GHK) is a synthetic signal peptide made of three amino acids attached to palmitic acid.

That fatty acid attachment is the key: it boosts the peptide's ability to penetrate the skin barrier. This puts it closer to the dermal cells where it can actually make a difference.

Once there, it acts as a matrikine, a signaling peptide that prompts fibroblasts to produce more collagen, fibronectin, and hyaluronic acid.

In vitro studies show it can boost collagen production in skin cells even when UV-damaged skin samples were treated with it at a tiny concentration (it almost fully restored dermal collagen at 5ppm). It achieved this at 100x lower concentration than retinoic acid, which needed 500 ppm to do the same thing.

Human clinical data is promising, but modest:

A study of 23 female volunteers found a small but statistically significant increase (~4%) in skin thickness after treatment at 4 ppm.

A separate small trial of 15 women showed statistically significant reductions in wrinkle length, depth, and skin roughness after applying it twice daily for four weeks.

You'll likely see Pal-GHK paired with Palmitoyl Tetrapeptide-7 as part of the Matrixyl 3000 complex.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Steareth-20 is an emulsifier and solubilizer. It is created from stearyl alcohol with ~20 units of ethylene oxide to give it a strong preference for water.

As an emulsifier, it helps oil-in-water emulsions like lotions, creams, and cleansers stay stable. It also solubilizes small amounts of oil-loving ingredients (like fragrance) into water-based formulas.

You'll likely find this ingredient with steareth-2 (it's oil-loving sister) where the two work together to give products a cushiony feel.

Typical use levels sit at around 1-5% and this ingredient has been found to be non-irritating by the CIR Expert Panel.

Stearic Acid is a fatty acid that is already found in your skin. It's one of the free fatty acids that works alongside ceramides and cholesterols to maintain your barrier.

In cosmetics, it is a multitasker:

Safety-wise, the CIR Expert Panel has concluded it to be safe in cosmetics when formulated to be non-irritating and non-sensitizing.

Free stearic acid is a C18 fatty acid that the Malassezia yeast can substrate, so this ingredient may not be fungal acne safe.

Tocopheryl Acetate is a stable, shelf-friendly form of vitamin E.

Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.

It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.

One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.

Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.

Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.

The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.

Most leave-on skincare keeps it at the lower end, often between 0.5-1%.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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