Skin science article
Drunk Elephant A-Passioni Retinol Cream Versus First Aid Beauty Ultra Repair Cream Intense Hydration
Drunk Elephant A-Passioni Retinol Cream Versus First Aid Beauty Ultra Repair Cream Intense Hydration This anti-aging treatment is formulated around Retinol and Niacinamide to soften the look of wrinkles and refine skin texture. This calming moisturizer is form
Drunk Elephant A-Passioni Retinol Cream Versus First Aid Beauty Ultra Repair Cream Intense Hydration
This anti-aging treatment is formulated around Retinol and Niacinamide to soften the look of wrinkles and refine skin texture.
This calming moisturizer is formulated around Colloidal Oatmeal and Squalane to calm redness and hydrate skin.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Glycerin
Coco-Caprylate
Stearic Acid
Coconut Alkanes
Glyceryl Stearate
Niacinamide
Caprylic/Capric Triglyceride
Cetearyl Alcohol
Pentylene Glycol
Passiflora Edulis Seed Oil
Retinol
Simmondsia Chinensis Seed Oil
Sclerocarya Birrea Seed Oil
Prunus Armeniaca Kernel Oil
Cetyl Ethylhexanoate
Palmitoyl Tripeptide-1
Palmitoyl Tetrapeptide-7
Brassica Oleracea Acephala Leaf Extract
Brassica Oleracea Italica Extract
Tetrahexyldecyl Ascorbate
Chrysin
Persea Gratissima Oil
Linoleic Acid
Linolenic Acid
Ceramide NP
Xanthophylls
Phytosphingosine
Phytosterols
Jojoba Esters
Physalis Pubescens Fruit Juice
Stearyl Glycyrrhetinate
Oryza Sativa Extract
Glycine Soja Oil
Carthamus Tinctorius Seed Oil
Palmitoyl Hexapeptide-12
Cetyl Palmitate
Trehalose
Lauric Acid
Sodium Hyaluronate Crosspolymer
Olea Europaea Fruit Oil
Glucosamine Hcl
Tocopheryl Acetate
Coco-Caprylate/Caprate
Pisum Sativum Extract
Tocopherol
Bambusa Vulgaris Leaf/Stem Extract
Phenoxyethanol
Caprylyl Glycol
Carbomer
Trideceth-6 Phosphate
N-Hydroxysuccinimide
Ceteareth-20
Sodium Hydroxide
Laureth-23
Steareth-20
Propanediol
Chlorhexidine Digluconate
Polysorbate 20
Trisodium Ethylenediamine Disuccinate
Chlorphenesin
Potassium Sorbate
Ethylhexylglycerin
Water, Glycerin, Coco-Caprylate, Stearic Acid, Coconut Alkanes, Glyceryl Stearate, Niacinamide, Caprylic/Capric Triglyceride, Cetearyl Alcohol, Pentylene Glycol, Passiflora Edulis Seed Oil, Retinol, Simmondsia Chinensis Seed Oil, Sclerocarya Birrea Seed Oil, Prunus Armeniaca Kernel Oil, Cetyl Ethylhexanoate, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Brassica Oleracea Acephala Leaf Extract, Brassica Oleracea Italica Extract, Tetrahexyldecyl Ascorbate, Chrysin, Persea Gratissima Oil, Linoleic Acid, Linolenic Acid, Ceramide NP, Xanthophylls, Phytosphingosine, Phytosterols, Jojoba Esters, Physalis Pubescens Fruit Juice, Stearyl Glycyrrhetinate, Oryza Sativa Extract, Glycine Soja Oil, Carthamus Tinctorius Seed Oil, Palmitoyl Hexapeptide-12, Cetyl Palmitate, Trehalose, Lauric Acid, Sodium Hyaluronate Crosspolymer, Olea Europaea Fruit Oil, Glucosamine Hcl, Tocopheryl Acetate, Coco-Caprylate/Caprate, Pisum Sativum Extract, Tocopherol, Bambusa Vulgaris Leaf/Stem Extract, Phenoxyethanol, Caprylyl Glycol, Carbomer, Trideceth-6 Phosphate, N-Hydroxysuccinimide, Ceteareth-20, Sodium Hydroxide, Laureth-23, Steareth-20, Propanediol, Chlorhexidine Digluconate, Polysorbate 20, Trisodium Ethylenediamine Disuccinate, Chlorphenesin, Potassium Sorbate, Ethylhexylglycerin
Colloidal Oatmeal 0.5%
C12-15 Alkyl Benzoate
Glyceryl Stearate Se
Dimethicone
Squalane
Butyrospermum Parkii Butter
Xanthan Gum
Allantoin
Tetrasodium EDTA
Chrysanthemum Parthenium Extract
Camellia Sinensis Leaf Extract
Glycyrrhiza Glabra Root Extract
Eucalyptus Globulus Leaf Oil
Colloidal Oatmeal 0.5%, Water, Stearic Acid, Glycerin, C12-15 Alkyl Benzoate, Caprylic/Capric Triglyceride, Glyceryl Stearate Se, Glyceryl Stearate, Cetearyl Alcohol, Dimethicone, Squalane, Butyrospermum Parkii Butter, Phenoxyethanol, Caprylyl Glycol, Xanthan Gum, Allantoin, Sodium Hydroxide, Tetrasodium EDTA, Chrysanthemum Parthenium Extract, Camellia Sinensis Leaf Extract, Glycyrrhiza Glabra Root Extract, Ceramide NP, Eucalyptus Globulus Leaf Oil
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.
Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.
In practice, that translates to a long shelf life and a consistently elegant skin feel.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.
Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.
This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.
This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.
Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.
This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.
A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.
Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.
Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.
Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.
Cetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier.
Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient.
It plays several roles in a formula:
Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products.
Multiple assessments have found it to be non-irritating and non-sensitizing to most people.
However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers.
Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy.
Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans.
Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients.
This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain lengths that fall within the range that Malassezia can metabolize.
A 2019 study has also observed Malassezia growth in the presence of this ingredient, confirming it to be not-fungal acne safe.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Glyceryl Stearate is made by reacting glycerin with stearic acid (typically sourced from plant oils like palm or coconut). It's an emulsifier, emollient, and mild occlusive.
Emulsifiers help ingredients like oil and water stay mixed so your formula stays nicely blended and uniform in texture.
This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototoxic, and non-photoallergenic.
A close cousin of this ingredient is Glyceryl Stearate SE ("self-emulsifying"). This just has a small amount of sodium or potassium stearate added so it can emulsify without a co-emulsifier.
Since this ingredient is an ester of a C18 fatty acid, it may not be fungal acne safe. The Malassezia yeast can potentially metabolize within the C11-C24 range.
Fun fact: The human body also creates Glyceryl Stearate naturally.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Stearic Acid is a fatty acid that is already found in your skin. It's one of the free fatty acids that works alongside ceramides and cholesterols to maintain your barrier.
In cosmetics, it is a multitasker:
Safety-wise, the CIR Expert Panel has concluded it to be safe in cosmetics when formulated to be non-irritating and non-sensitizing.
Free stearic acid is a C18 fatty acid that the Malassezia yeast can substrate, so this ingredient may not be fungal acne safe.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!