Skin science article
Drunk Elephant Lala Retro Whipped Cream Versus SkinCeuticals Triple Lipid Restore 2:4:2
Drunk Elephant Lala Retro Whipped Cream Versus SkinCeuticals Triple Lipid Restore 2:4:2 This barrier-repair moisturizer is formulated around Camellia Sinensis Seed Oil and Ceramide NP to strengthen the skin barrier and hydrate skin. This barrier-repair moistur
Drunk Elephant Lala Retro Whipped Cream Versus SkinCeuticals Triple Lipid Restore 2:4:2
This barrier-repair moisturizer is formulated around Camellia Sinensis Seed Oil and Ceramide NP to strengthen the skin barrier and hydrate skin.
This barrier-repair moisturizer is formulated around Cholesterol and Ceramide NP to strengthen the skin barrier and soften the look of wrinkles.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Glycerin
Caprylic/Capric Triglyceride
Isopropyl Isostearate
Camellia Sinensis Seed Oil
Glyceryl Stearate Se
Cetearyl Alcohol
Palmitic Acid
Stearic Acid
Pentylene Glycol
Plantago Lanceolata Leaf Extract
Adansonia Digitata Seed Oil
Citrullus Lanatus Seed Oil
Passiflora Edulis Seed Oil
Schinziophyton Rautanenii Kernel Oil
Sclerocarya Birrea Seed Oil
Polyglyceryl-6 Ximenia Americana Seedate
Cholesterol
Ceramide AP
Ceramide EOP
Sodium Hyaluronate Crosspolymer
Ceramide NP
Phytosphingosine
Ceteareth-20
Trisodium Ethylenediamine Disuccinate
Tocopherol
Sodium Lauroyl Lactylate
Sodium Hydroxide
Citric Acid
Carbomer
Xanthan Gum
Caprylyl Glycol
Chlorphenesin
Phenoxyethanol
Ethylhexylglycerin
Water, Glycerin, Caprylic/Capric Triglyceride, Isopropyl Isostearate, Camellia Sinensis Seed Oil, Glyceryl Stearate Se, Cetearyl Alcohol, Palmitic Acid, Stearic Acid, Pentylene Glycol, Plantago Lanceolata Leaf Extract, Adansonia Digitata Seed Oil, Citrullus Lanatus Seed Oil, Passiflora Edulis Seed Oil, Schinziophyton Rautanenii Kernel Oil, Sclerocarya Birrea Seed Oil, Polyglyceryl-6 Ximenia Americana Seedate, Cholesterol, Ceramide AP, Ceramide EOP, Sodium Hyaluronate Crosspolymer, Ceramide NP, Phytosphingosine, Ceteareth-20, Trisodium Ethylenediamine Disuccinate, Tocopherol, Sodium Lauroyl Lactylate, Sodium Hydroxide, Citric Acid, Carbomer, Xanthan Gum, Caprylyl Glycol, Chlorphenesin, Phenoxyethanol, Ethylhexylglycerin
Dimethicone
Hydrogenated Polyisobutene
C12-15 Alkyl Benzoate
Helianthus Annuus Seed Oil Unsaponifiables
Bis-PEG-18 Methyl Ether Dimethyl Silane
Sodium Polyacrylate
PEG-10 Dimethicone
Nylon-12
Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone
Dimethicone/PEG-10/15 Crosspolymer
Disteardimonium Hectorite
Hydroxyethylpiperazine Ethane Sulfonic Acid
Ammonium Polyacryloyldimethyl Taurate
PEG/PPG-18/18 Dimethicone
Propylene Carbonate
Disodium EDTA
Acrylonitrile/Methyl Methacrylate/Vinylidene Chloride Copolymer
Adenosine
Dipropylene Glycol
Lavandula Angustifolia Oil
Rosmarinus Officinalis Leaf Oil
T-Butyl Alcohol
Mentha Piperita Oil
Sodium Citrate
Linalool
Isobutane
BHT
Limonene
Water, Dimethicone, Hydrogenated Polyisobutene, Glycerin, Cholesterol, C12-15 Alkyl Benzoate, Ceramide NP, Helianthus Annuus Seed Oil Unsaponifiables, Bis-PEG-18 Methyl Ether Dimethyl Silane, Sodium Polyacrylate, PEG-10 Dimethicone, Nylon-12, Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone, Dimethicone/PEG-10/15 Crosspolymer, Phenoxyethanol, Disteardimonium Hectorite, Hydroxyethylpiperazine Ethane Sulfonic Acid, Ammonium Polyacryloyldimethyl Taurate, Chlorphenesin, Caprylyl Glycol, PEG/PPG-18/18 Dimethicone, Propylene Carbonate, Disodium EDTA, Acrylonitrile/Methyl Methacrylate/Vinylidene Chloride Copolymer, Adenosine, Dipropylene Glycol, Lavandula Angustifolia Oil, Rosmarinus Officinalis Leaf Oil, T-Butyl Alcohol, Mentha Piperita Oil, Sodium Citrate, Linalool, Isobutane, Ceramide EOP, BHT, Tocopherol, Limonene
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Ceramide EOP is formally known as Ceramide 1.
It is naturally found in skin and part of the intercellular "mortar" holding everything together in your outermost layer.
EOP stands for a linked Ester fatty acid, a linked Omega hydroxy fatty acid, and the Phytosphingosine base.
What makes Ceramide EOP special is its ultra-long fatty acid chain; this unique structure allows it to bridge the lipid layers in your skin barrier to prevent water loss (something no other ceramide can do).
Low levels of Ceramide EOP have been found in people with eczema and psoriasis.
Using it together with other ceramides, cholesterol, and linoleic acid have been shown to meaningfully improve hydration and reduce water loss.
In one clinical study, a regimen using Ceramide EOP, NP, and AP led to significant symptom improvements in patients with eczema, psoriasis, and dry skin in just 4 weeks.
You'll usually see concentrations between 0.1-0.5% in formulations. Overall, this is a well-tolerated and safe ingredient for cosmetic use.
Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.
Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.
This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.
A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.
Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.
Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.
Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.
Chlorphenesin is a synthetic preservative. It helps protect a product against bacteria in order to extend shelf life. In most cases, Chlorphenesin is paired with other preservatives such as phenoxyethanol and caprylyl glycol.
Chlorphenesin is a biocide. This means it is able to help fight the microorganisms on our skin. It is also able to fight odor-releasing bacteria.
Chlorphenesin is soluble in both water and glycerin.
Studies show Chlorphenesin is easily absorbed by our skin. You should speak with a skincare professional if you have concerns about using Chlorphenesin.
Cholesterol is a lipid that is naturally found in human skin and is one of the three key components of your skin barrier. In skincare, it is an emollient and barrier-repairing ingredient.
It works by fitting directly into the lipid layers of skin to help restore structure and reduce transepidermal water loss (TEWL).
This is a great ingredient for dry, compromised, or aging skin; our skin starts to produce less cholesterol with age.
Research shows cholesterol works best in combination with ceramides and fatty acids, the other two major components in your skin barrier.
Cholesterol is also a well-establish penetration enhancer and can help other actives absorb more effectively.
Cosmetic-grade cholesterol is usually derived from lanolin but plant and synthetic options also exist. We recommend reaching out to the brand if you have questions about their source of cholesterol.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Tocopherol is a fat-soluble antioxidant known as Vitamin E.
You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.
Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.
It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.
This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.
Concentrations usually range from 0.1-1% in most leave-on products.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!