Skin science article
Drunk Elephant Protini Polypeptide Cream Versus Dermalogica Active Moist
Drunk Elephant Protini Polypeptide Cream Versus Dermalogica Active Moist This anti-aging moisturizer is formulated around Sclerocarya Birrea Seed Oil and Sh-Oligopeptide-1 to soften the look of wrinkles and hydrate skin. This barrier-repair moisturizer is form
Drunk Elephant Protini Polypeptide Cream Versus Dermalogica Active Moist
This anti-aging moisturizer is formulated around Sclerocarya Birrea Seed Oil and Sh-Oligopeptide-1 to soften the look of wrinkles and hydrate skin.
This barrier-repair moisturizer is formulated around Caprylic/Capric Triglyceride and Saccharide Isomerate to strengthen the skin barrier and hydrate skin.
What's inside
Key Ingredients
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Benefits
Concerns
Ingredients Side-by-side
Water
Dicaprylyl Carbonate
Glycerin
Cetearyl Alcohol
Cetearyl Olivate
Sorbitan Olivate
Sclerocarya Birrea Seed Oil
Bacillus/Folic Acid Ferment Filtrate Extract
Nymphaea Alba Root Extract
Sh-Oligopeptide-1
Sh-Oligopeptide-2
Sh-Polypeptide-1
Sh-Polypeptide-9
Sh-Polypeptide-11
Copper Palmitoyl Heptapeptide-14
Heptapeptide-15 Palmitate
Palmitoyl Tetrapeptide-7
Palmitoyl Tripeptide-1
Alanine
Arginine
Glycine
Histidine
Isoleucine
Phenylalanine
Proline
Serine
Threonine
Valine
Acetyl Glutamine
Coconut Alkanes
Coco-Caprylate/Caprate
Sodium Hyaluronate
Aspartic Acid
Linoleic Acid
Linolenic Acid
Lecithin
Butylene Glycol
Polyvinyl Alcohol
Sodium Lactate
Sodium PCA
PCA
Sorbitan Isostearate
Carbomer
Polysorbate 20
Polysorbate 60
Lactic Acid/Glycolic Acid Copolymer
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Xanthan Gum
Isomalt
1,2-Hexanediol
Caprylyl Glycol
Chlorphenesin
Phenoxyethanol
Tocopherol
Sodium Benzoate
Phenylpropanol
Glyceryl Caprylate
Symphytum Officinale Callus Culture Extract
Water, Dicaprylyl Carbonate, Glycerin, Cetearyl Alcohol, Cetearyl Olivate, Sorbitan Olivate, Sclerocarya Birrea Seed Oil, Bacillus/Folic Acid Ferment Filtrate Extract, Nymphaea Alba Root Extract, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-9, Sh-Polypeptide-11, Copper Palmitoyl Heptapeptide-14, Heptapeptide-15 Palmitate, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Alanine, Arginine, Glycine, Histidine, Isoleucine, Phenylalanine, Proline, Serine, Threonine, Valine, Acetyl Glutamine, Coconut Alkanes, Coco-Caprylate/Caprate, Sodium Hyaluronate, Aspartic Acid, Linoleic Acid, Linolenic Acid, Lecithin, Butylene Glycol, Polyvinyl Alcohol, Sodium Lactate, Sodium PCA, PCA, Sorbitan Isostearate, Carbomer, Polysorbate 20, Polysorbate 60, Lactic Acid/Glycolic Acid Copolymer, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Xanthan Gum, Isomalt, 1,2-Hexanediol, Caprylyl Glycol, Chlorphenesin, Phenoxyethanol, Tocopherol, Sodium Benzoate, Phenylpropanol, Glyceryl Caprylate, Symphytum Officinale Callus Culture Extract
Caprylic/Capric Triglyceride
Pentylene Glycol
Methyl Gluceth-20
Palmitic Acid
Stearic Acid
Saccharide Isomerate
Dimethicone
Glyceryl Stearate
Hydrolyzed Jojoba Esters
Leuconostoc/Radish Root Ferment Filtrate
Arctium Lappa Root Extract
Citrus Limon Fruit Extract
Cucumis Sativus Fruit Extract
Hedera Helix Extract
Malva Sylvestris Flower Extract
Nasturtium Officinale Extract
Propanediol
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Allantoin
Tetrasodium Glutamate Diacetate
Polyquaternium-10
Ethylhexylglycerin
Triethyl Citrate
Myristic Acid
Citrus Aurantium Bergamia Fruit Extract
Citrus Limon Peel Extract
Lavandula Angustifolia Flower/Leaf/Stem Extract
Lavandula Hybrida Flower Extract
Citric Acid
Sodium Citrate
Sodium Hydroxide
Aminomethyl Propanol
Citral
Linalool
Limonene
Water, Caprylic/Capric Triglyceride, Pentylene Glycol, Butylene Glycol, Methyl Gluceth-20, Coconut Alkanes, Cetearyl Alcohol, Palmitic Acid, Stearic Acid, Saccharide Isomerate, Dimethicone, Glyceryl Stearate, Hydrolyzed Jojoba Esters, Leuconostoc/Radish Root Ferment Filtrate, Arctium Lappa Root Extract, Citrus Limon Fruit Extract, Cucumis Sativus Fruit Extract, Hedera Helix Extract, Malva Sylvestris Flower Extract, Nasturtium Officinale Extract, Propanediol, Polysorbate 60, Caprylyl Glycol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Allantoin, Tetrasodium Glutamate Diacetate, Coco-Caprylate/Caprate, Polyquaternium-10, Ethylhexylglycerin, Triethyl Citrate, Myristic Acid, Citrus Aurantium Bergamia Fruit Extract, Citrus Limon Peel Extract, Lavandula Angustifolia Flower/Leaf/Stem Extract, Lavandula Hybrida Flower Extract, Citric Acid, Sodium Citrate, Sodium Hydroxide, Aminomethyl Propanol, Citral, Linalool, Limonene
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Cetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier.
Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient.
It plays several roles in a formula:
Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products.
Multiple assessments have found it to be non-irritating and non-sensitizing to most people.
However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers.
Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy.
Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans.
Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients.
This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain lengths that fall within the range that Malassezia can metabolize.
A 2019 study has also observed Malassezia growth in the presence of this ingredient, confirming it to be not-fungal acne safe.
Coco-Caprylate/Caprate is a lightweight ester created from coconut oil fatty acids, caprylic acid, and capric acid.
It is an emollient that helps soften skin and reduce transepidermal water loss (TEWL). What sets it apart from heavier emollients is its ultralight, non-greasy feel.
Once applied, this ingredient dries down quickly and leaves a dry, silky finish behind. This also helps improve spreadability and texture.
This ingredient has an excellent safety-record and is non-irritating.
Typical concentrations for cosmetics range from 0.5-62%.
Research on Malassezia growth found no growth on fatty acid esters with chain lengths shorter than 12 carbons (it prefers C11-24).
Since Coco-Caprylate/Caprate is built on C8 and C10 fatty acids, it is out of the range that Malassezia metabolizes, and therefore safe for fungal acne.
Coconut Alkanes is a lightweight, plant-derived emollient and solvent made from the fatty acids of coconut oil.
It spreads easily and adds a soft, silky, non-greasy slip, then evaporates rather than sinking into skin. Due to this behavior, it's prized as a natural and renewable replacement for silicones.
Typical use concentrations can go anywhere up to 20%.
The CIR Expert Panel has reviewed coconut oil and its hydrogenated derivatives and found them to be safe as used in cosmetics. It's a low-irritating and well-tolerated ingredient with no notable sensitization concerns.
Because it's a pure saturated hydrocarbon and not a free fatty acid or ester in the C11-24 range that Malassezia can feed on, it doesn't provide the lipids for Malassezia to feed on. This ingredient is generally regarded as safe for fungal acne.
Polysorbate 60 is used to help stabilize products. It is a surfactant and emulsifier. These properties help keep ingredients together in a product. Surfactants help reduce surface tension between ingredients with different states, such as liquids and solids. Emulsifiers help prevent oils and waters from separating.
Polysorbate 60 is sorbitol-based and created from the ethoxylation of sorbitan. Ethoxylation is a chemical reaction used to add ethylene oxide. Sorbitan is a the dehydrated version of sorbitol, a sugar found in fruits.
In this case, the 60 comes from reacting 60 units of ethylene oxide with sorbitan.
Polysorbates are commonly used in medicine and foods.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!