Skin science article
Environ Skin Care Vita Peptide C-Quence Serum 1 Versus ZO Skin Health Daily Power Defense
Environ Skin Care Vita Peptide C-Quence Serum 1 Versus ZO Skin Health Daily Power Defense This anti-aging serum is formulated around Ascorbyl Tetraisopalmitate and Palmitoyl Oligopeptide to soften the look of wrinkles. This barrier-repair moisturizer is formul
Environ Skin Care Vita Peptide C-Quence Serum 1 Versus ZO Skin Health Daily Power Defense
This anti-aging serum is formulated around Ascorbyl Tetraisopalmitate and Palmitoyl Oligopeptide to soften the look of wrinkles.
This barrier-repair moisturizer is formulated around Laminaria Digitata Extract and Beta-Glucan to strengthen the skin barrier and hydrate skin.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Butylene Glycol
PEG-40 Hydrogenated Castor Oil
Glycerin
Ethylhexyl Methoxycinnamate
Sorbitol
Tocopheryl Acetate
C12-15 Alkyl Benzoate
Ascorbyl Tetraisopalmitate
Sodium Lactate
Hydrolyzed Jojoba Esters
Polysorbate 20
Palmitoyl Oligopeptide
Palmitoyl Tetrapeptide-7
Tribehenin
Ceramide Ng
PEG-10 Phytosterol
Palmitoyl Hexapeptide-12
Carbomer
Tea-Lactate
Serine
Lactic Acid
Urea
Allantoin
Retinyl Propionate
Sodium Chloride
Disodium EDTA
Helianthus Annuus Seed Oil
BHT
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Rosmarinus Officinalis Leaf Extract
Epigallocatechin Gallate
Xanthan Gum
Lycopene
Sodium Hydroxide
Sodium Ascorbate
Tocopherol
Glucose
Corn Starch Modified
Zea Mays Starch
Sodium Benzoate
Water, Butylene Glycol, PEG-40 Hydrogenated Castor Oil, Glycerin, Ethylhexyl Methoxycinnamate, Sorbitol, Tocopheryl Acetate, C12-15 Alkyl Benzoate, Ascorbyl Tetraisopalmitate, Sodium Lactate, Hydrolyzed Jojoba Esters, Polysorbate 20, Palmitoyl Oligopeptide, Palmitoyl Tetrapeptide-7, Tribehenin, Ceramide Ng, PEG-10 Phytosterol, Palmitoyl Hexapeptide-12, Carbomer, Tea-Lactate, Serine, Lactic Acid, Urea, Allantoin, Retinyl Propionate, Sodium Chloride, Disodium EDTA, Helianthus Annuus Seed Oil, BHT, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Rosmarinus Officinalis Leaf Extract, Epigallocatechin Gallate, Xanthan Gum, Lycopene, Sodium Hydroxide, Sodium Ascorbate, Tocopherol, Glucose, Corn Starch Modified, Zea Mays Starch, Sodium Benzoate
Dicaprylyl Carbonate
Cetearyl Isononanoate
Pentylene Glycol
Cetearyl Alcohol
Steareth-20
Safflower Oil/Palm Oil Aminopropanediol Esters
Laminaria Digitata Extract
Opuntia Ficus-Indica Stem Extract
Arabidopsis Thaliana Extract
Marrubium Vulgare Meristem Cell Culture
Leontopodium Alpinum Meristem Cell Culture
Retinyl Palmitate
Micrococcus Lysate
Caprylyl Glycol
Hexylene Glycol
Lactose
Galactoarabinan
Lecithin
Schizophyllan
Beta-Glucan
1,2-Hexanediol
Cellulose
Maltodextrin
C14-22 Alcohols
Cetearyl Glucoside
C12-20 Alkyl Glucoside
Hydroxypropyl Methylcellulose
Phenoxyethanol
Ethylhexylglycerin
Parfum
CI 77007
Limonene
Water, Dicaprylyl Carbonate, Cetearyl Isononanoate, Glycerin, Pentylene Glycol, Cetearyl Alcohol, Steareth-20, Safflower Oil/Palm Oil Aminopropanediol Esters, Laminaria Digitata Extract, Opuntia Ficus-Indica Stem Extract, Arabidopsis Thaliana Extract, Marrubium Vulgare Meristem Cell Culture, Leontopodium Alpinum Meristem Cell Culture, Retinyl Palmitate, Tocopheryl Acetate, Tocopherol, Micrococcus Lysate, Caprylyl Glycol, Hexylene Glycol, Lactose, Galactoarabinan, Lecithin, Schizophyllan, Beta-Glucan, 1,2-Hexanediol, Carbomer, Cellulose, Maltodextrin, C14-22 Alcohols, Cetearyl Glucoside, C12-20 Alkyl Glucoside, Hydroxypropyl Methylcellulose, Disodium EDTA, Sodium Hydroxide, Phenoxyethanol, Ethylhexylglycerin, Sodium Benzoate, Parfum, CI 77007, Limonene
Reviews
Be the first to review
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.
Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.
It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.
Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.
A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.
Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
This ingredient mainly works behind the scenes and helps with:
On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).
Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.
Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.
Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.
It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.
Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.
We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.
Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Tocopherol is a fat-soluble antioxidant known as Vitamin E.
You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.
Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.
It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.
This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.
Concentrations usually range from 0.1-1% in most leave-on products.
Tocopheryl Acetate is a stable, shelf-friendly form of vitamin E.
Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.
It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.
One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.
Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.
Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.
Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.
The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.
Most leave-on skincare keeps it at the lower end, often between 0.5-1%.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!