Skin science article
Farmacy Brighten Up 3% TXA Dark Spot Toner with Azelaic Acid + PHA Versus Paula's Choice 1% Retinol Treatment
Farmacy Brighten Up 3% TXA Dark Spot Toner with Azelaic Acid + PHA Versus Paula's Choice 1% Retinol Treatment This brightening toner is formulated around Gluconolactone and Tranexamic Acid to fade the look of dark spots and brighten dull-looking skin. This ant
Farmacy Brighten Up 3% TXA Dark Spot Toner with Azelaic Acid + PHA Versus Paula's Choice 1% Retinol Treatment
This brightening toner is formulated around Gluconolactone and Tranexamic Acid to fade the look of dark spots and brighten dull-looking skin.
This anti-aging treatment is formulated around Retinol and Tetrahexyldecyl Ascorbate to soften the look of wrinkles and refine skin texture.
What's inside
Key Ingredients
Benefits
Concerns
No concerns
Ingredients Side-by-side
Water
Gluconolactone
Pentylene Glycol
Isopentyldiol
Tranexamic Acid
Betaine
Propanediol
Azelaic Acid
Ascorbic Acid
Citrus Aurantium Amara Fruit Extract
Citrus Aurantium Sinensis Peel Extract
Citrus Reticulata Fruit Extract
Glycerin
Allantoin
Polyglycerin-6
Inulin
Fructose
Glucose
Xanthan Gum
Cellulose Gum
Lactic Acid
Citric Acid
Sodium Phytate
Cellulose
Water, Gluconolactone, Pentylene Glycol, Isopentyldiol, Tranexamic Acid, Betaine, Propanediol, Azelaic Acid, Ascorbic Acid, Citrus Aurantium Amara Fruit Extract, Citrus Aurantium Sinensis Peel Extract, Citrus Reticulata Fruit Extract, Glycerin, Allantoin, Polyglycerin-6, Inulin, Fructose, Glucose, Xanthan Gum, Cellulose Gum, Lactic Acid, Citric Acid, Sodium Phytate, Cellulose
Dimethicone
Butylene Glycol
Isononyl Isononanoate
Castor Isostearate Succinate
Glyceryl Stearate
C12-15 Alkyl Benzoate
Dimethicone Crosspolymer
PEG-33
Polysorbate 20
Behenyl Alcohol
PEG-100 Stearate
Pentaerythrityl Tetraisostearate
Polymethylsilsesquioxane
Tetrahexyldecyl Ascorbate
Retinol
Ceramide Ng
Palmitoyl Tetrapeptide-7
Palmitoyl Hexapeptide-12
Sodium Hyaluronate
Dipotassium Glycyrrhizate
Glycyrrhiza Glabra Root Extract
Avena Sativa Kernel Extract
Arctium Lappa Seed Oil
Salix Alba Extract
Glycine Soja Sterols
Lecithin
Tocopheryl Acetate
Hydrolyzed Soy Protein
Sorbitan Laurate
Acetyl Dipeptide-1 Cetyl Ester
Disodium EDTA
Hydroxyethylcellulose
Palmitoyl Tripeptide-1
Sodium Hydroxide
Tribehenin
Caprylyl Glycol
Ethylhexylglycerin
PEG-75 Shea Butter Glycerides
PPG-12/Smdi Copolymer
PEG-10 Phytosterol
PEG-8 Dimethicone
PEG-14
Magnesium Aluminum Silicate
Arachidyl Glucoside
Arachidyl Alcohol
Sclerotium Gum
Carbomer
Phenoxyethanol
Benzoic Acid
Water, Dimethicone, Glycerin, Butylene Glycol, Isononyl Isononanoate, Castor Isostearate Succinate, Glyceryl Stearate, C12-15 Alkyl Benzoate, Dimethicone Crosspolymer, PEG-33, Polysorbate 20, Behenyl Alcohol, PEG-100 Stearate, Pentaerythrityl Tetraisostearate, Polymethylsilsesquioxane, Tetrahexyldecyl Ascorbate, Retinol, Ceramide Ng, Palmitoyl Tetrapeptide-7, Palmitoyl Hexapeptide-12, Sodium Hyaluronate, Dipotassium Glycyrrhizate, Glycyrrhiza Glabra Root Extract, Avena Sativa Kernel Extract, Arctium Lappa Seed Oil, Salix Alba Extract, Glycine Soja Sterols, Lecithin, Allantoin, Tocopheryl Acetate, Hydrolyzed Soy Protein, Sorbitan Laurate, Acetyl Dipeptide-1 Cetyl Ester, Disodium EDTA, Hydroxyethylcellulose, Palmitoyl Tripeptide-1, Sodium Hydroxide, Tribehenin, Caprylyl Glycol, Ethylhexylglycerin, Pentylene Glycol, PEG-75 Shea Butter Glycerides, PPG-12/Smdi Copolymer, PEG-10 Phytosterol, PEG-8 Dimethicone, PEG-14, Magnesium Aluminum Silicate, Arachidyl Glucoside, Arachidyl Alcohol, Sclerotium Gum, Carbomer, Phenoxyethanol, Benzoic Acid
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Allantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.
Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.
Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.
It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.
Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.
This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.
Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.
Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:
Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.
On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.
Typical use levels in a formula run about 1-5%.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!