Skin science article
Filorga Hydra - Hyal Serum Versus The Ordinary "Buffet" + Copper Peptides 1%
Filorga Hydra - Hyal Serum Versus The Ordinary "Buffet" + Copper Peptides 1% This hydrating serum is formulated around Hydrolyzed Sodium Hyaluronate and Sodium Hyaluronate to hydrate skin and soften the look of wrinkles. This anti-aging serum is formulated aro
Filorga Hydra - Hyal Serum Versus The Ordinary "Buffet" + Copper Peptides 1%
This hydrating serum is formulated around Hydrolyzed Sodium Hyaluronate and Sodium Hyaluronate to hydrate skin and soften the look of wrinkles.
This anti-aging serum is formulated around Copper Tripeptide-1 and Lactococcus Ferment Lysate to soften the look of wrinkles and strengthen the skin barrier.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Glycereth-26
1,2-Hexanediol
PPG-26-Buteth-26
PEG-40 Hydrogenated Castor Oil
Sucrose Palmitate
Hydrolyzed Sodium Hyaluronate
Propanediol
Parfum
Sodium Polyacrylate Starch
Glyceryl Linoleate
Tocopheryl Acetate
Sodium Hyaluronate
Sodium Benzoate
Xanthan Gum
Chondrus Crispus Extract
Citric Acid
Disodium EDTA
O-Cymen-5-Ol
Benzyl Alcohol
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Adenosine
Lithothamnion Calcareum Extract
Pentylene Glycol
Sodium Hyaluronate Crosspolymer
Potassium Sorbate
Prunus Amygdalus Dulcis Oil
Sodium Chloride
Dehydroacetic Acid
Sophora Japonica Flower Extract
Glucose
Phenoxyethanol
Potassium Chloride
Calcium Chloride
Magnesium Sulfate
Glutamine
Sodium Phosphate
Ascorbic Acid
Sodium Acetate
Tocopherol
Lysine Hcl
Arginine Hcl
Alanine
Histidine Hcl
Valine
Leucine
Threonine
Isoleucine
Tryptophan
Phenylalanine
Tyrosine
Glycine
Polysorbate 80
Serine
Cystine
Cyanocobalamin
Glutathione
Asparagine
Aspartic Acid
Ornithine Hcl
Glutamic Acid
Nicotinamide Adenine Dinucleotide
Proline
Methionine
Taurine
Hydroxyproline
Glucosamine Hcl
Coenzyme A
Sodium Glucuronate
Thiamine Diphosphate
Retinyl Acetate
Inositol
Niacin
Niacinamide
Pyridoxine Hcl
Biotin
Calcium Pantothenate
Riboflavin
Sodium Tocopheryl Phosphate
Thiamine Hcl
Folic Acid
Water, Glycereth-26, 1,2-Hexanediol, PPG-26-Buteth-26, PEG-40 Hydrogenated Castor Oil, Sucrose Palmitate, Hydrolyzed Sodium Hyaluronate, Propanediol, Parfum, Sodium Polyacrylate Starch, Glyceryl Linoleate, Tocopheryl Acetate, Sodium Hyaluronate, Sodium Benzoate, Xanthan Gum, Chondrus Crispus Extract, Citric Acid, Disodium EDTA, O-Cymen-5-Ol, Benzyl Alcohol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Adenosine, Lithothamnion Calcareum Extract, Pentylene Glycol, Sodium Hyaluronate Crosspolymer, Potassium Sorbate, Prunus Amygdalus Dulcis Oil, Sodium Chloride, Dehydroacetic Acid, Sophora Japonica Flower Extract, Glucose, Phenoxyethanol, Potassium Chloride, Calcium Chloride, Magnesium Sulfate, Glutamine, Sodium Phosphate, Ascorbic Acid, Sodium Acetate, Tocopherol, Lysine Hcl, Arginine Hcl, Alanine, Histidine Hcl, Valine, Leucine, Threonine, Isoleucine, Tryptophan, Phenylalanine, Tyrosine, Glycine, Polysorbate 80, Serine, Cystine, Cyanocobalamin, Glutathione, Asparagine, Aspartic Acid, Ornithine Hcl, Glutamic Acid, Nicotinamide Adenine Dinucleotide, Proline, Methionine, Taurine, Hydroxyproline, Glucosamine Hcl, Coenzyme A, Sodium Glucuronate, Thiamine Diphosphate, Retinyl Acetate, Inositol, Niacin, Niacinamide, Pyridoxine Hcl, Biotin, Calcium Pantothenate, Riboflavin, Sodium Tocopheryl Phosphate, Thiamine Hcl, Folic Acid
Glycerin
Lactococcus Ferment Lysate
Copper Tripeptide-1
Acetyl Hexapeptide-8
Pentapeptide-18
Palmitoyl Tripeptide-1
Palmitoyl Tetrapeptide-7
Palmitoyl Tripeptide-38
Dipeptide Diaminobutyroyl Benzylamide Diacetate
Acetylarginyltryptophyl Diphenylglycine
Allantoin
Histidine
Arginine
Trehalose
Fructose
Maltose
Urea
Sodium PCA
PCA
Sodium Lactate
Hydroxypropyl Cyclodextrin
Sodium Hydroxide
Butylene Glycol
Acacia Senegal Gum
Carbomer
Polysorbate 20
Dimethyl Isosorbide
Caprylyl Glycol
Ethylhexylglycerin
Chlorphenesin
Water, Glycerin, Lactococcus Ferment Lysate, Copper Tripeptide-1, Acetyl Hexapeptide-8, Pentapeptide-18, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-38, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Acetylarginyltryptophyl Diphenylglycine, Sodium Hyaluronate Crosspolymer, Sodium Hyaluronate, Allantoin, Glycine, Alanine, Serine, Valine, Isoleucine, Proline, Threonine, Histidine, Phenylalanine, Arginine, Aspartic Acid, Trehalose, Fructose, Glucose, Maltose, Urea, Sodium PCA, PCA, Sodium Lactate, Citric Acid, Hydroxypropyl Cyclodextrin, Sodium Chloride, Sodium Hydroxide, Butylene Glycol, Pentylene Glycol, Acacia Senegal Gum, Xanthan Gum, Carbomer, Polysorbate 20, Dimethyl Isosorbide, Sodium Benzoate, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol, Chlorphenesin
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Alanine is an amino acid and is already found in the human body. Our skin uses alanine to build collagen, elastin, and keratin.
Aspartic Acid is an amino acid that our bodies produce naturally. It is an antioxidant.
Our body uses Aspartic Acid to help build collagen and elastin. It also plays a role in hydrating skin.
Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
In skincare formulas, citric acid can:
While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.
However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is unique, we recommend a patch test if you are unsure.
Glucose is a simple sugar (a monosaccharide). In skincare, it is mostly a humectant and skin conditioning agent.
Mechanistically, it has multiple hydroxyl groups that hydrogen-bond to water. This pulls moisture into the upper layers of skin to keep the surface soft and hydrated.
It's worth knowing sugars are already a natural component of the skin's NMF (natural moisturizing factor) so it's a molecule that your stratum corneum is well-acquainted with.
Just so you know, glucose is hydrophilic (water-loving) and the stratum corneum is a strong barrier to hydrophilic compounds. This just means penetration is slow and most of the action is happening on the surface.
Gram-to-gram, glucose is not as efficient as a humectant as glycerin. This is why you'll likely see glycose paired with stronger humectants for a bigger hydration payoff.
In skincare, glucose is typically derived from corn or other starch sources.
Glycine is the smallest amino acid and a key building block of collagen. It's part if your skin's Natural Moisturizing Factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.
A study from 2022 found that an amino acid complex featuring taurine, arginine, and glycine significantly reduced skin irritation, improved redness, and accelerated the skin repair process.
Isoleucine is an amino acid that helps reinforce our skin barrier. This amino acid plays a role in creating protein for the body.
Fun fact: Isoleucine is found in meat, fish, dairy, legumes, and nuts.
Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:
Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.
On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.
Typical use levels in a formula run about 1-5%.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Phenylalanine is an amino acid. It is a skin soothing and hydrating ingredient. Amino acids play a crucial role in wound healing and skin hydration.
This ingredient is also used to help even out skin tone due to its ability to disrupt the melanin production process.
Two structures of phenylalanine exist: L-phenylalanine and D-phenylalanine. L-phenylalanine is essential, this means our bodies cannot produce it naturally and we must get it from foods. Our bodies convert D-phenylalanine to neurotransmitters, and D-phenylalanine is found in our bodies naturally.
Some foods that contain L-phenylalanine include eggs, soybeans, beef, milk.
Proline is a non-essential amino acid, meaning your body can make it on its own. In skincare, it is a skin conditioning ingredient that keeps skin soft and hydrated.
It makes up about 23% of the collagen molecule (collagen is the protein responsible for keeping your skin firm) and is involved in your skin's natural hyaluronic acid production. When applied topically, proline can penetrate the skin fairly well due to its small molecular size.
Reviews of this ingredient have found it to be neither a dermal irritant nor a sensitizer.
Fun fact: Proline can be found in protein-rich foods like meat, fish, eggs, and dairy.
Serine is a non-essential amino acid (your body makes it on its own!). It is a major player in your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.
Serine is one of your NMF's most abundant components that works as a skin-identical humectant. Its hydroxyl group grabs onto water molecules to boost hydration without any heaviness or occlusion.
Research on a hydrogel with serine confirmed this serine got delivered to your stratum corneum and demonstrated enhanced skin moisturization.
Interestingly serine also helps your skin produce filaggrin, a protein that keeps your skin barrier strong and used to create collagen.
Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.
Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.
Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.
It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.
Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.
We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.
Chances are, you eat sodium chloride every day. Sodium Chloride is also known as table salt. This ingredient has many purposes in skincare: thickener, emulsifier, and exfoliator.
You'll most likely find this ingredient in cleansers where it is used to create a gel-like texture. As an emulsifier, it also prevents ingredients from separating.
You might see people debate whether Sodium Chloride is comedogenic, but there actually haven't been any comedogenic tests done on it. Either way, the overall formulation of a product matters a lot more than any single ingredient.
You might see this ingredient used in scrubs as a primary exfoliating ingredient.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Sodium Hyaluronate Crosspolymer is a crosslinked version of sodium hyaluronate. This just means it's linked into a 3D mesh network that lets it be more stable and sit on skin as a cohesive, gel-like film rather than sinking into skin.
A 2016 human skin study found crosslinked HA increased epidermal water content by 7.6% over the control group and reduced transepidermal water loss by 27.8%.
A follow-up clinical trial found that a topical crosslinked HA serum applied after fillers, microneedling, or chemical peels was well-tolerated and enhanced skin quality at 14 / 28 days.
More recent research suggests that concentrations as low as 0.03% can act as a penetration enhancer for other skincare actives.
Threonine is an amino-acid. It helps hydrate the skin and has antioxidant benefits.
Our skin uses threonine for creating collagen and elastin. Humans are not able to create threonine and must get it through eating foods such as fish, lentils, poultry, sesame seeds, and more.
Valine is one of the essential amino acids (meaning your body can't make it on its own and has to get it from food).
In skincare, it's usually synthetically-made or pulled from plant proteins like soy.
It's one of the small building blocks that make up your skin's natural moisturizing factor (NMF), or the built-in system that helps skin hold onto water. So its main job in a formula is to give the skin gentle hydration and help it feel more comfortable.
Typical amounts are very tiny: roughly 0.00004%-0.5% in leave on products and up to 1% in rinse-off ones.
The Cosmetic Ingredient Review panel has looked at this ingredient and found no evidence of it being a skin irritant or allergen at cosmetic levels.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.