Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

First Aid Beauty Eye Duty Niacinamide Brightening Eye Cream Versus Estée Lauder Advanced Night Repair Eye Supercharged Complex

First Aid Beauty Eye Duty Niacinamide Brightening Eye Cream Versus Estée Lauder Advanced Night Repair Eye Supercharged Complex This brightening eye moisturizer is formulated around Niacinamide and Sodium Ascorbyl Phosphate to brighten dull-looking skin and fad

First Aid Beauty Eye Duty Niacinamide Brightening Eye Cream Versus Estée Lauder Advanced Night Repair Eye Supercharged Complex

This brightening eye moisturizer is formulated around Niacinamide and Sodium Ascorbyl Phosphate to brighten dull-looking skin and fade the look of dark spots.

This barrier-repair eye moisturizer is formulated around Bifida Ferment Lysate and Caffeine to strengthen the skin barrier and soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Dimethicone

Glycerin

Maris Aqua

Butylene Glycol

Niacinamide

Polysilicone-11

Caprylic/Capric Triglyceride

Mica

Panthenol

Gigartina Stellata/Kappaphycus Alvarezii Extract

Sodium Ascorbyl Phosphate

Coffea Arabica Seed Extract

Sodium Hyaluronate

Caffeine

Cucurbita Pepo Seed Extract

Corallina Officinalis Extract

Glycyrrhiza Glabra Root Extract

Chrysanthemum Parthenium Extract

Camellia Sinensis Leaf Extract

Tocopherol

Phytosteryl/Octyldodecyl Lauroyl Glutamate

Sodium Acrylates Copolymer

Hydroxyacetophenone

Glyceryl Polyacrylate

Squalane

Hydrogenated Polycyclopentadiene

Polyacrylate Crosspolymer-6

Lecithin

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Caprylyl Glycol

Linoleic Acid

Phytosteryl Canola Glycerides

Silica

Hexylene Glycol

Palmitic Acid

Oleic Acid

Stearic Acid

Sorbitan Isostearate

Polysorbate 60

Triolein

T-Butyl Alcohol

Phenoxyethanol

Sodium Benzoate

Potassium Sorbate

Citric Acid

CI 77891

CI 77491

Water, Dimethicone, Glycerin, Maris Aqua, Butylene Glycol, Niacinamide, Polysilicone-11, Caprylic/Capric Triglyceride, Mica, Panthenol, Gigartina Stellata/Kappaphycus Alvarezii Extract, Sodium Ascorbyl Phosphate, Coffea Arabica Seed Extract, Sodium Hyaluronate, Caffeine, Cucurbita Pepo Seed Extract, Corallina Officinalis Extract, Glycyrrhiza Glabra Root Extract, Chrysanthemum Parthenium Extract, Camellia Sinensis Leaf Extract, Tocopherol, Phytosteryl/Octyldodecyl Lauroyl Glutamate, Sodium Acrylates Copolymer, Hydroxyacetophenone, Glyceryl Polyacrylate, Squalane, Hydrogenated Polycyclopentadiene, Polyacrylate Crosspolymer-6, Lecithin, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Caprylyl Glycol, Linoleic Acid, Phytosteryl Canola Glycerides, Silica, Hexylene Glycol, Palmitic Acid, Oleic Acid, Stearic Acid, Sorbitan Isostearate, Polysorbate 60, Triolein, T-Butyl Alcohol, Phenoxyethanol, Sodium Benzoate, Potassium Sorbate, Citric Acid, CI 77891, CI 77491

Methyl Trimethicone

Bifida Ferment Lysate

Dimethicone/Vinyl Dimethicone Crosspolymer

Propanediol

Sucrose

Petrolatum

Polysorbate 40

Trehalose

Algae Extract

Morus Bombycis Root Extract

Scutellaria Baicalensis Root Extract

Lactobacillus Ferment

Triticum Vulgare Germ Extract

Acrylamide/Sodium Acryloyldimethyltaurate Copolymer

Betula Alba Bark Extract

Hydrolyzed Algin

Poria Cocos Sclerotium Extract

Jojoba Alcohol

Ethylhexylglycerin

Glycine Soja Seed Extract

Isopropyl Jojobate

Jojoba Esters

Isohexadecane

Faex Extract

Hydrogenated Lecithin

Hordeum Vulgare Extract

PEG/PPG-18/18 Dimethicone

Cholesterol

Anthemis Nobilis Flower Extract

Tocopheryl Acetate

Sodium Rna

Polysorbate 80

Phytosphingosine

Potassium Sulfate

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Tripeptide-32

Tromethamine

Disodium EDTA

BHT

CI 77492

CI 77499

Methyl Trimethicone, Water, Bifida Ferment Lysate, Dimethicone, Dimethicone/Vinyl Dimethicone Crosspolymer, Propanediol, Sucrose, Petrolatum, Polysorbate 40, Trehalose, Algae Extract, Morus Bombycis Root Extract, Scutellaria Baicalensis Root Extract, Lactobacillus Ferment, Triticum Vulgare Germ Extract, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Betula Alba Bark Extract, Hydrolyzed Algin, Poria Cocos Sclerotium Extract, Jojoba Alcohol, Ethylhexylglycerin, Glycine Soja Seed Extract, Isopropyl Jojobate, Jojoba Esters, Isohexadecane, Faex Extract, Hydrogenated Lecithin, Hordeum Vulgare Extract, PEG/PPG-18/18 Dimethicone, Cholesterol, Anthemis Nobilis Flower Extract, Tocopheryl Acetate, Sodium Rna, Caffeine, Polysorbate 80, Caprylyl Glycol, Phytosphingosine, Squalane, Potassium Sulfate, Sodium Hyaluronate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tripeptide-32, Butylene Glycol, Tromethamine, Disodium EDTA, BHT, Phenoxyethanol, CI 77491, CI 77492, CI 77499

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Caffeine is a naturally occurring plant compound found in coffee beans, tea leaves, cocoa pods, and guarana.

As an antioxidant, caffeine protects your skin from free radical damage caused by UV exposure and envionrmnetal stressors.

Early research also shows that caffeine can help calm redness, soothe irritated skin, and support hair growth by stimulating microcirculation in the scalp.

You might have seen eye creams marketing caffeine as a depuffing ingredient. This is because it is a vasoconstrictor meaning it can temporarily constrict blood vessels, though clinical evidence for this specific use is still limited.

Most skincare products contain this ingredient at concentrations between 1-6%. It is able to penetrate skin easily regardless of skin type or thickness.

Just so you know, a very small number of case reports describe caffeine-induced allergy. This ingredient is generally well-tolerated, non-irritating, and non-sensitizing for the majority of people.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Ci 77491 is also hydrated iron III oxide. It's sole purpose is to give a red/pink hue to products.

Iron III oxides are classified as inorganic chemicals for coloring.

Synthetically created Ci 77491 is considered safer than those naturally found. This is because the synthetically created version may contain less impurities. Iron oxides are generally non-toxic and non-allergenic.

Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.

What it does:

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Squalane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).

It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.

This is due to how structurally similar it is to what your skin already produces.

Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.

Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.

No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).

Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.

The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.

Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.

A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.

The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

First Aid Beauty Ultra Repair Tinted Moisturizer - SPF 30Ingredients explained

  1. 01The famous Avobenzone. It is a special snowflake as it is the only globally available chemical sunscreen agent that provides proper UVA protection (in the US, new generation sunscreen agents are not approved because of impossible FDA regulations). I…
  2. 02It gives very good protection across the whole UVA range (310-400 nm that is both UVA1 and UVA2) with a peak protection at 360 nm. The problem with it, though, is that it is not photostable and degrades in the sunlight. Wikipedia says that avobenzon…
  3. 03Expand to read more
  4. 04The cosmetic's industry is trying to solve the problem by combining avobenzone with other UV filters that enhance its stability (like octocrylene, Tinosorb S or Ensulizole) or by encapsulating it and while both solutions help, neither is perfect. In…
  5. 05As for safety, avobenzone has a pretty good safety profile. It counts as non-irritating, and unlike some other chemical sunscreens, it shows no estrogenic effect. The maximum concentration of avobenzone permitted is 5% in the EU and 3% in the US.
  6. 06A clear, oil-soluble, "cosmetically-elegant" liquid that is the most commonly used chemical sunscreen. It absorbs UVB radiation (at wavelengths: 280-320 nm) with a peak protection at 310nm.
  7. 07It only protects against UVB and not UVA rays (the 320-400 nm range) – so always choose products that contain other sunscreens too. It is not very stable either, when exposed to sunlight, it kind of breaks down and loses its effectiveness (not insta…
  8. 08Regarding safety, there are also some concerns around Octinoxate. In vitro (made in the lab not on real people) and animal studies have shown that it may produce hormonal (estrogen-like) effects. Do not panic, the studies were not conducted under re…
  9. 09Overall, Ethylhexyl Methoxycinnamate is an old-school chemical sunscreen agent. There are plenty of better options for sun protection today, but it is considered "safe as used" (and sunscreens are pretty well regulated) and it is available worldwide…
  10. 10A colorless to light yellowish oily liquid that works as a UVB (280-320nm) sunscreen filter with a peak absorbance at 306 nm. It's not a strong filter in itself, it's always used in combination with other sunscreen agents to further enhance the SPF …
  11. 11It has a good safety profile and is allowed to be used at a max concentration of 5% both in the US and in Europe (10% is allowed in Japan).
  12. 12An oil-soluble chemical sunscreen agent that protects skin in the UVB and somewhat in the UVA II range with a peak absorption of 304 nm. Its protection is not strong enough on its own but it is quite photostable (loses 10% of SPF protection in 95 mi…
  13. 13Octocrylene's safety profile is generally quite good, though a review study in Contact Dermatitis reports an "increasing number of patients with photo contact allergy to octocrylene." Mainly adults with ketoprofen-sensitivity and children with sensi…
  14. 14Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product.
  15. 15It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water.
  16. 16Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying.
  17. 17One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time.
  18. 18A super commonly used 5 unit long, cyclic structured silicone that is water-thin and does not stay on the skin but evaporates from it (called volatile silicone). Similar to other silicones, it gives skin and hair a silky, smooth feel.
  19. 19It's often combined with the non-volatile (i.e. stays on the skin) dimethicone as the two together form a water-resistant, breathable protective barrier on the skin without a negative tacky feel.
  20. 20Probably the most common silicone of all. It is a polymer (created from repeating subunits) molecule and has different molecular weight and thus different viscosity versions from water-light to thick liquid.
Source · incidecoder.com
02

Product index

Related product references

03

Comparison edit

Read side by side