Skin science article
First Aid Beauty Firming Collagen Cream With Peptides + Niacinamide Versus First Aid Beauty Bounce-Boosting Serum with Collagen + Peptides
First Aid Beauty Firming Collagen Cream With Peptides + Niacinamide Versus First Aid Beauty Bounce-Boosting Serum with Collagen + Peptides This anti-aging moisturizer is formulated around Niacinamide to soften the look of wrinkles and strengthen the skin barri
First Aid Beauty Firming Collagen Cream With Peptides + Niacinamide Versus First Aid Beauty Bounce-Boosting Serum with Collagen + Peptides
This anti-aging moisturizer is formulated around Niacinamide to soften the look of wrinkles and strengthen the skin barrier.
This anti-aging serum is formulated around Bakuchiol to soften the look of wrinkles.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Glycerin
Niacinamide
C12-15 Alkyl Benzoate
Caprylic/Capric Triglyceride
Palmitic Acid
Stearic Acid
Glyceryl Stearate
Glyceryl Stearate Se
Dimethicone
Cetearyl Alcohol
Panthenol
Colloidal Oatmeal
Collagen
Squalane
Ceramide NP
Hexapeptide-9
Butyrospermum Parkii Butter
Allantoin
Saccharomyces Ferment
Caprylyl Glycol
Lauroyl Lysine
Butylene Glycol
Tetrasodium Glutamate Diacetate
Xanthan Gum
Phenoxyethanol
Sodium Hydroxide
Water, Glycerin, Niacinamide, C12-15 Alkyl Benzoate, Caprylic/Capric Triglyceride, Palmitic Acid, Stearic Acid, Glyceryl Stearate, Glyceryl Stearate Se, Dimethicone, Cetearyl Alcohol, Panthenol, Colloidal Oatmeal, Collagen, Squalane, Ceramide NP, Hexapeptide-9, Butyrospermum Parkii Butter, Allantoin, Saccharomyces Ferment, Caprylyl Glycol, Lauroyl Lysine, Butylene Glycol, Tetrasodium Glutamate Diacetate, Xanthan Gum, Phenoxyethanol, Sodium Hydroxide
Propanediol
Dicaprylyl Carbonate
C9-12 Alkane
Soluble Collagen
Hydrolyzed Collagen
Pentapeptide-34 Trifluoroacetate
Hydrolyzed Sodium Hyaluronate
Acetyl Hydroxyproline
Sodium Hyaluronate
Bakuchiol
Chrysanthemum Parthenium Extract
Camellia Sinensis Leaf Extract
Glycyrrhiza Glabra Root Extract
Chlorella Vulgaris Extract
Tocopherol
Coco-Caprylate/Caprate
Glycine
Histidine
Hydrolyzed Corn Protein
Alanine
Sorbitan Olivate
Isoleucine
Leucine
Lysine
Phenylalanine
Proline
Serine
Arginine
Cetearyl Olivate
Threonine
Tyrosine
Valine
Aspartic Acid
Carbomer
Glutamic Acid
Glyceryl Acrylate/Acrylic Acid Copolymer
Potassium Sorbate
Sodium Benzoate
Tetrasodium EDTA
Water, Propanediol, Dicaprylyl Carbonate, Glycerin, C9-12 Alkane, Soluble Collagen, Ceramide NP, Hydrolyzed Collagen, Pentapeptide-34 Trifluoroacetate, Hydrolyzed Sodium Hyaluronate, Acetyl Hydroxyproline, Sodium Hyaluronate, Bakuchiol, Chrysanthemum Parthenium Extract, Camellia Sinensis Leaf Extract, Glycyrrhiza Glabra Root Extract, Chlorella Vulgaris Extract, Tocopherol, Coco-Caprylate/Caprate, Glycine, Histidine, Hydrolyzed Corn Protein, Alanine, Sorbitan Olivate, Isoleucine, Leucine, Lysine, Phenylalanine, Proline, Serine, Arginine, Cetearyl Olivate, Threonine, Tyrosine, Valine, Aspartic Acid, Butylene Glycol, Carbomer, Cetearyl Alcohol, Glutamic Acid, Glyceryl Acrylate/Acrylic Acid Copolymer, Xanthan Gum, Phenoxyethanol, Potassium Sorbate, Sodium Benzoate, Sodium Hydroxide, Tetrasodium EDTA
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.
Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.
This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.
A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.
Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.
Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.
Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.
Cetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier.
Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient.
It plays several roles in a formula:
Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products.
Multiple assessments have found it to be non-irritating and non-sensitizing to most people.
However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers.
Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy.
Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans.
Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients.
This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain lengths that fall within the range that Malassezia can metabolize.
A 2019 study has also observed Malassezia growth in the presence of this ingredient, confirming it to be not-fungal acne safe.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.