Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Galderma Tactupump Forte Versus Paula's Choice 1% Retinol Treatment

Galderma Tactupump Forte Versus Paula's Choice 1% Retinol Treatment This acne treatment is formulated around Benzoyl Peroxide and Adapalene to clear breakouts and refine skin texture. This anti-aging treatment is formulated around Retinol and Tetrahexyldecyl A

Galderma Tactupump Forte Versus Paula's Choice 1% Retinol Treatment

This acne treatment is formulated around Benzoyl Peroxide and Adapalene to clear breakouts and refine skin texture.

This anti-aging treatment is formulated around Retinol and Tetrahexyldecyl Ascorbate to soften the look of wrinkles and refine skin texture.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Benzoyl Peroxide 2.5%

Adapalene 0.3%

Acrylamide/Sodium Acryloyldimethyltaurate Copolymer

Sodium Anisate

Disodium EDTA

Glycerin

Isohexadecane

Poloxamer 124

Polysorbate 80

Propylene Glycol

Sorbitan Oleate

Water

Benzoyl Peroxide 2.5%, Adapalene 0.3%, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Sodium Anisate, Disodium EDTA, Glycerin, Isohexadecane, Poloxamer 124, Polysorbate 80, Propylene Glycol, Sorbitan Oleate, Water

Dimethicone

Butylene Glycol

Isononyl Isononanoate

Castor Isostearate Succinate

Glyceryl Stearate

C12-15 Alkyl Benzoate

Dimethicone Crosspolymer

PEG-33

Polysorbate 20

Behenyl Alcohol

PEG-100 Stearate

Pentaerythrityl Tetraisostearate

Polymethylsilsesquioxane

Tetrahexyldecyl Ascorbate

Retinol

Ceramide Ng

Palmitoyl Tetrapeptide-7

Palmitoyl Hexapeptide-12

Sodium Hyaluronate

Dipotassium Glycyrrhizate

Glycyrrhiza Glabra Root Extract

Avena Sativa Kernel Extract

Arctium Lappa Seed Oil

Salix Alba Extract

Glycine Soja Sterols

Lecithin

Allantoin

Tocopheryl Acetate

Hydrolyzed Soy Protein

Sorbitan Laurate

Acetyl Dipeptide-1 Cetyl Ester

Hydroxyethylcellulose

Palmitoyl Tripeptide-1

Sodium Hydroxide

Tribehenin

Caprylyl Glycol

Ethylhexylglycerin

Pentylene Glycol

PEG-75 Shea Butter Glycerides

PPG-12/Smdi Copolymer

PEG-10 Phytosterol

PEG-8 Dimethicone

PEG-14

Magnesium Aluminum Silicate

Arachidyl Glucoside

Arachidyl Alcohol

Sclerotium Gum

Carbomer

Phenoxyethanol

Benzoic Acid

Water, Dimethicone, Glycerin, Butylene Glycol, Isononyl Isononanoate, Castor Isostearate Succinate, Glyceryl Stearate, C12-15 Alkyl Benzoate, Dimethicone Crosspolymer, PEG-33, Polysorbate 20, Behenyl Alcohol, PEG-100 Stearate, Pentaerythrityl Tetraisostearate, Polymethylsilsesquioxane, Tetrahexyldecyl Ascorbate, Retinol, Ceramide Ng, Palmitoyl Tetrapeptide-7, Palmitoyl Hexapeptide-12, Sodium Hyaluronate, Dipotassium Glycyrrhizate, Glycyrrhiza Glabra Root Extract, Avena Sativa Kernel Extract, Arctium Lappa Seed Oil, Salix Alba Extract, Glycine Soja Sterols, Lecithin, Allantoin, Tocopheryl Acetate, Hydrolyzed Soy Protein, Sorbitan Laurate, Acetyl Dipeptide-1 Cetyl Ester, Disodium EDTA, Hydroxyethylcellulose, Palmitoyl Tripeptide-1, Sodium Hydroxide, Tribehenin, Caprylyl Glycol, Ethylhexylglycerin, Pentylene Glycol, PEG-75 Shea Butter Glycerides, PPG-12/Smdi Copolymer, PEG-10 Phytosterol, PEG-8 Dimethicone, PEG-14, Magnesium Aluminum Silicate, Arachidyl Glucoside, Arachidyl Alcohol, Sclerotium Gum, Carbomer, Phenoxyethanol, Benzoic Acid

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Behenic acid is a long-chain fatty acid with 22 carbon atoms (C22) that is naturally found in moringa, rapeseed, and peanut oil.
  4. 04In skincare, it's about as drama-free as ingredients come. It acts primarily as a texture enhancer, thickener, and opacifying agent that gives richness and viscosity to formulas.
  5. 05On skin, it forms a protective, emollient layer that helps with moisture retention and contributes to barrier integrity.
  6. 06In vitro studies on genotoxicity have come back negative and this ingredient is well-tolerated. Typical use concentrations range from 0.024%-22%.
  7. 07This ingredient may not be fungal acne safe because Behenic acid falls within the C11-24 fatty acid range capable of supporting Malassezia growth.
  8. 08This ceramide helps condition and moisturize skin.
  9. 09It is created by reacting caproic acid and phytosphingosine, two fatty acids.
  10. 10Ceramides work to improve hydration from within. Their lipophilic trait means they are likely to be absorbed into skin but expected to remain in the epidermis (the outer layer of skin).
  11. 11We don't have a description for Caprooyl Sphingosine yet.
  12. 12Ceramide AP is is a skin-identical lipid that mimics what your skin already makes naturally. Ceramides help maintain epidermal integrity and barrier function.
  13. 13You'll often see this ingredient paired with other ceramides (like ceramide NP), cholesterol, or fatty acids because this combination best mimics the natural lipid mix your skin already has.
  14. 14The skin's ability to produce ceramides gets disrupted in skin conditions like eczema. This in turn weakens the skin barrier and applying ceramides topically has been shown to replenish what's been lost to restore barrier function.
  15. 15Most of the studies with Ceramide AP test it as part of a multi-ceramide complex; studies reinforce ceramide AP's role in rebalancing ceramides in skin and improving skin hydration.
  16. 16Ceramide EOP is formally known as Ceramide 1.
  17. 17It is naturally found in skin and part of the intercellular "mortar" holding everything together in your outermost layer.
  18. 18EOP stands for a linked Ester fatty acid, a linked Omega hydroxy fatty acid, and the Phytosphingosine base.
  19. 19What makes Ceramide EOP special is its ultra-long fatty acid chain; this unique structure allows it to bridge the lipid layers in your skin barrier to prevent water loss (something no other ceramide can do).
  20. 20Low levels of Ceramide EOP have been found in people with eczema and psoriasis.
Source · skinsort.com
02

Product index

Related product references

03

Comparison edit

Read side by side