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GHK-Cu 50mg (Copper Peptide)

GHK-Cu 50mg (Copper Peptide) Research Handling Note: For best results in a research setting, allow both the peptide and chosen solvent to reach ambient laboratory temperature before reconstitution. This helps maintain structural integrity during dissolution. *

By Peptide Skincare & Beauty Editorial TeamPublished

GHK-Cu 50mg (Copper Peptide)

Research Handling Note:

For best results in a research setting, allow both the peptide and chosen solvent to reach ambient laboratory temperature before reconstitution. This helps maintain structural integrity during dissolution. *Reconstitution solutions are supplied separately.

Stock: 7907

Model: GHK-Cu 50mg

Molecular Formula: C14H21CuN6O4

SKU: GHK-023

Research Only: Yes

Certificate of analysis

Description

Technical Data

GHK-Cu 50mg - High-Quality Research Peptide

GHK-Cu, a tripeptide first identified in human blood, is known for its unique property of containing copper molecules, which gives it alternate names such as Copper Peptide Repair Complex, Copper Tripeptide-1, and GHK Copper. The presence of copper (Cu) imbues the compound with a distinctive shade of blue, making it identifiable in research settings.

GHK-Cu, we want to clarify that batch colour variations are normal and do not indicate a quality issue. We have been supplying GHK-Cu for many years, and variations from dark blue to lighter shades occur due to different synthesis and environmental factors. The purity and efficacy remain consistently high across batches, and our testing confirms this.

Product Name: GHK-Cu 50mg

Catalogue Number: GHK-023

CAS Number: 49557-75-7

Unit Quantity: 1 vial

Unit Size: 50mg

Form: Lyophilised Solid

Usage and Storage:

GHK-Cu is supplied as a lyophilised solid to ensure maximum stability and ease of use in research environments. For optimal results, consult our website for detailed reconstitution and storage guidelines.

Synthesis and Quality Assurance:

This peptide is meticulously synthesised through a controlled process that ensures high purity, making it suitable for advanced scientific studies. Our commitment to excellence guarantees that each batch undergoes stringent quality control.

Legal and Safety Information:

UK-Peptides provides GHK-Cu strictly for scientific and research use. Our products meet stringent quality standards and comply with all legal requirements. Note: Our peptides, including GHK-Cu, are not intended for human consumption or clinical applications.

Important: UK-Peptides products are sold strictly for research purposes only. Inquiry regarding human consumption is strictly prohibited.

Identification

Molecular Weight (g/mol)

340.38 g/mol

Peptide Sequence

Glycyl-L-histidyl-L-lysine

Physical and Chemical Properties

Molecular Formula

C14H24N6O4

Physical Appearance

Blue lyophilised solid

Form

Sterile filtered white lyophilized (freeze-dried)

Solubility

Aqueous soluble

Appearance

White to off-white lyophilised powder

Melting Point

Not applicable (decomposes before melting)

Analytical and Quality Control

HPLC Result

Shows min 99% Purity

Mass Spectrum

Consistent with structure

Purity %

>99%

Research Use and Safety

Caution

Research use only / Not for human or veterinary use

Intended Use

For laboratory research use only. Not for human or veterinary use.

Hazard Classification

Not classified as hazardous under GHS for research quantities

Storage, Handling and Stability

Storage Temperature, Opened

Lyophilized peptides although stable at room temperature for 3 months, should be stored desiccated below -18°C. Upon reconstitution of the peptide it should be stored at 4°C between 2-21 days and for future use below -18°C.

Storage Temperature, Unopened

-20 °C recommended for long-term storage

Shelf Life

2 years unopened under recommended conditions

Reconstitution Stability

Stable for up to 28 days at 2-8 °C in aqueous solution under sterile conditions

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Can GHK-Cu be used with other active ingredients like Vitamin C or Retinol?

  1. 01Yes, GHK-Cu is generally compatible with many other active ingredients. However, we advise applying GHK-Cu first, allowing it to absorb, before applying stronger actives like high-concentration Vitamin C or Retinol. This approach helps minimize pote…
Source · realpeptides.co ⟶
02

Product index

Related product references

Product

Lovely Southern GHK-Cu Repair Serum

Lovely Southern GHK-Cu Repair Serum Ingredients in Lovely Southern GHK-Cu Repair Serum explained: benefits, concerns, and detailed analysis of 9 ingredients including Water, Sodium Hyaluron…

Source: skinsort.comView reference →
03

Comparison edit

Read side by side

GHK-Cu Studied Osteoarthritis: Comparison of Research Models

In Vitro Chondrocyte Culture IL-1β-stimulated human chondrocytes treated with 5–10 µM GHK-Cu for 24–72 hours 40–60% reduction in IL-6, TNF-α, MMP-1, MMP-3; 35% increase in collagen type II …

GHK-Cu Fine Lines Mechanism: Treatment Options Comparison

GHK-Cu (0.5–2%) Copper delivery to fibroblasts; lysyl oxidase activation +70% type I collagen mRNA 47% MMP-1 reduction Low (chelated copper minimizes free ion exposure) 8–12 weeks with cons…

04

Ask the journal

Related questions

01What If the Lyophilized GHK-Cu Powder Arrived as White or Pale Yellow Instead of Blue?

Contact the supplier immediately—this indicates either incorrect product or degraded peptide. Intact GHK-Cu with chelated copper(II) is blue to blue-violet due to d-d electronic transitions in the copper coordination complex. White powder suggests the peptide is present without copper (it wasn't properly chelated during synthesis), and pale yellow suggests copper has oxidized to Cu(I) or dissociated entirely. Neither variant provides the intended biological activity. Lyophilized GHK CU Cosmetic 5MG should always arrive as a distinctly blue powder—color is the first quality indicator before reconstitution.

Source · realpeptides.co ⟶
02What If My Dark Spots Are Hormonal (Melasma) — Does GHK-Cu Work for That?

GHK-Cu shows mixed results for hormonal melasma. A 2021 retrospective analysis of melasma patients found that GHK-Cu produced meaningful improvement (>25% MASI reduction) in only 38% of hormonal melasma cases compared to 71% of UV-driven cases. The reason: hormonal melasma is driven by oestrogen and progesterone receptor activation in melanocytes, which upregulates melanogenesis through pathways that copper-peptides don't effectively modulate. Tranexamic acid (oral or topical) combined with GHK-Cu performs better. The tranexamic acid blocks plasmin-mediated melanocyte activation while GHK-Cu addresses oxidative stress. If you've tried GHK-Cu alone for melasma without results, that's the mechanism gap. Add tranexamic acid or consult a dermatologist about combination protocols.

Source · realpeptides.co ⟶
03What if I want to compare GHK-Cu to retinoids or vitamin C?

Different mechanisms, non-overlapping benefits. Retinoids (tretinoin, adapalene) increase cell turnover and upregulate retinoic acid receptors; vitamin C (L-ascorbic acid) acts as a cofactor for prolyl hydroxylase in collagen synthesis. GHK-Cu delivers copper for metalloproteinase regulation and SOD mimetic activity. None of these overlap mechanistically. Comparative studies suggest additive effects when combined, though no published trials test GHK-Cu + retinoid formulations due to pH incompatibility (retinoids require pH 5.5–6.0; GHK-Cu is most stable at pH 7.0–7.4). Layering them in separate application steps may preserve both activities.

Source · realpeptides.co ⟶
04What If I Stored Reconstituted GHK-Cu in a Refrigerator with Open Ethanol Bottles?

Check your vial seal integrity first. If you used a standard rubber stopper without additional sealing (crimp cap, parafilm), ethanol vapour contamination is likely after 2–3 weeks. Run a simple visual check: does the solution show any discolouration (pale blue tint) or particulate matter? That's free copper precipitation. If yes, discard it. If the solution appears clear and your storage duration was under 14 days, you can likely still use it. But tighten your storage protocol going forward. Seal all peptide vials with parafilm or switch to crimp-top vials, and store alcohol reagents in a separate area.

Source · realpeptides.co ⟶
05What If Topical Application Isn't Delivering Results?

The evidence suggests occlusive dressing significantly improves peptide retention. In the Cincinnati replication trial, participants using occlusion (covering the application site with a hydrocolloid patch for 6 hours post-application) showed 3.2× greater collagen response than those using open-air application. The mechanism: reduced transepidermal water loss slows peptide clearance via dermal capillaries, extending contact time with target fibroblasts. If you're testing topical protocols, occlusion is the single variable most likely to bridge the animal-human efficacy gap.

Source · realpeptides.co ⟶
05

Source shelf

Research & excerpts

Research note

Why Top Researchers Choose GHK-CU 50mg

In the world of peptide research, few compounds generate as much consistent interest as GHK-Cu. This naturally occurring copper peptide complex, composed of the amino acids glycyl-L-histidyl-L-lysine, is a cornerstone of studies focused on cellular regeneration, skin health, and anti-inflammatory processes. For labs across Oakland and beyond, securing a reliable supply of GHK-CU 50mg is essential for achieving replicable and meaningful results. The fascination with GHK-Cu stems from its profound biological relevance. It's a key player in modulating gene expression, capable of influencing pathways related to tissue repair and antioxidant defense. Researchers are actively investigating its potential to stimulate collagen and elastin production, which is why it's a primary focus in dermatological and anti-aging studies. Its ability to attract immune cells and accelerate wound healing processes makes it a valuable tool for regenerative medicine research. It’s not just a single-function peptide; it's a complex signaling molecule that offers a wide field for scientific discovery. However, the potential of any study is directly tied to the quality of the materials used. This is where Real Peptides sets the standard. We understand that for researchers in Oakland, 'good enough' simply isn't an option. Our GHK CU Copper Peptide is synthesized to achieve over 99% purity, which we verify through independent, third-party lab testing. Every vial of GHK-CU 50mg we ship is lyophilized (freeze-dried) to ensure maximum stability and shelf-life, preserving its integrity from our facility to your lab bench. This commitment to excellence is what distinguishes us from other suppliers. While some may cut corners on verification, we believe in complete transparency. We know your work is too important to leave to chance. Our process ensures that the compound you receive is precisely what you ordered, free from impurities that could compromise your data. This allows you to conduct your experiments with the highest degree of confidence, knowing your results are built on a foundation of quality. Key areas of research for GHK-CU 50mg in 2026 include: Cellular Regeneration and Wound Healing: Investigating its role in stimulating fibroblast proliferation and angiogenesis in in-vitro models. Dermatological and Anti-Aging Studies: Analyzing its impact on gene expression related to skin matrix proteins like collagen. Anti-Inflammatory Pathways: Exploring its potential to modulate cytokine activity and reduce oxidative stress in cell cultures. At Real Peptides, we're more than just a supplier; we're a partner to the scientific community in Oakland. We provide the high-purity tools, like our premium GHK-CU 50mg, that empower you to conduct groundbreaking research. You can explore our dedication to quality across our entire collection of peptides and see why so many labs trust us for their most critical projects. Explore High-Purity Research Peptides

Source · realpeptides.co ⟶

Research note

GHK-Cu 50mg Mesa | High-Purity Copper Peptide Research

Mesa researchers require compounds of the highest caliber for meaningful results. When your study involves GHK-Cu 50mg, purity isn't just a goal—it's a necessity. Real Peptides provides lab-verified, high-purity copper peptides to ensure your work is precise and reproducible.

Source · realpeptides.co ⟶

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