Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Good Molecules Hydrating Gel Moisturizer With Electrolytes Versus First Aid Beauty Hydrating Dewy Gel Cream

Good Molecules Hydrating Gel Moisturizer With Electrolytes Versus First Aid Beauty Hydrating Dewy Gel Cream This calming moisturizer is formulated around Chondrus Crispus Extract and Pseudoalteromonas Ferment Extract to calm redness and hydrate skin. This barr

Good Molecules Hydrating Gel Moisturizer With Electrolytes Versus First Aid Beauty Hydrating Dewy Gel Cream

This calming moisturizer is formulated around Chondrus Crispus Extract and Pseudoalteromonas Ferment Extract to calm redness and hydrate skin.

This barrier-repair moisturizer is formulated around Squalane and Niacinamide to strengthen the skin barrier and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Propanediol

Glycerin

Chondrus Crispus Extract

Carrageenan

Sea Salt

Pseudoalteromonas Ferment Extract

Sodium Levulinate

Xylitol

Betaine

Inositol

Ectoin

Sodium Benzoate

1,2-Hexanediol

Xanthan Gum

Dipotassium Glycyrrhizate

Pentylene Glycol

Hydroxyacetophenone

Magnesium Aspartate

Zinc Gluconate

Citric Acid

Arginine

Copper Gluconate

Sodium Hyaluronate

Water, Propanediol, Glycerin, Chondrus Crispus Extract, Carrageenan, Sea Salt, Pseudoalteromonas Ferment Extract, Sodium Levulinate, Xylitol, Betaine, Inositol, Ectoin, Sodium Benzoate, 1,2-Hexanediol, Xanthan Gum, Dipotassium Glycyrrhizate, Pentylene Glycol, Hydroxyacetophenone, Magnesium Aspartate, Zinc Gluconate, Citric Acid, Arginine, Copper Gluconate, Sodium Hyaluronate

Squalane

Dimethicone

Phenyl Trimethicone

Niacinamide

Polyglyceryl-3 Polydimethylsiloxyethyl Dimethicone

Ceramide NP

Colloidal Oatmeal

Tocopherol

Sorbitan Isostearate

Decyl Glucoside

Sodium Acryloyldimethyltaurate/Vp Crosspolymer

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Caprylyl Glycol

Ethylhexylglycerin

Butylene Glycol

Dimethicone/Polyglycerin-3 Crosspolymer

Glyceryl Glucoside

Dimethiconol

Polysilicone-11

Hexylene Glycol

Phenoxyethanol

Polysorbate 60

Water, Glycerin, Squalane, Dimethicone, Phenyl Trimethicone, Betaine, Niacinamide, Pentylene Glycol, Polyglyceryl-3 Polydimethylsiloxyethyl Dimethicone, Propanediol, Sodium Hyaluronate, Ceramide NP, Colloidal Oatmeal, Tocopherol, Sorbitan Isostearate, Decyl Glucoside, Sodium Acryloyldimethyltaurate/Vp Crosspolymer, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Caprylyl Glycol, Ethylhexylglycerin, Butylene Glycol, Dimethicone/Polyglycerin-3 Crosspolymer, Glyceryl Glucoside, Dimethiconol, Polysilicone-11, 1,2-Hexanediol, Hydroxyacetophenone, Hexylene Glycol, Phenoxyethanol, Polysorbate 60

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Betaine is a humectant. Like hyaluronic acid, it helps attract and retain moisture in the skin. It’s known for being gentle and for helping the skin maintain balanced hydration.

Betaine is mainly used to improve hydration and support calmer skin. It helps skin cells regulate water balance because it functions as an osmolyte.

Some studies suggest betaine may support making skin tone more even.

Fun fact: Betaine naturally exists in the skin and the body. In cosmetic products, it can be either plant-derived (most commonly from sugar beets) or synthetically produced for consistency and stability.

Betaine is also known as trimethylglycine.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Hydroxyacetophenone is a small phenolic molecule that earns its place in a formulas as an antioxidant and preservative booster.

As a phenol, it is able to neutralize free radicals to protect both the product and the skin from oxidative stress.

Though it can't kill microbes on its own, it works as a good supporting agent when combined with other preservatives like Phenoxyethanol or 1,2-Hexanediol.

This ingredient naturally occurs as piceol in Norwegian spruce needles (~0.4-1.1% dry weight and in cloudberries). Though the cosmetic-grade material is synthesized for purity and consistency.

You'll usually see it used at low levels and suppliers recommend up to 1% added to a water phase.

Safety testing was done at concentrations like 0.05% in SPF products and 0.5% in a Human Repeated Insult Patch Test. The safety evidence is assuring; this ingredient is safe for cosmetics in current use and also holds safety status as a food flavoring as well.

An honest caveat: the "soothing" and "anti-inflammatory" claims come mostly from supplier marketing rather than published clinical trials. The Cosmetic Ingredient Review's own literature search found no useful efficacy studies on this ingredient.

So the antioxidant and preservative-boosting roles are the well supported ones while the calming benefit is plausible but thinly evidenced.

Overall, this is a well-tolerated, low-irritation multitasker that quietly helps a formula stay fresh and stable.

Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:

Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.

On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.

Typical use levels in a formula run about 1-5%.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
  4. 04Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
  5. 05However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
  6. 06Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
  7. 07In skincare formulas, citric acid can:
  8. 08While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
  9. 09Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
  10. 10Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.
  11. 11However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's…
  12. 12Coco-Glucoside is a surfactant, or a cleansing ingredient. It is made from glucose and coconut oil.
  13. 13Surfactants help gather dirt, oil, and other pollutants from your skin to be rinsed away.
  14. 14This ingredient is considered gentle and non-comedogenic. However, it may still be irritating for some.
  15. 15Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
  16. 16Topically, glycerin does several things at once:
  17. 17Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
  18. 18Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
  19. 19This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
  20. 20Just know very high concentrations (>40%) can feel tacky in low humidity.
Source · skinsort.com
02

Product index

Related product references

03

Comparison edit

Read side by side