Good Molecules Super Peptide Serum Versus Skin Deva 20% Argireline + Matrixyl 3000 + Hyaluronic Acid Serum

Good Molecules Super Peptide Serum Versus Skin Deva 20% Argireline + Matrixyl 3000 + Hyaluronic Acid Serum

This anti-aging serum is formulated around Acetyl Hexapeptide-8 and Acetyl Octapeptide-3 to soften the look of wrinkles and strengthen the skin barrier.

This anti-aging serum is formulated around Acetyl Hexapeptide-8 and Matrixyl 3000 to soften the look of wrinkles and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

No concerns

Ingredients Side-by-side

Water

Propanediol

Glycerin

Ammonium Acryloyldimethyltaurate/Vp Copolymer

1,2-Hexanediol

Diheptyl Succinate

Capryloyl Glycerin/Sebacic Acid Copolymer

Glycine

Xanthan Gum

Ethylhexylglycerin

Caprylyl Glycol

Acetyl Hexapeptide-8

Acetyl Octapeptide-3

Sodium Hyaluronate

Copper Tripeptide-1

Tocopherol

Water, Propanediol, Glycerin, Ammonium Acryloyldimethyltaurate/Vp Copolymer, 1,2-Hexanediol, Diheptyl Succinate, Capryloyl Glycerin/Sebacic Acid Copolymer, Glycine, Xanthan Gum, Ethylhexylglycerin, Caprylyl Glycol, Acetyl Hexapeptide-8, Acetyl Octapeptide-3, Sodium Hyaluronate, Copper Tripeptide-1, Tocopherol

Matrixyl 3000

Aloe Barbadensis Sprout

Hyaluronic Acid

Benzyl Alcohol

Dehydroacetic Acid

Water, Acetyl Hexapeptide-8, Matrixyl 3000, Aloe Barbadensis Sprout, Glycerin, Hyaluronic Acid, Benzyl Alcohol, Dehydroacetic Acid

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative".

It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time.

The comparison to Botox does have limits because the molecule is water-loving and relatively large.

Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles.

So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging.

A 12 week human study of a multi-ingredient regimen containing this ingredient saw:

While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone).

Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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