Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Good Molecules Super Peptide Serum Versus Sulwhasoo Concentrated Ginseng Renewing Rescue Ampoule

Good Molecules Super Peptide Serum Versus Sulwhasoo Concentrated Ginseng Renewing Rescue Ampoule This anti-aging serum is formulated around Acetyl Hexapeptide-8 and Acetyl Octapeptide-3 to soften the look of wrinkles and strengthen the skin barrier. This anti-

Good Molecules Super Peptide Serum Versus Sulwhasoo Concentrated Ginseng Renewing Rescue Ampoule

This anti-aging serum is formulated around Acetyl Hexapeptide-8 and Acetyl Octapeptide-3 to soften the look of wrinkles and strengthen the skin barrier.

This anti-aging ampoule is formulated around Adenosine and Panax Ginseng Root Extract to soften the look of wrinkles and calm redness.

What's inside

Key Ingredients

Benefits

Concerns

No concerns

Ingredients Side-by-side

Water

Propanediol

Glycerin

Ammonium Acryloyldimethyltaurate/Vp Copolymer

1,2-Hexanediol

Diheptyl Succinate

Capryloyl Glycerin/Sebacic Acid Copolymer

Glycine

Xanthan Gum

Ethylhexylglycerin

Caprylyl Glycol

Acetyl Hexapeptide-8

Acetyl Octapeptide-3

Sodium Hyaluronate

Copper Tripeptide-1

Tocopherol

Water, Propanediol, Glycerin, Ammonium Acryloyldimethyltaurate/Vp Copolymer, 1,2-Hexanediol, Diheptyl Succinate, Capryloyl Glycerin/Sebacic Acid Copolymer, Glycine, Xanthan Gum, Ethylhexylglycerin, Caprylyl Glycol, Acetyl Hexapeptide-8, Acetyl Octapeptide-3, Sodium Hyaluronate, Copper Tripeptide-1, Tocopherol

Butylene Glycol

PEG/PPG-17/6 Copolymer

Dipropylene Glycol

Polysorbate 80

PEG-150 Distearate

Diethoxyethyl Succinate

Bis-PEG-18 Methyl Ether Dimethyl Silane

Polysorbate 20

Olive Oil PEG-8 Esters

Parfum

Dipotassium Glycyrrhizate

Pentylene Glycol

Adenosine

Disodium EDTA

Methoxy PEG-114/Polyepsilon Caprolactone

Sodium Chloride

Panax Ginseng Root Extract

Achillea Millefolium Extract

Honey

Rehmannia Glutinosa Root Extract

Hydrolyzed Ginseng Saponins

Paeonia Lactiflora Root Extract

Lilium Candidum Bulb Extract

Polygonatum Odoratum Rhizome Extract

Phenoxyethanol

Nelumbo Nucifera Flower Extract

BHT

Glycyrrhiza Glabra Root Extract

Acetyl Heptapeptide-4

Sodium Hydroxide

Water, Butylene Glycol, Glycerin, PEG/PPG-17/6 Copolymer, Dipropylene Glycol, Polysorbate 80, 1,2-Hexanediol, PEG-150 Distearate, Diethoxyethyl Succinate, Bis-PEG-18 Methyl Ether Dimethyl Silane, Polysorbate 20, Olive Oil PEG-8 Esters, Parfum, Dipotassium Glycyrrhizate, Pentylene Glycol, Ethylhexylglycerin, Adenosine, Disodium EDTA, Methoxy PEG-114/Polyepsilon Caprolactone, Xanthan Gum, Sodium Chloride, Panax Ginseng Root Extract, Achillea Millefolium Extract, Honey, Rehmannia Glutinosa Root Extract, Hydrolyzed Ginseng Saponins, Paeonia Lactiflora Root Extract, Lilium Candidum Bulb Extract, Polygonatum Odoratum Rhizome Extract, Phenoxyethanol, Nelumbo Nucifera Flower Extract, BHT, Glycyrrhiza Glabra Root Extract, Tocopherol, Caprylyl Glycol, Acetyl Heptapeptide-4, Acetyl Hexapeptide-8, Sodium Hydroxide, Acetyl Octapeptide-3

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative".

It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time.

The comparison to Botox does have limits because the molecule is water-loving and relatively large.

Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles.

So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging.

A 12 week human study of a multi-ingredient regimen containing this ingredient saw:

While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone).

Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations.

Acetyl Octapeptide-3 is a synthetic peptide also commonly known as SNAP-8. It is a lab-made peptide often marketed as a gentler, topical alternative to Botox.

It works by mimicking part of a protein involved in muscle contractions, which may help relax facial tension and reduce the appearance of fine lines (mostly around the eyes and forehead).

It’s considered a “next-gen” version of Argireline (Acetyl Hexapeptide-8), an older peptide with more research behind it that also supports collagen production.

SNAP-8 showed slightly better results than Argireline in one small manufacturer-funded study, but there’s limited independent research. Plus, most tests use concentrations higher than what’s typically found in skincare products.

This ingredient might offer a subtle smoothing effect but it won't don’t deliver the dramatic results of actual Botox injections.

Think of it more like a supporting actor in your skincare lineup.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Tocopherol is a fat-soluble antioxidant known as Vitamin E.

You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Side-by-side

  1. 01Water
  2. 02Propanediol
  3. 03Glycerin
  4. 04Ammonium Acryloyldimethyltaurate/Vp Copolymer
  5. 051,2-Hexanediol
  6. 06Diheptyl Succinate
  7. 07Capryloyl Glycerin/Sebacic Acid Copolymer
  8. 08Glycine
  9. 09Xanthan Gum
  10. 10Ethylhexylglycerin
  11. 11Caprylyl Glycol
  12. 12Acetyl Hexapeptide-8
  13. 13Acetyl Octapeptide-3
  14. 14Sodium Hyaluronate
  15. 15Copper Tripeptide-1
  16. 16Tocopherol
  17. 17Water, Propanediol, Glycerin, Ammonium Acryloyldimethyltaurate/Vp Copolymer, 1,2-Hexanediol, Diheptyl Succinate, Capryloyl Glycerin/Sebacic Acid Copolymer, Glycine, Xanthan Gum, Ethylhexylglycerin, Caprylyl Glycol, Acetyl Hexapeptide-8, Acetyl Octap…
  18. 18Butylene Glycol
  19. 19Squalane
  20. 20Sodium Stearoyl Glutamate
Source · skinsort.com
02

Product index

Related product references

Product

Good Molecules Super Peptide Serum

Good Molecules Super Peptide Serum Ingredients in Good Molecules Super Peptide Serum explained: benefits, concerns, and detailed analysis of 16 ingredients including Water, Propanediol, and…

Source: skinsort.comView reference →
03

Comparison edit

Read side by side