Good Skin MD Rescue Facial Cream Versus Paula's Choice RESIST Daily Smoothing Treatment With 5% AHA

Good Skin MD Rescue Facial Cream Versus Paula's Choice RESIST Daily Smoothing Treatment With 5% AHA

This acne treatment is formulated around Salicylic Acid to clear breakouts and refine skin texture.

This smoothing exfoliator is formulated around Glycolic Acid and Palmitoyl Hexapeptide-12 to refine skin texture and soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

PPG-15 Stearyl Ether

Salicylic Acid

Cetyl Alcohol

Stearyl Alcohol

Dimethicone

C13-14 Isoparaffin

Dimethiconol

Steareth-21

Laureth-7

Steareth-2

Disodium EDTA

Polyacrylamide

Water, Glycerin, PPG-15 Stearyl Ether, Salicylic Acid, Cetyl Alcohol, Stearyl Alcohol, Dimethicone, C13-14 Isoparaffin, Dimethiconol, Steareth-21, Laureth-7, Steareth-2, Disodium EDTA, Polyacrylamide

Glycolic Acid

Butylene Glycol

PPG-14 Butyl Ether

Palmitoyl Hexapeptide-12

Ceramide Ng

Tetrahydrodiferuloylmethane

Tetrahydrodemethoxydiferuloylmethane

Tetrahydrobisdemethoxydiferuloylmethane

Epigallocatechin Gallate

Disodium Lauriminodipropionate Tocopheryl Phosphates

PEG-10 Phytosterol

Vanilla Planifolia Fruit Extract

Bisabolol

Allantoin

Cyclopentasiloxane

Cyclohexasiloxane

Tribehenin

C12-15 Alkyl Benzoate

PEG-40 Stearate

Sorbitan Stearate

Pvm/Ma Decadiene Crosspolymer

Sodium Hydroxide

Caprylyl Glycol

Caprylic/Capric Triglyceride

Hexylene Glycol

Ethylhexylglycerin

Phenoxyethanol

Water, Glycolic Acid, Cetyl Alcohol, Butylene Glycol, Polyacrylamide, Dimethicone, PPG-14 Butyl Ether, Palmitoyl Hexapeptide-12, Ceramide Ng, Tetrahydrodiferuloylmethane, Tetrahydrodemethoxydiferuloylmethane, Tetrahydrobisdemethoxydiferuloylmethane, Epigallocatechin Gallate, Salicylic Acid, Disodium Lauriminodipropionate Tocopheryl Phosphates, PEG-10 Phytosterol, Vanilla Planifolia Fruit Extract, Bisabolol, Allantoin, Cyclopentasiloxane, Cyclohexasiloxane, Dimethiconol, Tribehenin, C12-15 Alkyl Benzoate, PEG-40 Stearate, Sorbitan Stearate, Pvm/Ma Decadiene Crosspolymer, Disodium EDTA, C13-14 Isoparaffin, Laureth-7, Sodium Hydroxide, Caprylyl Glycol, Caprylic/Capric Triglyceride, Hexylene Glycol, Ethylhexylglycerin, Phenoxyethanol

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

C13-14 Isoparaffin is a synthetic emollient, solvent, and thickening agent. It helps soften skin and improves spreadability without leaving a greasy residue.

This ingredient has been found to be non-sensitizing and safe for use in cosmetics.

Two things floating around online that cause fear-mongering:

There's one scary-sounding study related to kidney tumors in male rats; this depends on a protein called alpha-2u-globulin that binds the ingredient and clogs up kidney cells. Female rats barely make this protein, and humans don't make it at all so this effect cannot happen to us. Regulatory bodies have states this rat-only pathway shouldn't be used to judge human risk.

The other thing you'll see is 1,4-dioxane being a trace byproduct that can form during manufacturing of petroleum-derived ingredients. This is a real, but heavily managed/monitored issue. This byproduct is removed through purification steps before the ingredients goes into the formula. Regulatory bodies also actively monitor residual levels for safety.

One last thing to note: this ingredient is a pure hydrocarbon with no fatty-acid or ester chains for Malassezia to feed on, so it's considered fungal acne safe.

Cetyl Alcohol is a fatty alcohol. Fatty Alcohols are most often used as an emollient or to thicken a product.

Its main roles are:

Though it has "alcohol" in the name, it is not related to denatured alcohol or ethyl alcohol.

The FDA allows products labeled "alcohol-free" to have fatty alcohols.

This ingredient may not be fungal acne safe. It is a primary fatty alcohol with a chain length above 12 carbons. A study from 2019 show Malassezia can feed on fatty alcohols in this range, so it may trigger fungal acne in those prone to it.

Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.

What it does:

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

Dimethiconol is a silicone that resembles the popular dimethicone. Like other silicones, it is an emollient. Emollients create a thin film on skin to prevent moisture from escaping.

This ingredient helps to create a silky texture and improve spreadability. Due to its high molecular weight and thickness, it is often combined with cyclopentasiloxane.

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Laureth-7 is created by the ethoxylation of lauryl alcohol using ethylene oxide. Lauryl alcohol is a fatty alcohol with hydrating properties.

This ingredient is an emulsifier and cleansing ingredient. As an emulsifier, it is used to prevent ingredients from separating. It also helps cleanse the skin by gathering dirt, oil, and pollutants to be rinsed away.

Polyacrylamide is a synthetic polymer. It is used to stabilize products and bind ingredients. When hydrated, Polyacrylamide forms a soft gel.

Polyacrylamide is low-toxicity. If source properly, it is deemed safe to use in cosmetics.

It should be noted the precursor to Polyacrylamide is acrylamide. Acrylamide is a carcinogen. Most reputable sources of Polyacrylamide will screen for residual acrylamide to make sure the count is in a safe range. Acrylamide is not able to be absorbed through the skin.

We recommend speaking with a professional if you have concerns.

Salicylic Acid (also known as beta hydroxy acid or BHA) is a well-known ingredient for treating skin that struggles with acne and clogged pores. It exfoliates both the skin's surface and deep within the pores to help clear out buildup, control oil, and reduce inflammation.

Unlike AHAs (alpha hydroxy acids), salicylic acid is oil-soluble. This allows it to penetrate into pores which makes it especially effective for treating blackheads and preventing future breakouts.

Salicylic acid is also known for its soothing properties. It has a similar structure to aspirin and can calm inflamed or irritated skin, making it a good option for acne-prone skin that is also sensitive.

Concentrations of 0.5-2% are recognized by the U.S. FDA as an over-the-counter topical acne product.

It can cause irritation and/or dryness if one's skin already has a compromised moisture barrier, so it's best to focus on repairing that before introducing this ingredient into your routine.

While salicylic acid does not increase sun sensitivity, it’s still important to wear sunscreen daily to protect your skin.

If you are looking for the ingredient called BHA or Butylated Hydroxyanisole, click here.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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