Grace & Stella Hyaluronic Acid Serum Versus Drunk Elephant T.L.C. Framboos Glycolic Night Serum

Grace & Stella Hyaluronic Acid Serum Versus Drunk Elephant T.L.C. Framboos Glycolic Night Serum

This hydrating serum is formulated around Sodium Hyaluronate and Sodium Hyaluronate Crosspolymer to hydrate skin and strengthen the skin barrier.

This smoothing serum is formulated around Glycolic Acid and Lactic Acid to refine skin texture and brighten dull-looking skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Sodium Hyaluronate

Sodium Hyaluronate Crosspolymer

Panthenol

Ahnfeltia Concinna Extract

Glycerin

Pentylene Glycol

Propanediol

Polyacrylate Crosspolymer-6

Phenoxyethanol

Caprylyl Glycol

Hexylene Glycol

PPG-26-Buteth-26

PEG-40 Hydrogenated Castor Oil

Trisodium Ethylenediamine Disuccinate

Citric Acid

Ethoxydiglycol

Ethylhexylglycerin

Chlorphenesin

Hyaluronic Acid

Potassium Sorbate

Water, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Panthenol, Ahnfeltia Concinna Extract, Glycerin, Pentylene Glycol, Propanediol, Polyacrylate Crosspolymer-6, Phenoxyethanol, Caprylyl Glycol, Hexylene Glycol, PPG-26-Buteth-26, PEG-40 Hydrogenated Castor Oil, Trisodium Ethylenediamine Disuccinate, Citric Acid, Ethoxydiglycol, Ethylhexylglycerin, Chlorphenesin, Hyaluronic Acid, Potassium Sorbate

Glycolic Acid

Butylene Glycol

Sodium Hydroxide

Lactic Acid

Salicylic Acid

Tartaric Acid

Vitis Vinifera Juice Extract

Aloe Barbadensis Leaf Juice

Opuntia Ficus-Indica Extract

Aesculus Hippocastanum Seed Extract

Camellia Sinensis Leaf Extract

Rubus Idaeus Fruit Extract

Saccharomyces Cerevisiae Extract

Buddleja Davidii Meristem Cell Culture

Sclerocarya Birrea Seed Oil

Allantoin

Hydroxyethylcellulose

Galactoarabinan

Tetrasodium Glutamate Diacetate

Xanthan Gum

Sodium Benzoate

Sodium Carbonate

Sodium Chloride

Disodium Phosphate

Sodium Phosphate

Water, Glycolic Acid, Butylene Glycol, Glycerin, Sodium Hydroxide, Lactic Acid, Salicylic Acid, Tartaric Acid, Vitis Vinifera Juice Extract, Aloe Barbadensis Leaf Juice, Opuntia Ficus-Indica Extract, Aesculus Hippocastanum Seed Extract, Camellia Sinensis Leaf Extract, Rubus Idaeus Fruit Extract, Saccharomyces Cerevisiae Extract, Buddleja Davidii Meristem Cell Culture, Sclerocarya Birrea Seed Oil, Sodium Hyaluronate Crosspolymer, Allantoin, Hydroxyethylcellulose, Galactoarabinan, Propanediol, Citric Acid, Tetrasodium Glutamate Diacetate, Xanthan Gum, Hexylene Glycol, Phenoxyethanol, Sodium Benzoate, Caprylyl Glycol, Potassium Sorbate, Pentylene Glycol, Sodium Carbonate, Sodium Chloride, Disodium Phosphate, Sodium Phosphate, Ethylhexylglycerin

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.

Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.

However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.

Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.

In skincare formulas, citric acid can:

While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.

Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.

Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.

However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is unique, we recommend a patch test if you are unsure.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Hexylene Glycol is a multitasker ingredient that works as a solvent, humectant, emulsifier, viscosity reducer, and preservative booster.

It is able to dissolve both water and oil-soluble ingredients to stabilize tricky actives and make products spread more easily.

As a humectant, it pulls water into the skin. But it's a pretty minor moisturizing ingredient compared to other humectants, like glycerin.

Interestingly, it can act as a mild penetration enhancer. One in vitro study on human skin found a 12% concentration upped the absorption of mometasone furoate (a medicinal ingredient used to treat inflammatory skin conditions) up to 7%.

This ingredient is typically used at levels of 0.1-10% depending on the role it's playing.

A patch test study on eczema patients didn't find a significant increase in irritation versus the control group, but the potential for irritation rises at higher concentrations.

Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:

Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.

On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.

Typical use levels in a formula run about 1-5%.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.

This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.

Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.

You'll often find this ingredient used with other preservatives.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Sodium Hyaluronate Crosspolymer is a crosslinked version of sodium hyaluronate. This just means it's linked into a 3D mesh network that lets it be more stable and sit on skin as a cohesive, gel-like film rather than sinking into skin.

A 2016 human skin study found crosslinked HA increased epidermal water content by 7.6% over the control group and reduced transepidermal water loss by 27.8%.

A follow-up clinical trial found that a topical crosslinked HA serum applied after fillers, microneedling, or chemical peels was well-tolerated and enhanced skin quality at 14 / 28 days.

More recent research suggests that concentrations as low as 0.03% can act as a penetration enhancer for other skincare actives.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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