Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Handmade Heroes The Ultimate Snow Shroom HA Serum Versus Isntree Ultra-Low Molecular Hyaluronic Acid Serum

Handmade Heroes The Ultimate Snow Shroom HA Serum Versus Isntree Ultra-Low Molecular Hyaluronic Acid Serum This hydrating serum is formulated around Sodium Hyaluronate and Hydrolyzed Sodium Hyaluronate to hydrate skin and calm redness. This hydrating serum is

Handmade Heroes The Ultimate Snow Shroom HA Serum Versus Isntree Ultra-Low Molecular Hyaluronic Acid Serum

This hydrating serum is formulated around Sodium Hyaluronate and Hydrolyzed Sodium Hyaluronate to hydrate skin and calm redness.

This hydrating serum is formulated around Panthenol and Hydrolyzed Hyaluronic Acid to hydrate skin and strengthen the skin barrier.

What's inside

Key Ingredients

Benefits

Ingredients Side-by-side

Water

Propanediol

Pentylene Glycol

Glycerin

Lonicera Caprifolium Flower Extract

Sodium Hyaluronate

Hydrolyzed Sodium Hyaluronate

Lonicera Japonica Flower Extract

Tremella Fuciformis Polysaccharide

Tamarindus Indica Seed Gum

Sodium Phytate

Sodium Bicarbonate

Melia Azadirachta Leaf Extract

Melia Azadirachta Flower Extract

Corallina Officinalis Extract

Coccinia Indica Fruit Extract

Solanum Melongena Fruit Extract

Aloe Barbadensis Flower Extract

Ocimum Sanctum Leaf Extract

Ocimum Basilicum Flower/Leaf Extract

Curcuma Longa Root Extract

Water, Propanediol, Pentylene Glycol, Glycerin, Lonicera Caprifolium Flower Extract, Sodium Hyaluronate, Hydrolyzed Sodium Hyaluronate, Lonicera Japonica Flower Extract, Tremella Fuciformis Polysaccharide, Tamarindus Indica Seed Gum, Sodium Phytate, Sodium Bicarbonate, Melia Azadirachta Leaf Extract, Melia Azadirachta Flower Extract, Corallina Officinalis Extract, Coccinia Indica Fruit Extract, Solanum Melongena Fruit Extract, Aloe Barbadensis Flower Extract, Ocimum Sanctum Leaf Extract, Ocimum Basilicum Flower/Leaf Extract, Curcuma Longa Root Extract

Sea Water

Methylpropanediol

Butylene Glycol

1,2-Hexanediol

Betaine

Carbomer

Caprylyl Glycol

Allantoin

Tromethamine

Ethylhexylglycerin

Xanthan Gum

Panthenol

Malachite Extract

Hydrolyzed Hyaluronic Acid

Disodium EDTA

Glyceryl Acrylate/Acrylic Acid Copolymer

Glyceryl Glucoside

Potassium Hyaluronate

Hyaluronic Acid

Sodium Acetylated Hyaluronate

Hydroxypropyltrimonium Hyaluronate

Sodium Hyaluronate Crosspolymer

Dimethylsilanol Hyaluronate

Hydrolyzed Calcium Hyaluronate

Sodium Sulfated Hyaluronate

Madecassoside

Beta-Glucan

Sodium Stearoyl Hyaluronate

Sodium Oleoyl Hyaluronate

Sea Water, Water, Methylpropanediol, Glycerin, Butylene Glycol, 1,2-Hexanediol, Betaine, Pentylene Glycol, Carbomer, Caprylyl Glycol, Allantoin, Tromethamine, Ethylhexylglycerin, Xanthan Gum, Panthenol, Malachite Extract, Hydrolyzed Hyaluronic Acid, Disodium EDTA, Glyceryl Acrylate/Acrylic Acid Copolymer, Glyceryl Glucoside, Sodium Hyaluronate, Potassium Hyaluronate, Hyaluronic Acid, Hydrolyzed Sodium Hyaluronate, Sodium Acetylated Hyaluronate, Hydroxypropyltrimonium Hyaluronate, Sodium Hyaluronate Crosspolymer, Dimethylsilanol Hyaluronate, Hydrolyzed Calcium Hyaluronate, Sodium Sulfated Hyaluronate, Madecassoside, Beta-Glucan, Sodium Stearoyl Hyaluronate, Sodium Oleoyl Hyaluronate

Reviews

Be the first to review

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

This ingredient is created by putting sodium hyaluronate through hydrolysis.

You might know this as 'mini' or 'ultra low-molecular weight' hyaluronic acid. The small molecule size means it is able to travel deeper in the skin.

According to studies, low molecular-weight hyaluronic acid can:

One study from 2011 found ultra-low weight HA to show pro-inflammatory properties. Another study from 2022 found it to downregulate UV-B induced inflammation.

Hydrolysis is a process of changing a molecule using water or enzymes.

This ingredient is water-soluble.

Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:

Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.

On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.

Typical use levels in a formula run about 1-5%.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Side-by-side

  1. 01Water
  2. 02Propanediol
  3. 03Sodium Hyaluronate
  4. 04PEG-40 Hydrogenated Castor Oil
  5. 05Glycerin
  6. 06Hydroxyacetophenone
  7. 07Caprylyl Glycol
  8. 08Phenethyl Alcohol
  9. 09Saccharide Isomerate
  10. 10Allantoin
  11. 11Disodium EDTA
  12. 12Vitis Vinifera Seed Extract
  13. 13Hippophae Rhamnoides Fruit Oil
  14. 14Lactic Acid
  15. 15Hydrolyzed Sodium Hyaluronate
  16. 16Ceramide NP
  17. 17Ceramide AP
  18. 18Ceramide EOP
  19. 19Phytosphingosine
  20. 20Cholesterol
Source · skinsort.com
02

Product index

Related product references

Product

Dermoten Hyaluronic Acid Serum

Dermoten Hyaluronic Acid Serum Ingredients in Dermoten Hyaluronic Acid Serum explained: benefits, concerns, and detailed analysis of 15 ingredients including Water, Propylene Glycol, and Ph…

Source: skinsort.comView reference →

Product

Skin Generics Hyaluronic Acid Serum

Skin Generics Hyaluronic Acid Serum Skin Generics Hyaluronic Acid Serum ingredients explained: Aqua (Water), Aloe Barbadensis (Vera) Leaf Extract, Glycerin, Propanediol, Phenoxyethanol, Cel…

Source: incidecoder.comView reference →
03

Comparison edit

Read side by side

04

Ask the journal

Related questions

01When and How to Use Hyaluronic Acid in Your Routine

Products with hyaluronic acid can be used in the morning or at night (or both!). Applying the hydrating ingredient at night will restore your skin’s resilience while you sleep, and applying it in the morning will leave your skin feeling plump, hydrated and ready for makeup. Hyaluronic acid is great at providing topical hydration when it’s introduced into a balanced skincare routine. According to Dr. King, it’s important to pair your hyaluronic acid products with an emollient or occlusive moisturizer to lock in hydration.

Source · www.skincare.com
02How to Apply Face Serums

Skincare rules can get confusing, but when it comes to application the general rule of thumb is to pay attention to the product’s consistency. “Apply the lightest, thinnest product first and the heaviest, and more dense products last, since thinner products can’t penetrate thicker products,”says Dr. Lewis. After cleansing the face and following up with a toner, let the skin dry before using a serum. You can layer different serums on top of each other or opt for a product that has a precise mix of multiple hero ingredients, such as hyaluronic acid and vitamin C.

Source · www.skincare.com