Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Haruharu Wonder Centella Phyto & 5 Peptide Concentrate Cream Versus Dieux Skin Instant Angel

Haruharu Wonder Centella Phyto & 5 Peptide Concentrate Cream Versus Dieux Skin Instant Angel This anti-aging moisturizer is formulated around Centella Asiatica Extract and Madecassoside to soften the look of wrinkles and calm redness. This barrier-repair moist

Haruharu Wonder Centella Phyto & 5 Peptide Concentrate Cream Versus Dieux Skin Instant Angel

This anti-aging moisturizer is formulated around Centella Asiatica Extract and Madecassoside to soften the look of wrinkles and calm redness.

This barrier-repair moisturizer is formulated around Squalane and Linoleic Acid to strengthen the skin barrier and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Butylene Glycol

Caprylic/Capric Triglyceride

Helianthus Annuus Seed Oil

Polyglyceryl-3 Distearate

1,2-Hexanediol

Cetyl Alcohol

Cetyl Palmitate

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Sorbitan Palmitate

Sorbitan Olivate

Glyceryl Stearate

Stearyl Alcohol

Xanthan Gum

Glyceryl Stearate Citrate

Myristyl Alcohol

Squalane

Caffeine

Hydrolyzed Soy Protein

Hydrogenated Lecithin

Pentylene Glycol

Ethylhexylglycerin

Adenosine

Butyrospermum Parkii Butter

Phytosterols

Lauryl Alcohol

Centella Asiatica Extract

Hydrolyzed Pea Protein

Madecassoside

Asiaticoside

Caprylyl Glycol

Xylitylglucoside

Anhydroxylitol

Copper Tripeptide-1

Xylitol

Acetyl Hexapeptide-8

Asiatic Acid

Madecassic Acid

Glucose

Ceramide NP

Hippophae Rhamnoides Fruit Extract

Oligopeptide-32

Oligopeptide-29

Palmitoyl Pentapeptide-4

Water, Glycerin, Butylene Glycol, Caprylic/Capric Triglyceride, Helianthus Annuus Seed Oil, Polyglyceryl-3 Distearate, 1,2-Hexanediol, Cetyl Alcohol, Cetyl Palmitate, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Sorbitan Palmitate, Sorbitan Olivate, Glyceryl Stearate, Stearyl Alcohol, Xanthan Gum, Glyceryl Stearate Citrate, Myristyl Alcohol, Squalane, Caffeine, Hydrolyzed Soy Protein, Hydrogenated Lecithin, Pentylene Glycol, Ethylhexylglycerin, Adenosine, Butyrospermum Parkii Butter, Phytosterols, Lauryl Alcohol, Centella Asiatica Extract, Hydrolyzed Pea Protein, Madecassoside, Asiaticoside, Caprylyl Glycol, Xylitylglucoside, Anhydroxylitol, Copper Tripeptide-1, Xylitol, Acetyl Hexapeptide-8, Asiatic Acid, Madecassic Acid, Glucose, Ceramide NP, Hippophae Rhamnoides Fruit Extract, Oligopeptide-32, Oligopeptide-29, Palmitoyl Pentapeptide-4

Coconut Alkanes

Meadowfoam Estolide

PEG-100 Stearate

Cetearyl Alcohol

C12-15 Alkyl Benzoate

Phytosteryl Macadamiate

Triheptanoin

Coco-Caprylate/Caprate

Methylpropanediol

Linoleic Acid

Phospholipids

Sodium Polyacrylate

Tribehenin

Phenoxyethanol

Dipalmitoyl Hydroxyproline

Sodium PCA

Urea

Dilinoleic Acid/Butanediol Copolymer

Hydroxyproline Palmitamide

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Isohexadecane

Ceramide Ng

Trehalose

Sodium Phytate

PEG-10 Phytosterol

Hexylene Glycol

Polysorbate 60

Palmitic Acid

Lactic Acid

Polyquaternium-51

Tocopherol

Triacetin

Castor Oil/Ipdi Copolymer

Sorbitan Isostearate

Sodium Hyaluronate

Palmitoyl Hexapeptide-12

Water, Glycerin, Squalane, Caprylic/Capric Triglyceride, Coconut Alkanes, Glyceryl Stearate, Meadowfoam Estolide, PEG-100 Stearate, Cetearyl Alcohol, C12-15 Alkyl Benzoate, Phytosteryl Macadamiate, Triheptanoin, Coco-Caprylate/Caprate, Methylpropanediol, Linoleic Acid, Phospholipids, Phytosterols, Sodium Polyacrylate, Tribehenin, Caprylyl Glycol, Phenoxyethanol, Dipalmitoyl Hydroxyproline, Sodium PCA, Urea, Dilinoleic Acid/Butanediol Copolymer, Hydroxyproline Palmitamide, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Isohexadecane, Ceramide Ng, Trehalose, Sodium Phytate, PEG-10 Phytosterol, Hexylene Glycol, Polysorbate 60, Palmitic Acid, Lactic Acid, Polyquaternium-51, Tocopherol, Triacetin, Castor Oil/Ipdi Copolymer, Sorbitan Isostearate, Sodium Hyaluronate, Palmitoyl Hexapeptide-12

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.

Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.

In practice, that translates to a long shelf life and a consistently elegant skin feel.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.

Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.

This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.

This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Glyceryl Stearate is made by reacting glycerin with stearic acid (typically sourced from plant oils like palm or coconut). It's an emulsifier, emollient, and mild occlusive.

Emulsifiers help ingredients like oil and water stay mixed so your formula stays nicely blended and uniform in texture.

This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototoxic, and non-photoallergenic.

A close cousin of this ingredient is Glyceryl Stearate SE ("self-emulsifying"). This just has a small amount of sodium or potassium stearate added so it can emulsify without a co-emulsifier.

Since this ingredient is an ester of a C18 fatty acid, it may not be fungal acne safe. The Malassezia yeast can potentially metabolize within the C11-C24 range.

Fun fact: The human body also creates Glyceryl Stearate naturally.

Phytosterols are plant-derived sterols (you can think of them as the plant world's version of cholesterol). In cosmetics, this ingredient is usually sourced from soybean, rice bran, shea, sunflower, and other seed oils.

The main actors in this group are β-sitosterol, campesterol, and stigmasterol (the CIR covers 27 phytosterols).

They work by fitting perfectly into your stratum corneum's lipid matrix since they're structurally similar to cholesterol. Here, they reinforce your skin's barrier.

One small in vivo human study showed topical soybean phytosterols sped up barrier recovery within three days on tape-stripped skin.

Broader research credits them with:

Formulation use typically sit under 5%.

Testing in soy-allergic subjects found no sensitization signals, but be sure to patch test if you are unsure or have existing allergies.

Squalane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).

It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.

This is due to how structurally similar it is to what your skin already produces.

Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.

Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.

No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).

Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.

The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.

Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.

A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.

The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Side-by-side

  1. 01Water
  2. 02Glycerin
  3. 03Butylene Glycol
  4. 04Caprylic/Capric Triglyceride
  5. 05Helianthus Annuus Seed Oil
  6. 06Polyglyceryl-3 Distearate
  7. 071,2-Hexanediol
  8. 08Cetyl Alcohol
  9. 09Cetyl Palmitate
  10. 10Ammonium Acryloyldimethyltaurate/Vp Copolymer
  11. 11Sorbitan Palmitate
  12. 12Sorbitan Olivate
  13. 13Glyceryl Stearate
  14. 14Stearyl Alcohol
  15. 15Xanthan Gum
  16. 16Glyceryl Stearate Citrate
  17. 17Myristyl Alcohol
  18. 18Squalane
  19. 19Caffeine
  20. 20Hydrolyzed Soy Protein
Source · skinsort.com
02

Product index

Related product references

03

Comparison edit

Read side by side