Haruharu Wonder Rose PDRN Peptide Glowy Balm Versus Anua PDRN Lip Serum

Haruharu Wonder Rose PDRN Peptide Glowy Balm Versus Anua PDRN Lip Serum

This anti-aging lip moisturizer is formulated around Butyrospermum Parkii Butter and Sodium DNA to soften the look of wrinkles and hydrate lips.

This anti-aging lip moisturizer is formulated around Sodium DNA and Ceramide NP to soften the look of wrinkles and hydrate lips.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Polyglyceryl-2 Isostearate/Dimer Dilinoleate Copolymer

Polyglyceryl-2 Triisostearate

Diisostearyl Malate

Phytosteryl/Isostearyl/Cetyl/Stearyl/Behenyl Dimer Dilinoleate

Bis-Diglyceryl Polyacyladipate-2

Polyglyceryl-10 Decaisostearate

Tridecyl Trimellitate

Butyrospermum Parkii Butter

Octyldodecanol

Euphorbia Cerifera Wax

Synthetic Wax

Silica Dimethyl Silylate

Glyceryl Behenate/Eicosadioate

Tocopheryl Acetate

Polyglyceryl-6 Polyricinoleate

Sorbitan Sesquioleate

Ethylene/Propylene Copolymer

Microcrystalline Wax

Dehydroacetic Acid

Water

Ceramide NP

Tocopherol

Panthenol

Simmondsia Chinensis Seed Oil

Lactic Acid

Butylene Glycol

1,2-Hexanediol

Glycerin

Caprylyl Glycol

Ethylhexylglycerin

Sodium DNA

Tripeptide-1

Acetyl Hexapeptide-8

Copper Tripeptide-1

Palmitoyl Pentapeptide-4

Hexapeptide-9

Polyglyceryl-2 Isostearate/Dimer Dilinoleate Copolymer, Polyglyceryl-2 Triisostearate, Diisostearyl Malate, Phytosteryl/Isostearyl/Cetyl/Stearyl/Behenyl Dimer Dilinoleate, Bis-Diglyceryl Polyacyladipate-2, Polyglyceryl-10 Decaisostearate, Tridecyl Trimellitate, Butyrospermum Parkii Butter, Octyldodecanol, Euphorbia Cerifera Wax, Synthetic Wax, Silica Dimethyl Silylate, Glyceryl Behenate/Eicosadioate, Tocopheryl Acetate, Polyglyceryl-6 Polyricinoleate, Sorbitan Sesquioleate, Ethylene/Propylene Copolymer, Microcrystalline Wax, Dehydroacetic Acid, Water, Ceramide NP, Tocopherol, Panthenol, Simmondsia Chinensis Seed Oil, Lactic Acid, Butylene Glycol, 1,2-Hexanediol, Glycerin, Caprylyl Glycol, Ethylhexylglycerin, Sodium DNA, Tripeptide-1, Acetyl Hexapeptide-8, Copper Tripeptide-1, Palmitoyl Pentapeptide-4, Hexapeptide-9

Polyisobutene

Dipentaerythrityl Hexahydroxystearate/Hexastearate/Hexarosinate

Polyglyceryl-3 Polyricinoleate

Dextrin Palmitate

Pentylene Glycol

Dimethicone

Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate

Caprylic/Capric Triglyceride

Stearalkonium Hectorite

Polyglyceryl-3 Diisostearate

Rosa Damascena Flower Extract

Disodium EDTA

Hydrogenated Lecithin

Hyaluronic Acid

Hydrolyzed Collagen

Polyisobutene, Diisostearyl Malate, Polyglyceryl-2 Triisostearate, Dipentaerythrityl Hexahydroxystearate/Hexastearate/Hexarosinate, Octyldodecanol, Microcrystalline Wax, Bis-Diglyceryl Polyacyladipate-2, Phytosteryl/Isostearyl/Cetyl/Stearyl/Behenyl Dimer Dilinoleate, Polyglyceryl-3 Polyricinoleate, 1,2-Hexanediol, Dextrin Palmitate, Silica Dimethyl Silylate, Simmondsia Chinensis Seed Oil, Water, Synthetic Wax, Pentylene Glycol, Ethylene/Propylene Copolymer, Butylene Glycol, Caprylyl Glycol, Dimethicone, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Caprylic/Capric Triglyceride, Ethylhexylglycerin, Stearalkonium Hectorite, Polyglyceryl-3 Diisostearate, Rosa Damascena Flower Extract, Sodium DNA, Disodium EDTA, Panthenol, Glycerin, Ceramide NP, Hydrogenated Lecithin, Hyaluronic Acid, Hydrolyzed Collagen

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Bis-Diglyceryl Polyacyladipate-2 is a synthetic emollient that works as a lanolin substitute.

This ingredient is a great vegan option for those avoiding animal-derived ingredients.

It mostly stays on the surface of skin where it helps hydrate due to its large molecular size and low water solubility.

Due to it being derived from fatty acids, this ingredient may not be Malassezia or fungal acne safe.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.

Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.

This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.

A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.

Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.

Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.

Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.

Diisostearyl Malate is an emollient and most often used in lip products. It comes from isostearyl alcohol, a fatty acid, and malic acid, an AHA.

As an emollient, Diisostearyl Malate helps create a thin film on your skin to trap moisture in. This helps keep your skin soft and smooth.

Ethylene/Propylene Copolymer is an exfoliant.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Microcrystalline Wax is derived from petroleum through a de-oiling process, then highly refined and purified before use in cosmetics.

In skincare formulations, it is used to improve texture and create a smooth, even consistency. It also helps stabilize products by preventing ingredients from separating.

Octyldodecanol is a fatty alcohol sourced from plant oils like coconut or palm (or made synthetically).

It is:

You'll likely see this in many BHA products because this is the go-to solvent for salicylic acid.

This ingredient is typically used at levels between 2-20%.

Regarding fungal acne: In 2019, this ingredient was tested against multiple Malassezia species (the yeast that causes fungal acne) and showed no growth.

Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.

There are two forms of panthenol: D and L.

D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.

Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):

Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.

This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.

Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.

This ingredient is also referred to as pro-vitamin B5.

This is a plant-derived ester that functions as a skin conditioner. It's basically a two linoleic acid molecules combined with fatty alcohols.

In practice, it works as a rich emollient that helps reduce moisture loss and give skin a soft appearance.

The phytosterol part of this ingredient brings an added structural bonus: phytosterols are structurally similar to cholesterol so they can fit right into the stratum corneum's lipid matrix to help reinforce the skin barrier.

Due to its molecular structure, this ingredient delivers a cushiony and glossy feeling without being excessively greasy.

It did not produce skin irritation or sensitization in clinical studies, and this ingredient is deemed safe to use in cosmetics at current practices.

Because this ingredient contains C16, C18, and C22 fatty chains, it may not be Malassezia/fungal acne safe. The Malassezia yeast potentially feeds on fatty acids in the C11-C24 range.

Polyglyceryl-2 Triisostearate is a plant-derived emulsifier and pigment-dispersing agent with a non-sticky skin feel.

It helps products glide on smoothly and prevents oil and water from separating in a formula, making it suitable for sunscreen and makeup formulations.

The EU inventory of cosmetics has no use restrictions on this ingredient and it is considered well-tolerated.

This ingredient may not be fungal acne safe because it is derived from isostearic acid.

This silica is mainly used to thicken oils and suspend particles in oils. It is not water soluble.

According to the manufacturer, it:

The manufacturer also claims this ingredient to be useful in makeup.

In lipstick formulations, this ingredient improves color payoff, reduces pigment settling, and reduces oil bleeding. This ingredient also improves the grip of powder products such as dry shampoos.

Jojoba oil is one of the most well-studied plant-derived ingredients in cosmetics. It is an emollient with a special structure.

Because it is made up of 97-98% wax esters, it closely mirrors the linear monoesters found in human sebum. This makes it skin compatible, non-greasy, and lightweight.

Unlike other plant oils, jojoba wax doesn't easily penetrate skin. It mostly works in the uppermost layers as an emollient. This just means it forms a light barrier on the skin to help retain moisture.

Formulations with jojoba esters up to 90% reduced transepidermal water loss (TEWL) and increased barrier recovery by 81% (outperforming bisabolol at 47%).

Besides barrier support, the science also suggests jojoba to have anti-inflammatory effects and potential applications for skin infections, aging, and wound healing.

Fun fact: Indigenous cultures have used jojoba as a moisturizer and to help treat burns for centuries.

Fungal acne: The Malassezia yeast is known to metabolize fatty acids in the C11-24 range and jojoba's dominant fatty acid components fall into this range. This ingredient may not be fungal acne safe.

Sodium DNA is an emerging anti-aging ingredient.

It is created by taking deoxyribonucleic acid (DNA) and purifying it with sodium hydroxide.

The DNA is extracted from several different animal sources, including: calf thymus, the gonadic tissue of a male sturgeon, or herring / salmon sperm.

You have probably seen this ingredient in anti-aging skincare. But what is it?

DNA is composed of nucleotides, or chemical building blocks. Nucleotides include adenine (A), thymine (T), guanine (G), and cytosine (C). Talk about a flashback to biology! Nucleosides are formed from these nucleotides.

The science behind Sodium DNA is based on an ingredient called Polydeoxyribonucleotide or PDRN.

PDRN are DNA fragments mainly extracted from the sperm cells of trout or salmon. Meaning, PDRN can be derived from Sodium DNA.

PDRN consists of chains of nucleotides and nucleosides mentioned above. They can range anywhere from 80 - 2000 pairs.

Studies show PDRN has the following properties:

Most of the research on PDRN has been done using injectable forms. That’s important, because PDRN is a large molecule and doesn’t absorb well through the skin. So if you’re applying it topically, the effects are likely to be much milder.

Still, topical Sodium DNA is emerging as a trendy anti-aging ingredient. It’s generally well-tolerated and offers good biocompatibility with human skin, making it a low-risk addition to most routines.

Further studies are needed to truly confirm this ingredients anti-aging ability (Remember, retinol has decades of research!).

Sodium DNA may be sourced from fish, animal tissue, or plants. Since this isn’t always disclosed, we recommend asking the brand directly if the ingredient’s origin is important to you.

Synthetic Wax is a manufactured hydrocarbon wax. In formulas, it works as an occlusive emollient that helps reduce water loss and improves the spreadability of products.

Research comparing synthetic wax to traditional mineral-derived products found that formulas containing it perform as well for skin hydration.

It is considered non-comedogenic and vegan-friendly.

This ingredient has a well-established safety record by the CIR Expert Panel for Cosmetic Ingredient Safety.

Synthetic Waxes are straight/branched-chain hydrocarbons with no ester bond or fatty acids. That means there is nothing for the Malassezia yeast to feed on.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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