Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

IMAGE skincare Clear Cell Medicated Acne Lotion Versus Sandoz Adapalene/Benzoyl Peroxide Topical Gel

IMAGE skincare Clear Cell Medicated Acne Lotion Versus Sandoz Adapalene/Benzoyl Peroxide Topical Gel This acne moisturizer is formulated around Benzoyl Peroxide and Melaleuca Alternifolia Leaf Oil to clear breakouts and balance excess oil. This acne treatment

IMAGE skincare Clear Cell Medicated Acne Lotion Versus Sandoz Adapalene/Benzoyl Peroxide Topical Gel

This acne moisturizer is formulated around Benzoyl Peroxide and Melaleuca Alternifolia Leaf Oil to clear breakouts and balance excess oil.

This acne treatment is formulated around Adapalene and Benzoyl Peroxide to clear breakouts and refine skin texture.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Benzoyl Peroxide 5%

Water

Caprylic/Capric Triglyceride

Oligopeptide-10

Cetearyl Olivate

Syringa Vulgaris Extract

Chamomilla Recutita Flower Extract

Oryza Sativa Bran Extract

Sorbitan Olivate

Aloe Barbadensis Leaf Extract

Stearic Acid

Sucrose Cocoate

Tocopheryl Acetate

Maltodextrin

Melaleuca Alternifolia Leaf Oil

Mentha Viridis Leaf Oil

Disodium EDTA

Eucalyptus Globulus Leaf Oil

Arnica Montana Flower Extract

Aesculus Hippocastanum Extract

Melia Azadirachta Leaf Extract

Boswellia Serrata Extract

Honey Extract

Camellia Sinensis Leaf Extract

Potassium Sorbate

Sodium Benzoate

Butylene Glycol

Phenoxyethanol

Caprylyl Glycol

Hexylene Glycol

Benzoyl Peroxide 5%, Water, Caprylic/Capric Triglyceride, Oligopeptide-10, Cetearyl Olivate, Syringa Vulgaris Extract, Chamomilla Recutita Flower Extract, Oryza Sativa Bran Extract, Sorbitan Olivate, Aloe Barbadensis Leaf Extract, Stearic Acid, Sucrose Cocoate, Tocopheryl Acetate, Maltodextrin, Melaleuca Alternifolia Leaf Oil, Mentha Viridis Leaf Oil, Disodium EDTA, Eucalyptus Globulus Leaf Oil, Arnica Montana Flower Extract, Aesculus Hippocastanum Extract, Melia Azadirachta Leaf Extract, Boswellia Serrata Extract, Honey Extract, Camellia Sinensis Leaf Extract, Potassium Sorbate, Sodium Benzoate, Butylene Glycol, Phenoxyethanol, Caprylyl Glycol, Hexylene Glycol

Adapalene 0.1%

Benzoyl Peroxide 2.5%

Acrylamide/Sodium Acryloyldimethyltaurate Copolymer

Sodium Anisate

Glycerin

Isohexadecane

Poloxamer 124

Polysorbate 80

Propylene Glycol

Sorbitan Oleate

Adapalene 0.1%, Benzoyl Peroxide 2.5%, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Sodium Anisate, Disodium EDTA, Glycerin, Isohexadecane, Poloxamer 124, Polysorbate 80, Propylene Glycol, Sorbitan Oleate, Water

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Benzoyl Peroxide (BPO) is one of the most studied and widely used acne-fighting ingredients on the market for over five decades.

It works by releasing oxygen into your pores to kill Cutibacterium acne, or the bacteria closely linked to acne breakouts. This bacteria has a hard time surviving in an oxygen-rich environment.

On top of that, BPO has keratolytic properties to help shed dead skin cells and keep pores from getting clogged.

One of the coolest things about BPO is that bacteria do not develop resistance to it the way they can with antibiotics. That's why dermatologists recommend pairing it with topical antibiotics to keep resistance at bay.

BPO is usually available in 2.5%, 5%, and 10% concentrations. Research has shown that 2.5% tends to be just as effective as the higher strengths while being more gentle on the skin.

The FDA has classified BPO as a safe and effective acne treatment. You'll be able to find this ingredient in over-the-counter products in many countries.

Just so you know, BPO is a known mild irritant. It's common to see dryness, peeling, and some redness when you first start using it. This usually goes away as your skin adjusts.

A very small number of people might develop allergic contact dermatitis from it as patch test studies show positive reactions in about 1-5% of patients.

Once BPO is absorbed into the skin, our bodies turn it into benzoic acid and quickly exits in urine. It's also worth noting that BPO will bleach fabrics and hair, so watch your towels and pillowcases!

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
  2. 02So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
  3. 03You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
  4. 04Glycolic Acid is arguably the most famous alpha hydroxy acid (AHA) with tons of research backing its benefits.
  5. 05It is found naturally in sugar cane but the form used in skincare is usually synthetic for purity and stability.
  6. 06Glycolic acid removes the top layer of dead skin cells to allow newer and fresher ones to emerge.
  7. 07AHAs work by breaking down the structural “glue” that holds old skin cells in place. When that buildup is gone, your skin can renew itself more efficiently.
  8. 08Research also shows glycolic acid stimulates collagen production, helping to firm and thicken the skin over time. This is one of its biggest advantages over other AHAs.
  9. 09Overall, glycolic acid helps with:
  10. 10Fun fact: Glycolic acid boosts skin hydration by helping it produce molecules that increase hyaluronic acid naturally.
  11. 11To work best, glycolic acid products should have a pH between 3-4 (that’s where exfoliation is most effective but still gentle on skin).
  12. 12The pH and concentration of a product are key to its effectiveness:
  13. 13It is normal to feel a slight stinging sensation when using glycolic acid. This usually fades as your skin adjusts.
  14. 14Because glycolic acid has the smallest molecular size in the AHA family, it can penetrate deeper, which enhances its effectiveness but also makes it more likely to irritate sensitive skin.
  15. 15If your skin is very sensitive or prone to rosacea, glycolic acid may be too strong; in that case, try milder options like lactic acid or a PHA instead.
  16. 16Recent studies suggest glycolic acid might even help protect against UV damage. But don’t skip sunscreen! Freshly exfoliated skin is more sensitive to the sun.
  17. 17Glycolic acid is a skincare superstar. It smooths, brightens, hydrates, and firms the skin. Unless you’re highly sensitive, it’s well worth adding to your routine.
  18. 18Read more about some other popular AHA's here:
  19. 19Ammonium Laureth Sulfate is a type of sulfate.
  20. 20Ammonium Lauryl Sulfate is a type of sulfate. It can be bad for dry skin, cause irritation, and worsen rosacea.
Source · skinsort.com
02

Product index

Related product references

03

Comparison edit

Read side by side