In Your Face Bio Peptide EGF6 Firming Serum Versus Platinum Skincare Regenerate Cellular Growth

In Your Face Bio Peptide EGF6 Firming Serum Versus Platinum Skincare Regenerate Cellular Growth

This anti-aging serum is formulated around Aloe Barbadensis Leaf Juice and Sh-Oligopeptide-1 to soften the look of wrinkles and hydrate skin.

This anti-aging serum is formulated around Sh-Oligopeptide-1 and Panthenol to soften the look of wrinkles and strengthen the skin barrier.

What's inside

Key Ingredients

Benefits

Concerns

No concerns

Ingredients Side-by-side

Aloe Barbadensis Leaf Juice

Rosa Damascena Flower Water

Squalane

Pentylene Glycol

Water

Lecithin

Acetyl Glutamine

Propanediol

Sh-Oligopeptide-1

Sh-Oligopeptide-2

Sh-Polypeptide-1

Sh-Polypeptide-9

Sh-Polypeptide-11

Bacillus/Folic Acid Ferment Filtrate Extract

Sodium Hyaluronate

Copper Tripeptide-1

Glycerin

Olea Europaea Fruit Oil

Sesamum Indicum Seed Oil

Arginine

Camellia Sinensis Leaf Extract

Sphingomonas Ferment Extract

Hydrolyzed Gardenia Florida Extract

Maltodextrin

1,2-Hexanediol

Caprylyl Glycol

Polyglyceryl-4 Caprate

Ethylhexylglycerin

Boswellia Serrata Oil

Anthemis Nobilis Flower Oil

Aloe Barbadensis Leaf Juice, Rosa Damascena Flower Water, Squalane, Pentylene Glycol, Water, Lecithin, Acetyl Glutamine, Propanediol, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-9, Sh-Polypeptide-11, Bacillus/Folic Acid Ferment Filtrate Extract, Sodium Hyaluronate, Copper Tripeptide-1, Glycerin, Olea Europaea Fruit Oil, Sesamum Indicum Seed Oil, Arginine, Camellia Sinensis Leaf Extract, Sphingomonas Ferment Extract, Hydrolyzed Gardenia Florida Extract, Maltodextrin, 1,2-Hexanediol, Caprylyl Glycol, Polyglyceryl-4 Caprate, Ethylhexylglycerin, Boswellia Serrata Oil, Anthemis Nobilis Flower Oil

Ethoxydiglycol

Epidermal Stem Cell Culture Extract

Soluble Collagen

Panthenol

Sodium PCA

Xanthan Gum

Malus Domestica Fruit Cell Culture Extract

Hydrolyzed Elastin

Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate

Magnesium Chloride

Hydrolyzed Hyaluronic Acid

Phenoxyethanol

Water, Glycerin, Ethoxydiglycol, Propanediol, Epidermal Stem Cell Culture Extract, Soluble Collagen, Panthenol, Sodium PCA, Lecithin, Xanthan Gum, Malus Domestica Fruit Cell Culture Extract, Hydrolyzed Elastin, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Acetyl Glutamine, Magnesium Chloride, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-9, Sh-Polypeptide-11, Bacillus/Folic Acid Ferment Filtrate Extract, Caprylyl Glycol, Phenoxyethanol, Ethylhexylglycerin

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

We don't have a description for Acetyl Glutamine yet.

Bacillus/Folic Acid Ferment Filtrate Extract is an antioxidant.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of phospholipids.

Thanks to its amphiphilic structure (water-loving head and oil-loving tail), it is a true multitasker:

It plays well with most ingredients and is typically used at 0.1-1%. However, concentrations up to 50% have been reported in moisturizers.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

sh-Oligopeptide-1 is a peptide found naturally in our bodies. Peptides are the building blocks for collagen and elastin in our skin.

In cosmetics, this ingredient is bioengineered to be identical to a human gene that codes for epidermal growth factor (EGF). EGF are signal molecules that simulate cell growth and healing.

Studies find EGF help with:

In South Korea and China, EGF is considered a controversial ingredient. The South Korean Ministry of Food and Drug Safety has cracked down on companies with products including EGF due to false advertisement claims.

According to Dr. Zoe Draelos, growth factors have some drawbacks:

There is also controversy surrounding growth factors. The controversy is due to their mitogenic activity, or their ability to increase the number of cells. It is best to avoid using growth factors if you have psoriasis or are at risk of skin cancer. However, it should be noted EGF are not mutagenic - meaning they will not cause cancer.

This peptide has similar properties to Sh-Oligopeptide-1.

There is also controversy surrounding EGF. The controversy is due to their mitogenic activity, or their ability to increase the number of cells. It is best to avoid using growth factors if you have psoriasis or are at risk of skin cancer. However, it should be noted EGF are not mutagenic - meaning they will not cause cancer.

Sh-Polypeptide-1 is a signal peptide that tells our cells to create more fibroblast cells. Fibroblasts maintain skin structure and plays a role in wound healing.

It is important to note this ingredient is mitogenic and not mutagenic. Meaning it will stimulate cell multiplication, and will not cause cancer.

Sh-Polypeptide-11 is a signal protein that tells our skin to create more fibroblast cells. Fibroblasts maintain skin structure and plays a role in wound healing.

Sh-Polypeptide-9 is a signal peptide that tells our body to create more blood vessels.

It is important to note, this ingredient is mitogenic and not mutagenic. Meaning it will stimulate cell multiplication, and will not cause cancer.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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