Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

innisfree True Vitamin C 23 Ampoule Versus Beauty of Joseon Light On Serum : Centella + Vita C

innisfree True Vitamin C 23 Ampoule Versus Beauty of Joseon Light On Serum : Centella + Vita C This brightening ampoule is formulated around Ascorbic Acid and 3-O-Ethyl Ascorbic Acid to brighten dull-looking skin and fade the look of dark spots. This brighteni

innisfree True Vitamin C 23 Ampoule Versus Beauty of Joseon Light On Serum : Centella + Vita C

This brightening ampoule is formulated around Ascorbic Acid and 3-O-Ethyl Ascorbic Acid to brighten dull-looking skin and fade the look of dark spots.

This brightening serum is formulated around Centella Asiatica Extract and 3-O-Ethyl Ascorbic Acid to brighten dull-looking skin and calm redness.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Ascorbic Acid 23%

Propanediol

Alcohol

Sodium Citrate

1,2-Hexanediol

Panthenol

3-O-Ethyl Ascorbic Acid

Glycerin

Octyldodeceth-16

Butylene Glycol

Glutathione

Sodium Acrylic Acid/Ma Copolymer

Parfum

Disodium EDTA

Ferulic Acid

Tocopherol

Ethylhexylglycerin

Adenosine

Xanthan Gum

Piper Methysticum Leaf/Root/Stem Extract

Hydrogenated Lecithin

Caprylyl Glycol

Phellodendron Amurense Bark Extract

Dextrin

Theobroma Cacao Seed Extract

Citrus Junos Seed Extract

Pvp

Fullerenes

Water, Ascorbic Acid 23%, Propanediol, Alcohol, Sodium Citrate, 1,2-Hexanediol, Panthenol, 3-O-Ethyl Ascorbic Acid, Glycerin, Octyldodeceth-16, Butylene Glycol, Glutathione, Sodium Acrylic Acid/Ma Copolymer, Parfum, Disodium EDTA, Ferulic Acid, Tocopherol, Ethylhexylglycerin, Adenosine, Xanthan Gum, Piper Methysticum Leaf/Root/Stem Extract, Hydrogenated Lecithin, Caprylyl Glycol, Phellodendron Amurense Bark Extract, Dextrin, Theobroma Cacao Seed Extract, Citrus Junos Seed Extract, Pvp, Fullerenes

Centella Asiatica Extract

Betaine

Dicaprylyl Carbonate

Methyl Trimethicone

Cetyl Ethylhexanoate

Laminaria Japonica Extract

Eclipta Prostrata Leaf Extract

Citrus Unshiu Peel Extract

Brassica Oleracea Acephala Leaf Extract

Hydrolyzed Gardenia Florida Extract

Cetearyl Alcohol

Dimethicone/Vinyl Dimethicone Crosspolymer

Silica

Bisabolol

Potassium Cetyl Phosphate

Hydrolyzed Jojoba Esters

Cetearyl Olivate

Sorbitan Olivate

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Ammonium Acryloyldimethyltaurate/Beheneth-25 Methacrylate Crosspolymer

Polyglyceryl-10 Myristate

Fructooligosaccharides

Beta-Glucan

Sorbitan Isostearate

Hydrolyzed Hyaluronic Acid

Maltodextrin

Arginine

Carbomer

Ascorbic Acid Polypeptide

Hydroxyacetophenone

Centella Asiatica Extract, 3-O-Ethyl Ascorbic Acid, Glycerin, Propanediol, Betaine, Dicaprylyl Carbonate, Methyl Trimethicone, Cetyl Ethylhexanoate, Panthenol, Laminaria Japonica Extract, Eclipta Prostrata Leaf Extract, Phellodendron Amurense Bark Extract, Citrus Unshiu Peel Extract, Brassica Oleracea Acephala Leaf Extract, Hydrolyzed Gardenia Florida Extract, Hydrogenated Lecithin, Cetearyl Alcohol, Water, Dimethicone/Vinyl Dimethicone Crosspolymer, Silica, Bisabolol, Potassium Cetyl Phosphate, Hydrolyzed Jojoba Esters, Cetearyl Olivate, Sorbitan Olivate, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Ammonium Acryloyldimethyltaurate/Beheneth-25 Methacrylate Crosspolymer, Xanthan Gum, Polyglyceryl-10 Myristate, Adenosine, Fructooligosaccharides, Beta-Glucan, Butylene Glycol, Sorbitan Isostearate, Hydrolyzed Hyaluronic Acid, Maltodextrin, Arginine, Carbomer, Ascorbic Acid Polypeptide, 1,2-Hexanediol, Hydroxyacetophenone, Ethylhexylglycerin

Reviews

Be the first to review

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

3-O-Ethyl Ascorbic Acid is one of the most popular "stable" vitamin C derivatives in skincare.

Plain ascorbic acid is fantastic but notoriously fragile; it browns, oxidizes, and loses potency fast. So attaching an ethyl group to the third carbon of the molecule gives it some cool perks:

In a formula, it does the 3 classic vitamin C jobs: it acts as an antioxidant, helps brighten skin tone by inhibiting tyrosinase, and supports collagen.

The evidence is reasonably solid for a cosmetic ingredient; Liao and colleagues (2018) showed it's significantly more stable than ascorbic acid while still being effective.

A 2021 study by Zerbinati and colleagues tested a serum with 30% 3-O-ethyl-l-ascorbic acid and 1% lactic acid significantly increased collagen production, reduced UVB-induced DNA damage, and decreased melanin on a reconstructed pigmented skin model.

Typical real world usage sits around 0.5-5% (and 1-2% is common for daily serums).

Amounts up to 30% have been shown to be non-irritating on human skin samples, but two isolated cases reported allergic contact dermatitis so a patch test is sensible if you have reactive skin.

Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.

The way it works is fairly well mapped out:

Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.

The clinical backing is pretty solid too.

A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.

A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.

On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.

This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.

Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Hydrogenated Lecithin is a more stable version of lecithin.

It's made by taking lecithin (a phospholipid commonly found in soybeans and egg yolks) and hydrogenating it. This just means the unsaturated fatty acids are turned into saturated ones so they don't go bad as easily.

This ingredient is an emollient, emulsifier, and penetration enhancer. As an emollient, it helps soften and hydrate skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.

Hydrogenated Lecithin can form tiny spherical structures made of phospholipid bilayers called liposomes. These liposomes are able to capture compounds inside their structure and deliver them through the skin barrier.

Because phospholipids are a natural component of our cell membranes, this ingredient is inherently compatible with skin.

A 2021 study found lecithin-based surfactants were less harsh and more tolerable comared to Sodium Lauryl Sulfate (SLS).

Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.

There are two forms of panthenol: D and L.

D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.

Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):

Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.

This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.

Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.

This ingredient is also referred to as pro-vitamin B5.

This ingredient is also known as Amur cork tree bark. It is a botanical extract with skin conditioning and tonic properties.

Amur tree bark is rich in compounds, such as berberine and palmatine, that are widely studied for antioxidant and anti-inflammatory activity.

In lab research, this ingredient has been shown to reduce inflammation in skin cells exposed to pollution. The results were also linked to PAR-2 signaling, a pathway involved in irritation and barrier stress. This is why you'll see this ingredient in "anti-pollution" skincare.

Preclinical work also suggests anti-inflammatory benefits in atopic-dermatitis models when used topically.

Please note that these studies do not offer strong proof because they do not involve humans. However, this ingredient has low irritation/risk and there's no harm in trying it out.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 031,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
  4. 04It is a:
  5. 05Humectant, drawing moisture into the skin
  6. 06Emollient, helping to soften skin
  7. 07Solvent, dispersing and stabilizing formulas
  8. 08Preservative booster, enhancing the antimicrobial activity of other preservatives
  9. 09Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
  10. 10Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
  11. 11Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
  12. 12Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
  13. 13This ingredient mainly works behind the scenes and helps with:
  14. 14On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
  15. 15One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too st…
  16. 16Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
  17. 17You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
  18. 18Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
  19. 19Topically, glycerin does several things at once:
  20. 20Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Source · skinsort.com
02

Product index

Related product references

Product

Beauty of Joseon Pore Firming Serum

Beauty of Joseon Pore Firming Serum Ingredients in Beauty of Joseon Pore Firming Serum explained: benefits, concerns, and detailed analysis of 27 ingredients including Water, Butylene Glyco…

Source: skinsort.comView reference →

Product

Beauty of Joseon Repair Serum

Beauty of Joseon Repair Serum Beauty of Joseon Repair Serum ingredients explained: Panax Ginseng Root Water, Water, Butylene Glycol, Snail Secretion Filtrate, Dipropylene Glycol, 1,2-Hexane…

Source: incidecoder.comView reference →
03

Comparison edit

Read side by side