Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Isntree Aloe Soothing Gel Fresh Type Versus Beauty of Joseon Red Bean Water Gel

Isntree Aloe Soothing Gel Fresh Type Versus Beauty of Joseon Red Bean Water Gel This calming moisturizer is formulated around Aloe Barbadensis Leaf Extract and Dipotassium Glycyrrhizate to calm redness and hydrate skin. This calming moisturizer is formulated a

Isntree Aloe Soothing Gel Fresh Type Versus Beauty of Joseon Red Bean Water Gel

This calming moisturizer is formulated around Aloe Barbadensis Leaf Extract and Dipotassium Glycyrrhizate to calm redness and hydrate skin.

This calming moisturizer is formulated around Panthenol and Allantoin to calm redness and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

No concerns

Ingredients Side-by-side

Water

Butylene Glycol

Aloe Barbadensis Leaf Extract

Carbomer

Arginine

1,2-Hexanediol

Dipotassium Glycyrrhizate

Allantoin

Propanediol

Panthenol

Glycerin

Ethylhexylglycerin

Betaine

Sodium Hyaluronate

Water, Butylene Glycol, Aloe Barbadensis Leaf Extract, Carbomer, Arginine, 1,2-Hexanediol, Dipotassium Glycyrrhizate, Allantoin, Propanediol, Panthenol, Glycerin, Ethylhexylglycerin, Betaine, Sodium Hyaluronate

Methyl Trimethicone

Phaseolus Angularis Seed Extract

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Tromethamine

Glyceryl Glucoside

C12-14 Alketh-12

Maltodextrin

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Dimethicone/Vinyl Dimethicone Crosspolymer

Dimethicone Crosspolymer

Polyquaternium-51

Xanthan Gum

Disodium EDTA

Glyceryl Acrylate/Acrylic Acid Copolymer

Dioscorea Japonica Root Extract

Glucose

Sodium Citrate

Beta-Glucan

Hydrolyzed Corn Starch

Citric Acid

Sucrose

Magnesium Ascorbyl Phosphate

Caprylyl Glycol

Helianthus Annuus Seed Oil

Tocopherol

Cyanocobalamin

Glycine

Serine

Glutamic Acid

Aspartic Acid

Leucine

Acetyl Hexapeptide-8

Alanine

Lysine

Tyrosine

Phenylalanine

Proline

Threonine

Valine

Isoleucine

Histidine

Cysteine

Methionine

Phosphoric Acid

Ascorbic Acid

Sh-Oligopeptide-1

Sh-Oligopeptide-2

Sh-Polypeptide-1

Water, Butylene Glycol, Glycerin, 1,2-Hexanediol, Methyl Trimethicone, Phaseolus Angularis Seed Extract, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tromethamine, Glyceryl Glucoside, C12-14 Alketh-12, Maltodextrin, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Dimethicone/Vinyl Dimethicone Crosspolymer, Dimethicone Crosspolymer, Ethylhexylglycerin, Betaine, Panthenol, Allantoin, Dipotassium Glycyrrhizate, Polyquaternium-51, Xanthan Gum, Disodium EDTA, Glyceryl Acrylate/Acrylic Acid Copolymer, Dioscorea Japonica Root Extract, Glucose, Sodium Citrate, Beta-Glucan, Hydrolyzed Corn Starch, Citric Acid, Sucrose, Magnesium Ascorbyl Phosphate, Caprylyl Glycol, Helianthus Annuus Seed Oil, Tocopherol, Cyanocobalamin, Glycine, Serine, Glutamic Acid, Aspartic Acid, Leucine, Acetyl Hexapeptide-8, Alanine, Lysine, Arginine, Tyrosine, Phenylalanine, Proline, Threonine, Valine, Isoleucine, Histidine, Cysteine, Methionine, Phosphoric Acid, Ascorbic Acid, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Allantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.

Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.

Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.

It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.

Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.

This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.

Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.

Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.

Arginine is a semi-essential amino acid. This just means our bodies can product a bit on its own, but sometimes needs a little boost from food sources.

It is a part of your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.

Here's an interesting thing about Arginine: your skin converts it into urea through the Krebs-Henseleit urea cycle. Urea is one of the most effective humectants your skin naturally produces.

A clinical study showed applying 2.5% arginine hydrochloride to atopic dermatitis skin showed significant urea levels in the stratum corneum and improved moisture in just four weeks.

Arginine is also a precursor to nitric oxide; nitric oxide improves microcirculation and supports wound healing and collagen synthesis.

One study found that an amino acid complex containing Arginine reduced skin irritation, improved hydration, and accelerated skin repair in clinical / in-vivo studies.

Arginine itself is an amino acid and not a fatty acid, oil, or ester. On its own, it's not a direct food source for Malassezia, or the yeast that causes fungal acne.

Betaine is a humectant. Like hyaluronic acid, it helps attract and retain moisture in the skin. It’s known for being gentle and for helping the skin maintain balanced hydration.

Betaine is mainly used to improve hydration and support calmer skin. It helps skin cells regulate water balance because it functions as an osmolyte.

Some studies suggest betaine may support making skin tone more even.

Fun fact: Betaine naturally exists in the skin and the body. In cosmetic products, it can be either plant-derived (most commonly from sugar beets) or synthetically produced for consistency and stability.

Betaine is also known as trimethylglycine.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Dipotassium Glycyrrhizate comes from licorice root.

Extracts of licorice have demonstrated to have antibacterial, anti‐inflammatory, antiviral, antioxidant properties.

One component, glabridin, has extra potent antioxidant and soothing properties. It has also been found to block pigmentation from UVB rays in guinea pigs.

Licorice Root also contains a flavonoid. Flavonoids are a natural substance from in plants. Flavonoids also have antioxidant properties.

Another component, glycyrrhizin, has been found to have anti-inflammatory and antimicrobial benefits. This may make licorice root extract effective at treating acne. However, more research is needed to support this.

Liquiritin is one of the flavone compounds found in licorice. It has been found to help lighten skin by preventing tyrosinase from reacting with tyrosine. When the two react, protein is converted to melanin. Melanin is the substance in your body that gives your features pigmentation.

Licorice root is native to Southern Europe and Asia. It has been used in traditional Chinese medicine to help with respiratory issues.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.

There are two forms of panthenol: D and L.

D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.

Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):

Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.

This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.

Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.

This ingredient is also referred to as pro-vitamin B5.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Side-by-side

  1. 01Cetyl Ethylhexanoate
  2. 02Caprylic/Capric Triglyceride
  3. 03PEG-20 Glyceryl Triisostearate
  4. 04Synthetic Wax
  5. 05PEG-10 Isostearate
  6. 06Sorbitan Sesquioleate
  7. 07Hippophae Rhamnoides Oil
  8. 08Oryza Sativa Bran Oil
  9. 09Water
  10. 10Oryza Sativa Seed Water
  11. 11Glycerin
  12. 12Propanediol
  13. 131,2-Hexanediol
  14. 14Lactobacillus/Soybean Ferment Extract
  15. 15Butylene Glycol
  16. 16Coix Lacryma-Jobi Ma-Yuen Seed Extract
  17. 17Oryza Sativa Extract
  18. 18Avena Sativa Meal Extract
  19. 19Ethylhexylglycerin
  20. 20Caprylyl Glycol
Source · skinsort.com
02

Product index

Related product references

03

Comparison edit

Read side by side